Zobrazeno 1 - 10
of 498
pro vyhledávání: '"Hideshi, Ishii"'
Autor:
Aya Hasan Alshammari, Hideshi Ishii, Takaaki Hirotsu, Hideyuki Hatakeyama, Masayo Morishita, Eric di Luccio
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Cervical cancer screening is a critical public health measure, especially vital for underserved communities where disparities in access and outcomes are pronounced. Despite the life-saving potential of regular screening, numerous barriers—including
Externí odkaz:
https://doaj.org/article/65fffc2d50144b649ac9c036a327cb4b
Autor:
Hiromichi Sato, Sikun Meng, Tomoaki Hara, Yoshiko Tsuji, Yasuko Arao, Kazuki Sasaki, Shogo Kobayashi, Eric di Luccio, Takaaki Hirotsu, Taroh Satoh, Yuichiro Doki, Hidetoshi Eguchi, Hideshi Ishii
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1342 (2024)
Gastrointestinal cancers, which include a variety of esophageal and colorectal malignancies, present a global health challenge and require effective treatment strategies. In the evolving field of cancer immunotherapy, tissue-resident memory T cells (
Externí odkaz:
https://doaj.org/article/0ee6a72de09048599fcc421fc0d0280f
Autor:
Hiromichi Sato, Tomoaki Hara, Chihiro Otsuka, Yasuko Arao, Yoshiko Tsuji, Yumiko Hamano, Mirei Ogita, Eric di Luccio, Takaaki Hirotsu, Andrea Vecchione, Hideshi Ishii
Publikováno v:
Exploration of Medicine, Vol 4, Iss 1, Pp 107-114 (2023)
m6A RNA methylation, a predominant type of RNA modification, is involved in regulating mRNA splicing, stability, and translation as well as the interaction between nucleoproteins and noncoding RNAs. Recent studies have revealed that m6A RNA methylati
Externí odkaz:
https://doaj.org/article/66895b87b39648d38e8f4bff0a352faf
Autor:
Shotaro Tatekawa, Keisuke Tamari, Ryota Chijimatsu, Masamitsu Konno, Daisuke Motooka, Suguru Mitsufuji, Hirofumi Akita, Shogo Kobayashi, Yoshiki Murakumo, Yuichiro Doki, Hidetoshi Eguchi, Hideshi Ishii, Kazuhiko Ogawa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-20 (2022)
Abstract In pancreatic cancer, methyltransferase-like 3 (METTL3), a N(6)-methyladenosine (m6A) methyltransferase, has a favorable effect on tumors and is a risk factor for patients’ prognosis. However, the details of what genes are regulated by MET
Externí odkaz:
https://doaj.org/article/7e0bd74eab3f4a91a581cff49c3255fe
Autor:
Takahito Ohshiro, Ayumu Asai, Masamitsu Konno, Mayuka Ohkawa, Yuki Komoto, Ken Ofusa, Hideshi Ishii, Masateru Taniguchi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract DNA alterations, such as base modifications and mutations, are closely related to the activity of transcription factors and the corresponding cell functions; therefore, detection of DNA alterations is important for understanding their relati
Externí odkaz:
https://doaj.org/article/46c0e21f9ef2493fa96f5ed5559db11e
Autor:
Eric di Luccio, Satoru Kaifuchi, Nobuaki Kondo, Ryota Chijimatsu, Andrea Vecchione, Takaaki Hirotsu, Hideshi Ishii
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 2, Pp 988-997 (2022)
Nematodes, such as Caenorhabditis elegans, have been instrumental to the study of cancer. Recently, their significance as powerful cancer biodiagnostic tools has emerged, but also for mechanism analysis and drug discovery. It is expected that nematod
Externí odkaz:
https://doaj.org/article/bb0e7684274a47deb80de4ea4f1fe2f7
Autor:
Hiromichi Sato, Tomoaki Hara, Shotaro Tatekawa, Kazuki Sasaki, Shogo Kobayashi, Toru Kitagawa, Yuichiro Doki, Hidetoshi Eguchi, Kazuhiko Ogawa, Shizuka Uchida, Hideshi Ishii
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
An international project on the human genome revealed that various RNAs (e.g., messenger RNAs, microRNAs, and long noncoding RNAs [lncRNAs] and their subclass circular RNA [circRNA)) are involved in the pathogenesis of different human diseases, inclu
Externí odkaz:
https://doaj.org/article/8a362c1c6ea6496f8c54d1f189def359
Autor:
Hiromichi Sato, Tomoaki Hara, Sikun Meng, Yoshiko Tsuji, Yasuko Arao, Kazuki Sasaki, Norikatsu Miyoshi, Shogo Kobayashi, Yuichiro Doki, Hidetoshi Eguchi, Hideshi Ishii
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2235 (2023)
Short non-coding RNAs, miRNAs, play roles in the control of cell growth and differentiation in cancer. Reportedly, the introduction of miRNAs could reduce the biologically malignant behavior of cancer cells, suggesting a possible use as therapeutic r
Externí odkaz:
https://doaj.org/article/b500f8066e574890bd4694d4fa29d4a0
Autor:
Takahito Ohshiro, Masamitsu Konno, Ayumu Asai, Yuki Komoto, Akira Yamagata, Yuichiro Doki, Hidetoshi Eguchi, Ken Ofusa, Masateru Taniguchi, Hideshi Ishii
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Epitranscriptomics is the study of RNA base modifications involving functionally relevant changes to the transcriptome. In recent years, epitranscriptomics has been an active area of research. However, a major issue has been the development
Externí odkaz:
https://doaj.org/article/fb68851eda5a4b55ad2abd1b0b484d75
Targeting the regulation of aberrant protein production pathway in gastrointestinal cancer treatment
Autor:
Hiromichi Sato, Kazuki Sasaki, Tomoaki Hara, Shogo Kobayashi, Yuichiro Doki, Hidetoshi Eguchi, Taroh Satoh, Hideshi Ishii
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/07aa852ded274535b723ea0c4bdc11fc