Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Hidetomo Yokoo"'
Autor:
Miki Suzuki, Yuki Mochida, Mao Hori, Akimasa Hayashi, Kazuko Toh, Theofilus A. Tockary, Xueying Liu, Victor Marx, Hidetomo Yokoo, Kanjiro Miyata, Makoto Oba, Satoshi Uchida
Publikováno v:
Small Science, Vol 4, Iss 4, Pp n/a-n/a (2024)
Organ‐selective targeting of mRNA polyplexes has been rarely explored despite the substantial potential of polymer‐based systems in mRNA delivery. In this study, spleen‐selective delivery of polyplexes is achieved by employing mRNA engineering
Externí odkaz:
https://doaj.org/article/fe7bde1132c74192b0fb44db21d9b503
Publikováno v:
ACS Omega, Vol 8, Iss 46, Pp 44106-44111 (2023)
Externí odkaz:
https://doaj.org/article/fd47183cf162473e9dd4c96b3128edb7
Autor:
Hanqiao Xu, Nobumichi Ohoka, Hidetomo Yokoo, Kanako Nemoto, Takashi Ohtsuki, Hiroshi Matsufuji, Mikihiko Naito, Takao Inoue, Genichiro Tsuji, Yosuke Demizu
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Liver X receptors (LXRs) belong to the nuclear hormone receptor superfamily and function as ligand-dependent transcription factors that regulate cholesterol homeostasis, lipid homeostasis, and immune responses. LXR antagonists are promising treatment
Externí odkaz:
https://doaj.org/article/ae88e5afc088454faabd03455637e750
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 78 (2021)
Messenger RNAs (mRNAs) were previously shown to have great potential for preventive vaccination against infectious diseases and therapeutic applications in the treatment of cancers and genetic diseases. Delivery systems for mRNAs, including lipid- an
Externí odkaz:
https://doaj.org/article/c52f2e4546634c80a373e7da13b7c122
Autor:
Motoharu Hirano, Chihiro Saito, Hidetomo Yokoo, Chihiro Goto, Ryuji Kawano, Takashi Misawa, Yosuke Demizu
Publikováno v:
Molecules, Vol 26, Iss 2, p 444 (2021)
Magainin 2 (Mag2), which was isolated from the skin of the African clawed frog, is a representative antimicrobial peptide (AMP) that exerts antimicrobial activity via microbial membrane disruption. It has been reported that the helicity and amphipath
Externí odkaz:
https://doaj.org/article/54313c8ebd78468ba8a0071048beccf9
Publikováno v:
Expert Opinion on Drug Discovery. 18:357-361
Autor:
Makoto Oba, Mika Shibuya, Yuto Yamaberi, Hidetomo Yokoo, Satoshi Uchida, Atsushi Ueda, Masakazu Tanaka
Publikováno v:
Chemical and Pharmaceutical Bulletin. 71(3):250-256
Amphipathic peptides composed of cationic amino acids and hydrophobic amino acids have cell-penetrating ability and are often used as a delivery tool for membrane-impermeable compounds. Small interfering RNA (siRNAs) are one of the delivery targets f
Autor:
Hidetomo Yokoo, Seiji Tanaka, Eiichi Yamamoto, Genichiro Tsuji, Yosuke Demizu, Nahoko Uchiyama
Publikováno v:
Chemical and Pharmaceutical Bulletin. 71:58-63
Autor:
Hidetomo Yokoo
Publikováno v:
Cell‐Penetrating Peptides. :219-236
Publikováno v:
Journal of Synthetic Organic Chemistry, Japan. 80:922-929