Výsledky vyhledávání - "Hideshi Fujiwake"

Hierarchical Cluster and Region of Interest Analyses Based on Mass Spectrometry Imaging of Human Brain Tumours

Autor: Yuka Yajima, Norishige Yamada, Keisuke Shima, Takushi Yamamoto, Yoshiki Arakawa, Masahiro Ikegami, Yu Kakimoto, Hideshi Fujiwake, Takuya Hiratsuka, Ko-ichi Fujimoto, Tatsuaki Tsuruyama, Yuzo Yamazaki

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports

Imaging mass spectrometry (IMS) has been rarely used to examine specimens of human brain tumours. In the current study, high quality brain tumour samples were selected by tissue observation. Further, IMS analysis was combined with a new hierarchical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61ac29ca3963e982b86d03f01ccfc3e
http://link.springer.com/article/10.1038/s41598-020-62176-8

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Investigation of 5-(3-Trifluoromethylbenzylidene)thiazolidine-2,4-dione as a Matrix for Analyses of Biogenic Monoamine Transmitters Using MALDI-MS

Autor: Unno Yumi, Yuzo Yamazaki, Masayoshi Tsubuki, Tomomi Sugita, Hiroki Nakajima, Hiroko F. Kasai, Mayu Matsuoka, Hideshi Fujiwake, Masamichi Nakakoshi

Publikováno v: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 32(8)

In order to discover new matrices suitable for the analyses of low molecular-weight compounds using positive-ion mode matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry (MS), 5-(3-trifluoromethylbenzylidene)thiazolid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3000f47ff9879a0735fb2cfdc3edb6
https://pubmed.ncbi.nlm.nih.gov/27506719

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Potential Implications for Monitoring Serum Bile Acid Profiles in Circulation with Serum Proteome for Carbon Tetrachloride-Induced Liver Injury/Regeneration Model in Mice

Autor: Satoshi Yamauchi, Hideshi Fujiwake, Atsuhiro Kanzaki, Atsuhiko Toyama, Takashi Shimada, Tsuyoshi Nakanishi, Takaaki Sato, Masaya Ikegawa

Publikováno v: Journal of Proteome Research. 9:4490-4500

Bile acids have recently emerged as versatile signaling molecules, and their signaling pathway is a promising target for the treatment of metabolic diseases. Here, we developed a highly sensitive and high-throughput quantification method for six taur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916c3cc6c6847a35bad5107c742f4792
https://doi.org/10.1021/pr1002388

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Identification of inflammation-related proteins in a murine colitis model by 2D fluorescence difference gel electrophoresis and mass spectrometry

Autor: Tatsushi Omatsu, Hiroshi Ichikawa, Katsura Mizushima, Hitomi Okada, Toshikazu Yoshikawa, Tomohisa Takagi, Hideshi Fujiwake, Satoshi Kokura, Osamu Handa, Yuji Naito

Publikováno v: Journal of Gastroenterology and Hepatology. 25:S144-S148

Background and Aims: The aim of this study was to identify new intestinal proteins potentially associated with acute inflammation using proteomic profiling of an in vivo mice model of ulcerative colitis. Methods: 2D fluorescence difference gel electr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::53cc5f199af1e5894c3dd61b1617c415
https://doi.org/10.1111/j.1440-1746.2009.06219.x

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A Dye Terminator Method for Automated DNA Sequencing Using Four Fluorescent Dideoxynucleosides and Thermal Cycling

Autor: Yoshihisa Kurach, Toru Takumi, Hideshi Fujiwake

Publikováno v: Analytical Sciences. 13:735-739

Automated DNA sequencers have been developed rapidly, but dye terminator sequencing using the single-dye method remains inefficient. We have successfully established a new sequencing system using a thermostable DNA polymerase and a thermal cycling ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::78f879b3445a6e6835f1a233a3f2073f
https://doi.org/10.2116/analsci.13.735

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Identification of inflammation-related proteins in a murine colitis model by 2D fluorescence difference gel electrophoresis and mass spectrometry

Autor: Yuji, Naito, Tomohisa, Takagi, Hitomi, Okada, Tatsushi, Omatsu, Katsura, Mizushima, Osamu, Handa, Satoshi, Kokura, Hiroshi, Ichikawa, Hideshi, Fujiwake, Toshikazu, Yoshikawa

Publikováno v: Journal of gastroenterology and hepatology. 25

The aim of this study was to identify new intestinal proteins potentially associated with acute inflammation using proteomic profiling of an in vivo mice model of ulcerative colitis.2D fluorescence difference gel electrophoresis (2D-DIGE) and matrix-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::75fc3d99392b8b8db56f9f2392b6be9f
https://pubmed.ncbi.nlm.nih.gov/20586857

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