Zobrazeno 1 - 10
of 280
pro vyhledávání: '"Hideo Higuchi"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Dynein is a minus-end-directed motor that generates oscillatory motion in eukaryotic flagella. Cyclic beating, which is the most significant feature of a flagellum, occurs by sliding spatiotemporal regulation by dynein along microtubules. To
Externí odkaz:
https://doaj.org/article/c645c68b44524f10addd7a5413f7b69f
Autor:
Shimaa A Abdellatef, Hisashi Tadakuma, Kangmin Yan, Takashi Fujiwara, Kodai Fukumoto, Yuichi Kondo, Hiroko Takazaki, Rofia Boudria, Takuo Yasunaga, Hideo Higuchi, Keiko Hirose
Publikováno v:
eLife, Vol 11 (2022)
Bending of cilia and flagella occurs when axonemal dynein molecules on one side of the axoneme produce force and move toward the microtubule (MT) minus end. These dyneins are then pulled back when the axoneme bends in the other direction, meaning osc
Externí odkaz:
https://doaj.org/article/bd6d030985354524a30d9721b459c627
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract The heart rhythm is maintained by oscillatory changes in [Ca2+]. However, it has been suggested that the rapid drop in blood pressure that occurs with a slow decrease in [Ca2+] preceding early diastolic filling is related to the mechanism of
Externí odkaz:
https://doaj.org/article/75cbc6b6536c4aa6a0c62c35a9726143
Autor:
Kohsuke Gonda, Hiroshi Negishi, Mayumi Takano-Kasuya, Narufumi Kitamura, Naoko Furusawa, Yasushi Nakano, Yoh Hamada, Masayuki Tokunaga, Hideo Higuchi, Hiroshi Tada, Takanori Ishida
Publikováno v:
Translational Oncology, Vol 13, Iss 6, Pp - (2020)
Anticancer drug efficacy varies because the delivery of drugs within tumors and tumor responses are heterogeneous; however, these features are often more homogenous in vitro. This difference makes it difficult to accurately determine drug efficacy. T
Externí odkaz:
https://doaj.org/article/81077d0174924a788743ae7f605b75bd
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Skeletal muscle myosin forms large ensembles to generate force against high loads. Using optical tweezers and simulation Kayaet al. provide experimental evidence for cooperative force generation, and describe how the molecular properties of skeletal
Externí odkaz:
https://doaj.org/article/ce3987606aff4fb0bbb5abd6897b3bf8
Publikováno v:
Sensors, Vol 21, Iss 2, p 522 (2021)
Elucidation of cell-level transport mediated by vesicles within a living cell provides key information regarding viral infection processes and also drug delivery mechanisms. Although the single-particle tracking method has enabled clear analysis of i
Externí odkaz:
https://doaj.org/article/0ffc19ce1f6c4dfbb29576ee3ae5fdbe
Publikováno v:
Science and Technology of Advanced Materials, Vol 17, Iss 1, Pp 473-482 (2016)
The processes involved in malignant gliomas damage were quantitatively evaluated by microscopy. The near-infrared fluorescent dye IR700 that is conjugated to an anti-CD133 antibody (IR700-CD133) specifically targets malignant gliomas (U87MG) and stem
Externí odkaz:
https://doaj.org/article/12ff93f4597f46c99a573b066988863b
Publikováno v:
Applied Sciences, Vol 10, Iss 18, p 6243 (2020)
Imaging the three-dimensional movement of small organelles in living cells can provide key information for the dynamics of drug delivery and virus transmission in biomedical disciplines. To stably monitor such intracellular motion using microscope, l
Externí odkaz:
https://doaj.org/article/4683a1c484f045fd98ec64ae3a94f363
Autor:
Ryoma Nakao, Kenji Kikushima, Hideo Higuchi, Nozomu Obana, Nobuhiko Nomura, Dongying Bai, Makoto Ohnishi, Hidenobu Senpuku
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e95137 (2014)
Membrane vesicles (MVs) of Porphyromonas gingivalis are regarded as an offensive weapon of the bacterium, leading to tissue deterioration in periodontal disease. Therefore, isolation of highly purified MVs is indispensable to better understand the pa
Externí odkaz:
https://doaj.org/article/c553f783ea0742598a49ce69f4c4d180
Publikováno v:
Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXX.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9778d9a26238a3b9d32b65ec5a696a29
https://doi.org/10.1117/12.2649474
https://doi.org/10.1117/12.2649474