Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Hideo Tsubouchi"'
Autor:
Hideo Tsubouchi
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 662 (2023)
Homologous recombination (HR) is essential for meiosis in most sexually reproducing organisms, where it is induced upon entry into meiotic prophase. Meiotic HR is conducted by the collaborative effort of proteins responsible for DNA double-strand bre
Externí odkaz:
https://doaj.org/article/f2bbe79913fb4b93b158a5ce3de6caea
Autor:
Kentaro Ito, Yasuto Murayama, Yumiko Kurokawa, Shuji Kanamaru, Yuichi Kokabu, Takahisa Maki, Tsutomu Mikawa, Bilge Argunhan, Hideo Tsubouchi, Mitsunori Ikeguchi, Masayuki Takahashi, Hiroshi Iwasaki
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Rad51 drives DNA strand exchange, the central reaction in recombinational DNA repair. Two sites of Rad51 are responsible for DNA binding, but the function of these sites has proven elusive. Here, the authors employ real-time assays to reveal catalyti
Externí odkaz:
https://doaj.org/article/3badcf720b9b4f14b822be0b8ba4eec2
Autor:
Negar Afshar, Bilge Argunhan, Maierdan Palihati, Goki Taniguchi, Hideo Tsubouchi, Hiroshi Iwasaki
Publikováno v:
eLife, Vol 10 (2021)
Homologous recombination (HR) is essential for maintaining genome stability. Although Rad51 is the key protein that drives HR, multiple auxiliary factors interact with Rad51 to potentiate its activity. Here, we present an interdisciplinary characteri
Externí odkaz:
https://doaj.org/article/5446ec292bbc49c4a808863a3cf50121
Autor:
Bilge Argunhan, Masayoshi Sakakura, Negar Afshar, Misato Kurihara, Kentaro Ito, Takahisa Maki, Shuji Kanamaru, Yasuto Murayama, Hideo Tsubouchi, Masayuki Takahashi, Hideo Takahashi, Hiroshi Iwasaki
Publikováno v:
eLife, Vol 9 (2020)
Although Rad51 is the key protein in homologous recombination (HR), a major DNA double-strand break repair pathway, several auxiliary factors interact with Rad51 to promote productive HR. We present an interdisciplinary characterization of the intera
Externí odkaz:
https://doaj.org/article/0d52fd49954b487493dad6c30983b754
Publikováno v:
Microbial Cell, Vol 3, Iss 3, Pp 126-128 (2016)
The synaptonemal complex (SC) is a meiosis-specific chromosomal structure in which homologous chromosomes are intimately linked through arrays of specialized proteins called transverse filaments (TF). Widely conserved in eukaryote meiosis, the SC for
Externí odkaz:
https://doaj.org/article/693fd091c00e4e19828ef264fc573861
Autor:
Neil Humphryes, Wing-Kit Leung, Bilge Argunhan, Yaroslav Terentyev, Martina Dvorackova, Hideo Tsubouchi
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003194 (2013)
During meiosis, homologous chromosomes pair at close proximity to form the synaptonemal complex (SC). This association is mediated by transverse filament proteins that hold the axes of homologous chromosomes together along their entire length. Transv
Externí odkaz:
https://doaj.org/article/5d53d94a4e1f4a9b889307a19f10c6ce
Autor:
Karen Voelkel-Meiman, Louis F Taylor, Pritam Mukherjee, Neil Humphryes, Hideo Tsubouchi, Amy J Macqueen
Publikováno v:
PLoS Genetics, Vol 9, Iss 10, p e1003837 (2013)
The synaptonemal complex (SC) is a widely conserved structure that mediates the intimate alignment of homologous chromosomes during meiotic prophase and is required for proper homolog segregation at meiosis I. However, fundamental details of SC archi
Externí odkaz:
https://doaj.org/article/f4972927d641469488b76ca1f03514f9
Autor:
Bilge Argunhan, Sarah Farmer, Wing-Kit Leung, Yaroslav Terentyev, Neil Humphryes, Tomomi Tsubouchi, Hiroshi Toyoizumi, Hideo Tsubouchi
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65875 (2013)
Meiotic recombination plays an essential role in the proper segregation of chromosomes at meiosis I in many sexually reproducing organisms. Meiotic recombination is initiated by the scheduled formation of genome-wide DNA double-strand breaks (DSBs).
Externí odkaz:
https://doaj.org/article/080c5430a0214f34915880afabff701b
Autor:
Sarah Farmer, Eun-Jin Erica Hong, Wing-Kit Leung, Bilge Argunhan, Yaroslav Terentyev, Neil Humphryes, Hiroshi Toyoizumi, Hideo Tsubouchi
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39724 (2012)
Budding yeast Pch2 protein is a widely conserved meiosis-specific protein whose role is implicated in the control of formation and displacement of meiotic crossover events. In contrast to previous studies where the function of Pch2 was implicated in
Externí odkaz:
https://doaj.org/article/ac797ae5b34447bd944501e558b75e2f
Autor:
Sarah Farmer, Eun-Jin Erica Hong, Wing-Kit Leung, Bilge Argunhan, Yaroslav Terentyev, Neil Humphryes, Hiroshi Toyoizumi, Hideo Tsubouchi
Publikováno v:
PLoS ONE, Vol 7, Iss 10 (2012)
Externí odkaz:
https://doaj.org/article/0ec5f91fa42e4421b6e40c3d9c1a720d