Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Hideshi Ihara"'
Autor:
Takahiro Katsuki, Kayako Ogi, Ayaka Kinno, Shingo Kasamatsu, Hideshi Ihara, Hidenobu Sumitani
Publikováno v:
Foods, Vol 13, Iss 18, p 2858 (2024)
The number of people with dementia is increasing annually worldwide. Alzheimer’s disease (AD), which accounts for the highest percentage of dementia-causing diseases, remains difficult to cure, and prevention of its onset is important. We aimed to
Externí odkaz:
https://doaj.org/article/4aaec78a7b9e4e47a8fb62a66739d7cb
Autor:
Shingo Kasamatsu, Takuma Owaki, Somei Komae, Ayaka Kinno, Tomoaki Ida, Takaaki Akaike, Hideshi Ihara
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102875- (2023)
Higher consumption of broccoli (Brassica oleracea var. italica) is associated with a reduced risk of cardiometabolic diseases, neurological disorders, diabetes, and cancer. Broccoli is rich in various phytochemicals, including glucosinolates, and iso
Externí odkaz:
https://doaj.org/article/44174cd3e7a14db9bd5f9079f6689077
Autor:
Shoma Araki, Tsuyoshi Takata, Katsuhiko Ono, Tomohiro Sawa, Shingo Kasamatsu, Hideshi Ihara, Yoshito Kumagai, Takaaki Akaike, Yasuo Watanabe, Yukihiro Tsuchiya
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 9982 (2023)
Cystathionine γ-lyase (CSE) is an enzyme responsible for the biosynthesis of cysteine from cystathionine in the final step of the transsulfuration pathway. It also has β-lyase activity toward cystine, generating cysteine persulfide (Cys-SSH). The c
Externí odkaz:
https://doaj.org/article/75198ecd49074b038111f2ea4ea8155b
Publikováno v:
Antioxidants, Vol 12, Iss 5, p 1105 (2023)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder whereby oxidative stress augmentation results in mitochondrial dysfunction and cell death by apoptosis. Emerging evidence indicates that reactive sulfur species (RSS), such as glu
Externí odkaz:
https://doaj.org/article/3d60154388174d7abff0147c3a2961fd
Autor:
Eizo Marutani, Masanobu Morita, Shuichi Hirai, Shinichi Kai, Robert M. H. Grange, Yusuke Miyazaki, Fumiaki Nagashima, Lisa Traeger, Aurora Magliocca, Tomoaki Ida, Tetsuro Matsunaga, Daniel R. Flicker, Benjamin Corman, Naohiro Mori, Yumiko Yamazaki, Annabelle Batten, Rebecca Li, Tomohiro Tanaka, Takamitsu Ikeda, Akito Nakagawa, Dmitriy N. Atochin, Hideshi Ihara, Benjamin A. Olenchock, Xinggui Shen, Motohiro Nishida, Kenjiro Hanaoka, Christopher G. Kevil, Ming Xian, Donald B. Bloch, Takaaki Akaike, Allyson G. Hindle, Hozumi Motohashi, Fumito Ichinose
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
The brain is sensitive to oxygen deprivation. Here, the authors show in experimental animals that sensitivity to hypoxia is inversely related to the level of sulfide:quinone oxidoreductast (SQOR) and the capacity to catabolize sulfide in the brain.
Externí odkaz:
https://doaj.org/article/e9e4bccfec79480492fb63f03e33bd26
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2401 (2022)
2-Oxo-imidazole-containing dipeptides (2-oxo-IDPs), novel imidazole-containing dipeptide (IDP) derivatives, exhibit a much higher antioxidant capacity than that of IDPs. However, quantitative methods have only been developed for IDPs, and methods for
Externí odkaz:
https://doaj.org/article/f631a34eb4f4429eaa1afd1f9c0e7b30
Autor:
Rajalakshmi Balasubramanian, Koichi Hori, Takayuki Shimizu, Shingo Kasamatsu, Kae Okamura, Kan Tanaka, Hideshi Ihara, Shinji Masuda
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2359 (2022)
Compositions and activities of bacterial flora in the gastrointestinal tract significantly influence the metabolism, health, and disease of host humans and animals. These enteric bacteria can switch between aerobic and anaerobic growth if oxygen tens
Externí odkaz:
https://doaj.org/article/15ae9515b460483dbea4541ee4cb5cdf
Autor:
Yoshinori Ueda, Wei Zhao, Hideshi Ihara, Yoshihiro Imahori, Eleni Tsantili, Sumithra K. Wendakoon, Alan Chambers, Jinhe Bai
Publikováno v:
Foods, Vol 11, Iss 3, p 347 (2022)
Butanol vapor feeding to ripe banana pulp slices produced abundant butyl butanoate, indicating that a portion of butanol molecules was converted to butanoate/butanoyl-CoA via butanal, and further biosynthesized to ester. A similar phenomenon was obse
Externí odkaz:
https://doaj.org/article/29052308ef3a41b5baf773f1c2b8ea9f
Publikováno v:
Antioxidants, Vol 10, Iss 9, p 1434 (2021)
There is substantial evidence for the antioxidant functions of imidazole-containing dipeptides (IDPs), including carnosine and anserine, under physiological and pathological conditions in vivo. However, the detailed mechanism underlying the antioxida
Externí odkaz:
https://doaj.org/article/537ba6f86f3d4ed984157347a80fd3a9
Autor:
Takaaki Akaike, Tomoaki Ida, Fan-Yan Wei, Motohiro Nishida, Yoshito Kumagai, Md. Morshedul Alam, Hideshi Ihara, Tomohiro Sawa, Tetsuro Matsunaga, Shingo Kasamatsu, Akiyuki Nishimura, Masanobu Morita, Kazuhito Tomizawa, Akira Nishimura, Satoshi Watanabe, Kenji Inaba, Hiroshi Shima, Nobuhiro Tanuma, Minkyung Jung, Shigemoto Fujii, Yasuo Watanabe, Masaki Ohmuraya, Péter Nagy, Martin Feelisch, Jon M. Fukuto, Hozumi Motohashi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Cysteine hydropersulfides (CysSSH) are believed to have a cellular redox protective role. Here the authors show that these species can be produced from L-cysteine by cysteinyl-tRNA synthetases and that these enzymes are also involved in mitochondrial
Externí odkaz:
https://doaj.org/article/59355d393d744dc18b1812f57d180eae