Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Hideto Kojima"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Bone marrow-derived cells (BMDCs) are heterogeneous populations in which not only pluripotent stem cells, namely, hematopoietic stem cells (HSCs), mesenchymal stem cells (MSC) but also endothelial progenitor cells (EPC) are involved. BMDCs contribute
Externí odkaz:
https://doaj.org/article/243b69cded544e799cad6890b1d6735f
Autor:
Hitomi Fujikawa, Hideto Kojima, Tomoya Terashima, Miwako Katagi, Takafumi Yayama, Kosuke Kumagai, Kanji Mori, Hideki Saito, Shinji Imai
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background Diabetes mellitus (DM) causes bone dysfunction due to poor bone quality, leading to severe deterioration in patient of quality of life. The mechanisms of bone metabolism in DM remain unclear, although chemical and/or mechanical fa
Externí odkaz:
https://doaj.org/article/0e3531dc925b44ee93b3f43e4075843f
Autor:
Hideto Kojima, Miwako Katagi, Junko Okano, Yuki Nakae, Natsuko Ohashi, Kazunori Fujino, Itsuko Miyazawa, Takahiko Nakagawa
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Despite the growing epidemic worldwide, diabetes is an incurable disease. We have been focusing on why diabetes manifests refractoriness to any therapy. We recently found that abnormal bone marrow-derived cells (BMDCs), namely, Vcam-1+ST-HSC
Externí odkaz:
https://doaj.org/article/23671901db2d4547b23779f640d86201
Autor:
Yuuki Shirai, Junko Okano, Takahiko Nakagawa, Miwako Katagi, Yuki Nakae, Atsuhiro Arakawa, Shinya Koshinuma, Gaku Yamamoto, Hideto Kojima
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Deep skin wounds with periosteal defects, frequently caused by traffic accidents or radical dissection, are refractory. Transplant surgery is frequently performed, but patients are subjected to stress for long operation periods, the sacrific
Externí odkaz:
https://doaj.org/article/38647d5ca48a4c0998eb0a0c92f32d44
Autor:
Natsuko Ohashi, Tomoya Terashima, Miwako Katagi, Yuki Nakae, Junko Okano, Yoshihisa Suzuki, Hideto Kojima
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Amyotrophic lateral sclerosis (ALS) is an intractable neurodegenerative disease. CD68-positive bone marrow (BM)-derived cells (BMDCs) accumulate in the pathological lesion in the SOD1(G93A) ALS mouse model after BM transplantation (BMT). The
Externí odkaz:
https://doaj.org/article/54be9e626a714971ae9b84bc8055e8a3
Autor:
Miwako Katagi, Tomoya Terashima, Natsuko Ohashi, Yuki Nakae, Akane Yamada, Takahiko Nakagawa, Itsuko Miyazawa, Hiroshi Maegawa, Junko Okano, Yoshihisa Suzuki, Kazunori Fujino, Yutaka Eguchi, Hideto Kojima
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Katagi et al. show that abnormal bone marrow-derived cells originated from hematopoietic stem cells (CD106-positive short-term HSCs) aberrantly fuse with neurons to develop diabetic neuropathy. This study suggests that the pathological abnormality is
Externí odkaz:
https://doaj.org/article/e89bf4e21fc54a66a503dcaba1d6baae
Autor:
Rika Zen, Tomoya Terashima, Shunichiro Tsuji, Miwako Katagi, Natsuko Ohashi, Yuri Nobuta, Asuka Higuchi, Hirohiko Kanai, Takashi Murakami, Hideto Kojima
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundThe pathophysiology of neonatal hypoxic-ischemic encephalopathy (HIE) has been studied in several rodent models to develop novel treatments. Although it is well known that high ambient temperature results in severe HIE, the effect of subtle
Externí odkaz:
https://doaj.org/article/8249c00aa0bc4caba330e5d222535aff
Autor:
Junko Okano, Yuki Nakae, Takahiko Nakagawa, Miwako Katagi, Tomoya Terashima, Daisuke Nagakubo, Takashi Nakayama, Osamu Yoshie, Yoshihisa Suzuki, Hideto Kojima
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Exposure to moderate doses of ionizing radiation (IR), which is sufficient for causing skin injury, can occur during radiation therapy as well as in radiation accidents. Radiation-induced skin injury occasionally recovers, although its under
Externí odkaz:
https://doaj.org/article/6af682acd4a34395939e1f2e7783ce9b
Autor:
Hiroshi Takamura, Tomoya Terashima, Kanji Mori, Miwako Katagi, Junko Okano, Yoshihisa Suzuki, Shinji Imai, Hideto Kojima
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 657-665 (2020)
Treating neuropathic pain is a critical clinical issue. Although numerous therapies have been proposed, effective treatments have not been established. Therefore, safe and feasible treatment methods are urgently needed. In this study, we investigated
Externí odkaz:
https://doaj.org/article/12769ee98652454db6e42fd2cc6dd20c
Autor:
Takahiko Nakagawa, Laura G. Sanchez-Lozada, Ana Andres-Hernando, Hideto Kojima, Masato Kasahara, Bernardo Rodriguez-Iturbe, Petter Bjornstad, Miguel A. Lanaspa, Richard J. Johnson
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Chronic low-grade inflammation underlies the pathogenesis of non-communicable diseases, including chronic kidney diseases (CKD). Inflammation is a biologically active process accompanied with biochemical changes involving energy, amino acid, lipid an
Externí odkaz:
https://doaj.org/article/0bde6256e56a4cfc94c13c23205dae64