Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Hidetomo Iwano"'
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Phage therapy has re-emerged in modern medicine as a robust antimicrobial strategy in response to the increasing prevalence of antimicrobial-resistant bacteria. However, bacterial resistance to phages can also arise via a variety of molecular mechani
Externí odkaz:
https://doaj.org/article/fe8eb90a2be7445d8e9eff04374008ee
Autor:
Katsuhito Sugai, Miki Kawada-Matsuo, Mi Nguyen-Tra Le, Yo Sugawara, Junzo Hisatsune, Jumpei Fujiki, Hidetomo Iwano, Kotaro Tanimoto, Motoyuki Sugai, Hitoshi Komatsuzawa
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108465- (2023)
Summary: Bacteriophages are expected to be therapeutic agents against infectious diseases. Streptococcus mutans are involved in dental plaque formation related to dental caries and periodontitis. In S. mutans, lytic bacteriophages have been isolated
Externí odkaz:
https://doaj.org/article/814901e446ed49bd8f90cb41b5586eb7
Autor:
Jumpei Fujiki, Tomohiro Nakamura, Keisuke Nakamura, Keita Nishida, Yurika Amano, Yusaku Watanabe, Satoshi Gondaira, Masaru Usui, Masaru Shimizu, Kazuhiko Miyanaga, Shinya Watanabe, Tomohito Iwasaki, Kotaro Kiga, Tomoko Hanawa, Hidetoshi Higuchi, Teiji Sawa, Yasunori Tanji, Yutaka Tamura, Longzhu Cui, Hidetomo Iwano
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Staphylococcus virus ΦSA012 has a wide host range and efficient lytic activity. Here, we assessed the biological stability of ΦSA012 against temperature, freeze-thawing, and pH to clinically apply the phage. In addition, inoculation of ΦS
Externí odkaz:
https://doaj.org/article/6f8f05107af54089ad955e9819745265
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15628 (2023)
In recent decades, phage therapy has been overshadowed by the widespread use of antibiotics in Western countries. However, it has been revitalized as a powerful approach due to the increasing prevalence of antimicrobial-resistant bacteria. Although b
Externí odkaz:
https://doaj.org/article/363d0bf96c4d410cb3ac9e2bf954adf5
Autor:
Satoshi Gondaira, Koji Nishi, Jumpei Fujiki, Hidetomo Iwano, Reina Watanabe, Ayako Eguchi, Yuki Hirano, Hidetoshi Higuchi, Hajime Nagahata
Publikováno v:
Veterinary Research, Vol 52, Iss 1, Pp 1-11 (2021)
Abstract Mycoplasma bovis (M. bovis) is a significant worldwide pathogen of cattle. Neutrophils have an important role in the innate immune response during infection with M. bovis. However, even though neutrophils accumulate in M. bovis infection, th
Externí odkaz:
https://doaj.org/article/8ddcb3337aa141579beedb5632bd7079
Autor:
Tomohiro Nakamura, Junya Kitana, Jumpei Fujiki, Masayuki Takase, Keita Iyori, Kenta Simoike, Hidetomo Iwano
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
The spread of antibiotic-resistant bacteria (ARB) in human and veterinary medicine is of global concern. Notably, the emergence of methicillin-resistant Staphylococcus pseudintermedius has become a serious problem. In this context, bacteriophages and
Externí odkaz:
https://doaj.org/article/da7c38b9085841d484f7156f85932d8e
Autor:
Mutsumi Furukawa, Hiroshi Yoneyama, Eiji Hata, Hidetomo Iwano, Hidetoshi Higuchi, Tasuke Ando, Mika Sato, Tomohito Hayashi, Yoshio Kiku, Yuya Nagasawa, Kanae Niimi, Katsuki Usami, Kumiko Ito, Kouichi Watanabe, Tomonori Nochi, Hisashi Aso
Publikováno v:
Veterinary Research, Vol 49, Iss 1, Pp 1-12 (2018)
Abstract Staphylococcus aureus is a major pathogen that causes subclinical mastitis associated with huge economic losses to the dairy industry. A few vaccines for bovine mastitis are available, and they are expected to induce the production of S. aur
Externí odkaz:
https://doaj.org/article/d4cd8a5111834e59af2c8891e384e785
Autor:
Jumpei Fujiki, Shin-ichi Yoshida, Tomohiro Nakamura, Keisuke Nakamura, Yurika Amano, Keita Nishida, Keitaro Nishi, Michihito Sasaki, Tomohito Iwasaki, Hirofumi Sawa, Hitoshi Komatsuzawa, Hiroshi Hijioka, Hidetomo Iwano
Publikováno v:
Viruses, Vol 13, Iss 10, p 1964 (2021)
Bacteriophages are viruses that specifically infect bacteria and are classified as either virulent phages or temperate phages. Despite virulent phages being promising antimicrobial agents due to their bactericidal effects, the implementation of phage
Externí odkaz:
https://doaj.org/article/d02a3dcc933840e583179b7b47dc863f
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Extra-adrenal steroid hormone production has been reported in several tissues, the biological role of which is interesting in terms of hormonal regulation of metabolism, growth, and behavior. In this report, we describe for the first time steroidogen
Externí odkaz:
https://doaj.org/article/352317fc148c40a7b481dbf20b2f7e5d
Autor:
Jumpei Fujiki, Tomohiro Nakamura, Takaaki Furusawa, Hazuki Ohno, Hiromichi Takahashi, Junya Kitana, Masaru Usui, Hidetoshi Higuchi, Yasunori Tanji, Yutaka Tamura, Hidetomo Iwano
Publikováno v:
Pharmaceuticals, Vol 11, Iss 1, p 25 (2018)
Antibiotic-resistant bacteria (ARB) have spread widely and rapidly, with their increased occurrence corresponding with the increased use of antibiotics. Infections caused by Staphylococcus aureus have a considerable negative impact on human and lives
Externí odkaz:
https://doaj.org/article/c6126b2a32c54ee9a50bfba857ee69c8