Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hideto Ohno"'
Autor:
Hirokazu Matsumoto, Tohru Yamaji, Masahiko Fujino, Hihoo Johshita, Hideto Ohno, Fumimaro Takaku, Miyuki Ishibashi, Nobuhiro Suzuki
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 71:1611-1615
To clarify whether endothelin may be present in human cerebrospinal fluid (CSF) and, if it exists, to compare its molecular forms with those of endothelin in human plasma, we analyzed pooled human CSF and plasma by high performance liquid chromatogra
Autor:
Mitsuhide Naruse, Michiaki Hiroe, Kiyoko Naruse, Makoto Nagata, Hideto Ohno, Akimasa Hashimoto, Hitoshi Koyanagi, Morie Sekiguchi, Hiroshi Demura, Koushichiro Hirosawa, Tadashi Inagami, Kazuo Shizume
Publikováno v:
American Journal of Hypertension. 3:105-110
The levels and molecular form of atrial natriuretic peptide-like immunoreactivity (ANP-LI) in human atrial tissue were investigated. The levels of right atrial ANP-LI were significantly higher in mitral disease than in other cardiac or noncardiac dis
Autor:
Katsuya, Urakami, Noburo, Ito, Hiroyuki, Arai, Kouichi, Ishiguro, Hideto, Ohno, Kenji, Nakashima
Publikováno v:
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. 105(4)
We examined total 570 cerebrospinal fluid (CSF) samples from a variety of diseases, including Alzheimer's disease (AD; n = 236), non-AD-demented and nondemented diseases (n = 239), and normal controls (n = 95) to quantitate levels of tau protein phos
Autor:
Nobuo Itoh, Koichi Ishiguro, Yu Ichi Morikawa, Hideto Ohno, Toshifumi Matsui, Hidetada Sasaki, Hideki Kohno, Hiroyuki Arai, Etsuo Horikawa, Kazutomo Imahori, Nobuyuki Okamura, Michiko Moriyama
Publikováno v:
Experimental neurology. 166(1)
Cerebrospinal fluid (CSF) tau protein phosphorylated at both Thr231 and Ser235 sites (CSF/phospho-tau(231-235)) and total tau (CSF/total-tau) were quantified by sandwich ELISA in 20 patients with mild cognitive impairment (MCI) who eventually develop
Autor:
Jung-Mi Park, Hideki Kohno, Hideto Ohno, Katsuya Urakami, Haruyasu Yamaguchi, Hiroyuki Arai, Kazutomo Imahori, Kazuki Sato, Koichi Ishiguro
Publikováno v:
Neuroscience letters. 270(2)
Microtubule-associated protein tau in cerebrospinal fluid (CSF) has been proposed as a diagnostic marker for Alzheimer's disease (AD), but there is overlap between AD patients and non-AD controls. To improve the diagnostic accuracy, we measured phosp
Publikováno v:
Journal of immunoassay. 17(1)
An Immunoradiometric assay for thymosin alpha 1(1-28) was developed using a monoclonal and a polyclonal antiserum which were raised against synthetic thymosin alpha 1(1-28) and thymosin alpha 1(16-28), respectively. A monoclonal antibody, specific fo
Autor:
Daisuke Inoue, Kyoji Ikeda, Etsuro Ogata, Toshio Matsumoto, Yasuyuki Ohnishi, Yumiko Nagai, Hideto Ohno, Yoshito Ueyama, Hideyuki Yamato
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 10(1)
The present study was undertaken to clarify in vivo the temporal profile of parathyroid hormone-related peptide (PTHRP) gene expression as well as bone histomorphometric features as a function of tumor growth, using an athymic rat model associated wi
Autor:
Tamotsu Shibasaki, Hideto Ohno, Nicholas Ling, Mari Hotta, Robert Benoit, Naoko Yamauchi, Hiroshi Demura
Publikováno v:
Life sciences. 48(15)
The effects of chronic central administration of corticotropin-releasing factor (CRF) on food intake, body weight, and hypothalamic-pituitary-adrenocortical hormones were investigated in rats. The infusion of ovine CRF at doses of 0.3 and 1.0 microgr
Autor:
Yoshiro Nakamura, Masatoshi Kusuhara, Shingo Hori, Keiichi Fukuda, Ken Yamaguchi, Shunnosuke Handa, Hideto Ohno, Soushin Inoue, Shingo Kyotani, Toru Satoh
Publikováno v:
Cardiovascular research. 24(12)
Study objective – The aim was to determine the site of coronary vasoconstriction induced by endothelin, by investigating the response in terms of retrograde pressure and reactive hyperaemia. Experimental material – Twelve anaesthetised mongrel do
Autor:
Stefan J. Teipel, John DeBernardis, Alexander Goernitz, Cheryl McCulloch, Koichi Ishiguro, Niels Andreasen, Eugeen Vanmechelen, Hugo Vanderstichele, Daniel J. Kerkman, Raymond Zinkowski, Hideto Ohno, Harald Hampel, Katharina Buerger, Magnus Sjoegren, Hans-Jürgen Möller, Peter Davies, Kaj Blennow
Publikováno v:
Archives of General Psychiatry. 61:95
Abnormal hyperphosphorylation of the microtubule-associated protein tau and its incorporation into neurofibrillary tangles are major hallmarks of the pathogenesis of Alzheimer disease (AD). Different tau phosphoepitopes can be sensitively detected in