Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Hideto Morimoto"'
Autor:
Sachiho Kida, Yuri Koshimura, Eiji Yoden, Aya Yoshioka, Hideto Morimoto, Atsushi Imakiire, Noboru Tanaka, Satowa Tanaka, Ayaka Mori, Jun Ito, Asuka Inoue, Ryuji Yamamoto, Kohtaro Minami, Tohru Hirato, Kenichi Takahashi, Hiroyuki Sonoda
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 439-449 (2023)
Mucopolysaccharidosis I (MPS I), a lysosomal storage disease caused by dysfunction of α-L-iduronidase (IDUA), is characterized by the deposition of dermatan sulfate (DS) and heparan sulfate (HS) throughout the body, which causes several somatic and
Externí odkaz:
https://doaj.org/article/c4fd5548bc6941a2962304a79b9b0f89
Autor:
Hideto Morimoto, Hiroki Morioka, Atsushi Imakiire, Ryuji Yamamoto, Tohru Hirato, Hiroyuki Sonoda, Kohtaro Minami
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 534-544 (2022)
Deposition of heparan sulfate (HS) in the brain of patients with mucopolysaccharidosis II (MPS II) is believed to be the leading cause of neurodegeneration, resulting in several neurological signs and symptoms, including neurocognitive impairment. We
Externí odkaz:
https://doaj.org/article/4eedbba9a32d4c1babcaa2d7cd77f6c7
Autor:
Kohtaro Minami, Hideto Morimoto, Hiroki Morioka, Atsushi Imakiire, Masafumi Kinoshita, Ryuji Yamamoto, Tohru Hirato, Hiroyuki Sonoda
Publikováno v:
International journal of molecular sciences. 23(19)
Heparan sulfate (HS) is an essential glycosaminoglycan (GAG) as a component of proteoglycans, which are present on the cell surface and in the extracellular matrix. HS-containing proteoglycans not only function as structural constituents of the basal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff4e0404f5bb3e4708636d38c223915
https://pubmed.ncbi.nlm.nih.gov/36233030
https://pubmed.ncbi.nlm.nih.gov/36233030
Autor:
Asuka Inoue, Jun Ito, Sachiho Kida, Atsushi Imakiire, Kazuki Miyauchi, Yuri Koshimura, Shinji Kakimoto, Hideto Morimoto, Ryuji Yamamoto, Kohtaro Minami, Tohru Hirato, Hiroyuki Sonoda
Publikováno v:
Molecular Genetics and Metabolism. 138:107163
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e226238ef6f404379a1cece897a8a399
https://doi.org/10.1016/j.ymgme.2022.107163
https://doi.org/10.1016/j.ymgme.2022.107163
Autor:
Atsushi Imakiire, Yasunori Sugano, Tadao Shibasaki, Eiji Yoden, Kazuki Miyauchi, Ryuji Yamamoto, Hideto Morimoto, Kohtaro Minami, Tohru Hirato, Hiroyuki Sonoda, Kenichi Takahashi
Publikováno v:
Molecular Genetics and Metabolism. 138:107162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dc7856692f3a871412c02ae5dc731de
https://doi.org/10.1016/j.ymgme.2022.107162
https://doi.org/10.1016/j.ymgme.2022.107162
Autor:
Eiji Yoden, Takashi Onouchi, Saki Fujiyama, Sachiho Kida, Hidehiko Hashimoto, Wataru Machida, Noboru Tanaka, Hideto Morimoto, Tadao Shibasaki, Kohtaro Minami, Tohru Hirato, Hiroyuki Sonoda, Kenichi Takahashi
Publikováno v:
Molecular Genetics and Metabolism. 138:107364
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1188c3d2d80e5f41b234379c3ec59eb2
https://doi.org/10.1016/j.ymgme.2022.107364
https://doi.org/10.1016/j.ymgme.2022.107364
Autor:
Hideto Morimoto, Hiroki Morioka, Atsushi Imakiire, Ryuji Yamamoto, Tohru Hirato, Hiroyuki Sonoda, Kohtaro Minami
Publikováno v:
Molecular Genetics and Metabolism. 138:107230
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6df9646350b8c6c9e430547cd31d9f80
https://doi.org/10.1016/j.ymgme.2022.107230
https://doi.org/10.1016/j.ymgme.2022.107230
Autor:
Norio Sakai, Yuji Sato, Hiroyuki Sonoda, Mathias Schmidt, Kazunori Tanizawa, Mariko Yamaoka, Sairei So, Ana Maria Martins, Hideto Morimoto, Toshiaki Ikeda, Yoshikatsu Eto, Tatsuyoshi Yamamoto, Torayuki Okuyama, Kohtaro Minami, Roberto Giugliani, Kimitoshi Nakamura
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10938, p 10938 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 20
International Journal of Molecular Sciences
Volume 22
Issue 20
Enzyme replacement therapy (ERT) improves somatic manifestations in mucopolysaccharidoses (MPS). However, because intravenously administered enzymes cannot cross the blood–brain barrier (BBB), ERT is ineffective against the progressive neurodegener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d3ab997444c8eaae68c9f600ec5a70
https://www.mdpi.com/1422-0067/22/20/10938
https://www.mdpi.com/1422-0067/22/20/10938
Autor:
Masafumi Kinoshita, Kohtaro Minami, Kenichi Takahashi, Tohru Hirato, Haruna Takagi, Sachiho Kida, Ryuji Yamamoto, Yuri Koshimura, Eiji Yoden, Hiroyuki Sonoda, Hideto Morimoto, Noboru Tanaka
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 29(5)
Mucopolysaccharidosis II (MPS II), a lysosomal storage disease caused by mutations in iduronate-2-sulfatase (IDS), is characterized by a wide variety of somatic and neurologic symptoms. The currently approved intravenous enzyme replacement therapy wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c859c7c0c81ce55d1348dfde95254d
https://pubmed.ncbi.nlm.nih.gov/33508431
https://pubmed.ncbi.nlm.nih.gov/33508431
Autor:
Asuka Inoue, Satowa Tanaka, Sachiho Kida, Yuri Koshimura, Shinji Kakimoto, Atsushi Imakiire, Jun Ito, Kazuki Miyauchi, Hideto Morimoto, Kohtaro Minami, Tohru Hirato, Hiroyuki Sonoda
Publikováno v:
Molecular Genetics and Metabolism. 135:S60
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dc77fe302402a4cc72535c97276915d
https://doi.org/10.1016/j.ymgme.2021.11.150
https://doi.org/10.1016/j.ymgme.2021.11.150