Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Hidetake Kurihara"'
Autor:
Shunsuke Tanigawa, Mazharul Islam, Sazia Sharmin, Hidekazu Naganuma, Yasuhiro Yoshimura, Fahim Haque, Takumi Era, Hitoshi Nakazato, Koichi Nakanishi, Tetsushi Sakuma, Takashi Yamamoto, Hidetake Kurihara, Atsuhiro Taguchi, Ryuichi Nishinakamura
Publikováno v:
Stem Cell Reports, Vol 11, Iss 3, Pp 727-740 (2018)
Summary: Mutations in the NPHS1 gene, which encodes NEPHRIN, cause congenital nephrotic syndrome, resulting from impaired slit diaphragm (SD) formation in glomerular podocytes. However, methods for SD reconstitution have been unavailable, thereby lim
Externí odkaz:
https://doaj.org/article/61ad8e59ff20448cb85f40d1f4662589
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150886 (2016)
Macrophage-mediated inflammation has been implicated in various kidney diseases. We previously reported that Rac1, a Rho family small GTP-binding protein, was overactivated in several chronic kidney disease models, and that Rac1 inhibitors ameliorate
Externí odkaz:
https://doaj.org/article/120e2a0e9d154280a156298f7dc1d0b1
Autor:
Koichiro Ichimura, Ekaterina Bubenshchikova, Rebecca Powell, Yayoi Fukuyo, Tomomi Nakamura, Uyen Tran, Shoji Oda, Minoru Tanaka, Oliver Wessely, Hidetake Kurihara, Tatsuo Sakai, Tomoko Obara
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45286 (2012)
The glomerulus of the vertebrate kidney links the vasculature to the excretory system and produces the primary urine. It is a component of every single nephron in the complex mammalian metanephros and also in the primitive pronephros of fish and amph
Externí odkaz:
https://doaj.org/article/07db798a5f4f47129ef0682e4fc5f781
Autor:
Tomonori Hirose, Daisuke Satoh, Hidetake Kurihara, Chiho Kusaka, Hiroko Hirose, Kazunori Akimoto, Taiji Matsusaka, Iekuni Ichikawa, Tetsuo Noda, Shigeo Ohno
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4194 (2009)
Glomerular visceral epithelial cells (podocytes) contain interdigitated processes that form specialized intercellular junctions, termed slit diaphragms, which provide a selective filtration barrier in the renal glomerulus. Analyses of disease-causing
Externí odkaz:
https://doaj.org/article/34963a7f651a4c7bb23169ef0133c434
Autor:
Koji Saito, Seiji Yokawa, Hidetake Kurihara, Eishin Yaoita, Sari Mizuta, Kanae Tada, Moemi Oda, Hiroyasu Hatakeyama, Yasutaka Ohta
Publikováno v:
FASEB Journal; 3/15/2024, Vol. 38 Issue 5, p1-19, 19p
Autor:
Kazuhiro Yoshikawa, Shinji Kunishima, Hidetake Kurihara, Kei Takahashi, Azumi Fukuta, Kazunori Murai, Taketora Echizenya, Izaya Nakaya, Jun Soma
Publikováno v:
Clinical Nephrology. 99:153-160
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e9ada154cbd972da5a15902099bf1b0
https://doi.org/10.5414/cn110772
https://doi.org/10.5414/cn110772
Autor:
Tomonori Hirose, Yoshinobu Sugitani, Hidetake Kurihara, Hiromi Kazama, Chiho Kusaka, Tetsuo Noda, Hidehisa Takahashi, Shigeo Ohno
Publikováno v:
Development (Cambridge, England). 149(21)
During brain development, neural precursor cells (NPCs) expand initially, and then switch to generating stage-specific neurons while maintaining self-renewal ability. Because the NPC pool at the onset of neurogenesis crucially affects the final numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ea60b2aed4e035dabfcd00dfaefaa3
https://pubmed.ncbi.nlm.nih.gov/36218069
https://pubmed.ncbi.nlm.nih.gov/36218069
Autor:
Shigeru Horita, Atsushi Tanego, Haruko Tsurumi, Kenichiro Miura, Akira Oka, Yasutaka Ohta, Takashi Igarashi, Yutaka Harita, Motoshi Hattori, Hidetake Kurihara
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
In kidney glomeruli, mesangial cells provide structural support to counteract for expansile forces caused by pressure gradients and to regulate the blood flow. Glomerular injury results in proliferation and aberrant migration of mesangial cells, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf0d43b5421cee938da1bed8565c3c8
https://doi.org/10.1038/labinvest.2015.133
https://doi.org/10.1038/labinvest.2015.133
Autor:
Masashi Mukoyama, Satoru Takahashi, Yasuhiro Yoshimura, Ryuichi Nishinakamura, Junji Yatsuda, Atsuhiro Taguchi, Hidetake Kurihara, Tomomi Kamba, Shunsuke Tanigawa
Publikováno v:
J Am Soc Nephrol
Background Previous research has elucidated the signals required to induce nephron progenitor cells (NPCs) from pluripotent stem cells (PSCs), enabling the generation of kidney organoids. However, selectively controlling differentiation of NPCs to po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf01e7e41da14cd272010f8fb0fca31
https://pubmed.ncbi.nlm.nih.gov/34969821
https://pubmed.ncbi.nlm.nih.gov/34969821
Autor:
Yasutaka Ohta, Hidetake Kurihara, Yutaka Harita, Tatsuhiro Shiino, Koji Saito, Seisuke Hattori
Publikováno v:
Cytoskeleton. 72:146-156
The function of kidney podocytes is closely associated with actin cytoskeleton. Rho family small GTPase RhoA promotes stress fiber assembly through Rho-associated protein kinase (ROCK)-dependent myosin II phosphorylation and plays an important role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::044f61575aa70b358c7f20e10f0dcc5b
https://doi.org/10.1002/cm.21211
https://doi.org/10.1002/cm.21211