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Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The forced expression system of MYOD1, a master gene for myogenic differentiation, can efficiently and rapidly reproduce muscle differentiation of human induced pluripotent stem cells (hiPSCs). Despite these advantages of the MYOD1 overexpre
Externí odkaz:
https://doaj.org/article/0288be546cf347c9a9fab5b940690d3e
Autor:
Megumi Yokomizo-Goto, Nana Takenaka-Ninagawa, Chengzhu Zhao, Clémence Kiho Bourgeois Yoshioka, Mayuho Miki, Souta Motoike, Yoshiko Inada, Denise Zujur, William Theoputra, Yonghui Jin, Junya Toguchida, Makoto Ikeya, Hidetoshi Sakurai
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background Ullrich congenital muscular dystrophy (UCMD) is caused by a deficiency in type 6 collagen (COL6) due to mutations in COL6A1, COL6A2, or COL6A3. COL6 deficiency alters the extracellular matrix structure and biomechanical properties
Externí odkaz:
https://doaj.org/article/f340ceaf0581411496358769fb395f06
Autor:
Clémence Kiho Bourgeois Yoshioka, Nana Takenaka-Ninagawa, Megumi Goto, Mayuho Miki, Daiki Watanabe, Masamichi Yamamoto, Tomoki Aoyama, Hidetoshi Sakurai
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Background Duchenne muscular dystrophy (DMD) is an incurable neuromuscular disease leading to progressive skeletal muscle weakness and fatigue. Cell transplantation in murine models has shown promise in supplementing the lack of the dystroph
Externí odkaz:
https://doaj.org/article/c8652efa539f471d8520c99fa9124f5a
Publikováno v:
Journal of Arrhythmia, Vol 40, Iss 4, Pp 802-814 (2024)
Abstract Background Previous studies have shown inconsistent results in clinical effectiveness between cryoballoon ablation (CBA) and radiofrequency ablation (RFA), and cost assessment between the procedures is important. The aim of this study was to
Externí odkaz:
https://doaj.org/article/b6a0157fd83a4cf7a0f550433ca0815c
Autor:
Keiji Komatsu, Takuya Kudo, Zhenyu Guo, Liang Shaoji, Atsushi Nakamura, Osamu Ito, Hidetoshi Saitoh
Publikováno v:
Results in Surfaces and Interfaces, Vol 17, Iss , Pp 100304- (2024)
Direct metal Ni and Cu coatings were formed on various substrates using a metal-ethylenediaminetetraacetic acid (EDTA) complex solution followed by treatment with a high-heat hydrogen/oxygen (H2–O2) coupled flame. Mortar, alumina, and SUS304 were u
Externí odkaz:
https://doaj.org/article/e3a07be2876f4a9781fa16a005f64ead
Autor:
Hidetoshi Shimizu, Michael A. Tortorici, Yoshiyasu Ohta, Kei Ogawa, Sheikh Mohammed Ashfaq Rahman, Aya Fujii, Yuki Hiraga, Mizue Kawai, Kanami Sugimoto‐Kawabata, Mattheus (Thijs) vanIersel, Jan Jaap vanLier, Stephen Djedjos, B. T. Slingsby, David M. Rodman
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 8, Pp n/a-n/a (2024)
Abstract Dysregulation of the mineralocorticoid hormone aldosterone is an increasingly prevalent cause of hypertension. Aldosterone synthase (CYP11B2) shares 93% homology to 11β‐hydroxylase (CYP11B1), which produces cortisol. Lorundrostat, a highl
Externí odkaz:
https://doaj.org/article/c92800d2ef6c453baa9149dda089faef
Autor:
Masaki Shoji, Takuto Ohashi, Saki Nagase, Haato Yuri, Kenta Ichihashi, Teruhisa Takagishi, Yuji Nagata, Yuki Nomura, Ayako Fukunaka, Sae Kenjou, Hatsuna Miyake, Takafumi Hara, Emi Yoshigai, Yoshio Fujitani, Hidetoshi Sakurai, Heloísa G. dos Santos, Toshiyuki Fukada, Takashi Kuzuhara
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Ehlers–Danlos syndrome spondylodysplastic type 3 (EDSSPD3, OMIM 612350) is an inherited recessive connective tissue disorder that is caused by loss of function of SLC39A13/ZIP13, a zinc transporter belonging to the Slc39a/ZIP family. We pr
Externí odkaz:
https://doaj.org/article/66db52930fec4ff4bbbebbc1c0f96d83
Autor:
Hidetoshi Shiroishi
Publikováno v:
Maketingu Janaru, Vol 43, Iss 4, Pp 96-105 (2024)
Tatami is a traditional Japanese flooring. The industry has declined due to the westernization of housing. Generally, tatami stores operate by establishing their business with deep roots in the local community. Their markets are geographically restri
Externí odkaz:
https://doaj.org/article/b9b32772450943e2a0efe8ef1e68d600
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease caused by a gain-of-function mutation in ACVR1, which is a bone morphogenetic protein (BMP) type I receptor. Moreover, it causes progressive heterotopic ossific
Externí odkaz:
https://doaj.org/article/6a24b948d17942799a13d0d29082b2e3