Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Hidetomo, Yokoo"'
Autor:
Miki Suzuki, Yuki Mochida, Mao Hori, Akimasa Hayashi, Kazuko Toh, Theofilus A. Tockary, Xueying Liu, Victor Marx, Hidetomo Yokoo, Kanjiro Miyata, Makoto Oba, Satoshi Uchida
Publikováno v:
Small Science, Vol 4, Iss 4, Pp n/a-n/a (2024)
Organ‐selective targeting of mRNA polyplexes has been rarely explored despite the substantial potential of polymer‐based systems in mRNA delivery. In this study, spleen‐selective delivery of polyplexes is achieved by employing mRNA engineering
Externí odkaz:
https://doaj.org/article/fe7bde1132c74192b0fb44db21d9b503
Publikováno v:
ACS Omega, Vol 8, Iss 46, Pp 44106-44111 (2023)
Externí odkaz:
https://doaj.org/article/fd47183cf162473e9dd4c96b3128edb7
Autor:
Keisuke Tsuchiya, Kanako Horikoshi, Minami Fujita, Motoharu Hirano, Maho Miyamoto, Hidetomo Yokoo, Yosuke Demizu
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11768 (2023)
Cell-penetrating peptides (CPPs) are widely used for the intracellular delivery of a variety of cargo molecules, including small molecules, peptides, nucleic acids, and proteins. Many cationic and amphiphilic CPPs have been developed; however, there
Externí odkaz:
https://doaj.org/article/93b752e4577046818092b656962bd457
Autor:
Hanqiao Xu, Dr. Takashi Kurohara, Reina Takano, Dr. Hidetomo Yokoo, Dr. Norihito Shibata, Dr. Nobumichi Ohoka, Dr. Takao Inoue, Prof. Mikihiko Naito, Dr. Yosuke Demizu
Publikováno v:
ChemistryOpen, Vol 11, Iss 7, Pp n/a-n/a (2022)
Abstract Optimizing linker design is important for ensuring efficient degradation activity of proteolysis‐targeting chimeras (PROTACs). Therefore, developing a straightforward synthetic approach that combines the protein‐of‐interest ligand (POI
Externí odkaz:
https://doaj.org/article/2f0a8ecceb984a30b13e6945b3ae6014
Publikováno v:
Expert Opinion on Drug Discovery. 18:357-361
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7068370849d3b8f0db0e7c4248049e8e
https://doi.org/10.1080/17460441.2023.2187047
https://doi.org/10.1080/17460441.2023.2187047
Autor:
Makoto Oba, Mika Shibuya, Yuto Yamaberi, Hidetomo Yokoo, Satoshi Uchida, Atsushi Ueda, Masakazu Tanaka
Publikováno v:
Chemical and Pharmaceutical Bulletin. 71(3):250-256
Amphipathic peptides composed of cationic amino acids and hydrophobic amino acids have cell-penetrating ability and are often used as a delivery tool for membrane-impermeable compounds. Small interfering RNA (siRNAs) are one of the delivery targets f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7437cde815ffee19c8da6a2c91d77a8
https://nagasaki-u.repo.nii.ac.jp/records/28007
https://nagasaki-u.repo.nii.ac.jp/records/28007
Autor:
Hanqiao Xu, Nobumichi Ohoka, Hidetomo Yokoo, Kanako Nemoto, Takashi Ohtsuki, Hiroshi Matsufuji, Mikihiko Naito, Takao Inoue, Genichiro Tsuji, Yosuke Demizu
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Liver X receptors (LXRs) belong to the nuclear hormone receptor superfamily and function as ligand-dependent transcription factors that regulate cholesterol homeostasis, lipid homeostasis, and immune responses. LXR antagonists are promising treatment
Externí odkaz:
https://doaj.org/article/ae88e5afc088454faabd03455637e750
Autor:
Hidetomo Yokoo, Seiji Tanaka, Eiichi Yamamoto, Genichiro Tsuji, Yosuke Demizu, Nahoko Uchiyama
Publikováno v:
Chemical and Pharmaceutical Bulletin. 71:58-63
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::742fa56482abc47264ca253f5b525ffc
https://doi.org/10.1248/cpb.c22-00628
https://doi.org/10.1248/cpb.c22-00628
Autor:
Hidetomo Yokoo
Publikováno v:
Cell‐Penetrating Peptides. :219-236
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68030c3775bd7f4fa6d2062cb626add8
https://doi.org/10.1002/9783527835997.ch13
https://doi.org/10.1002/9783527835997.ch13
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 78 (2021)
Messenger RNAs (mRNAs) were previously shown to have great potential for preventive vaccination against infectious diseases and therapeutic applications in the treatment of cancers and genetic diseases. Delivery systems for mRNAs, including lipid- an
Externí odkaz:
https://doaj.org/article/c52f2e4546634c80a373e7da13b7c122