Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Hideo, Yasukawa"'
Autor:
Mai Yamamoto, Hideo Yasukawa, Jinya Takahashi, Shoichiro Nohara, Tomoko Sasaki, Kodai Shibao, Daiki Akagaki, Kota Okabe, Toshiyuki Yanai, Tatsuhiro Shibata, Yoshihiro Fukumoto
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0286907 (2023)
Myocardial infarction (MI) can result in fatal myocardial rupture or heart failure due to adverse remodeling and dysfunction of the left ventricle. Although recent studies have shown that exogenous interleukin (IL)-22 shows cardioprotective effect af
Externí odkaz:
https://doaj.org/article/ca0854f905b343d88d4c89cd67035208
Autor:
Saki Hirakata, MD, Hiroki Aoki, MD, PhD, Satoko Ohno-Urabe, MD, PhD, Michihide Nishihara, MD, PhD, Aya Furusho, MD, PhD, Norifumi Nishida, MD, Sohei Ito, MD, Makiko Hayashi, MD, Hideo Yasukawa, MD, PhD, Tsutomu Imaizumi, MD, PhD, Sinichi Hiromatsu, MD, PhD, Hiroyuki Tanaka, MD, PhD, Yoshihiro Fukumoto, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 5, Iss 2, Pp 126-144 (2020)
Summary: Aortic dissection (AD) is the acute destruction of aortic wall and is reportedly induced by inflammatory response. Here we investigated the role of smooth muscle Socs3 (a negative regulator of Janus kinases/signal transducer and activator of
Externí odkaz:
https://doaj.org/article/83a8bf407ee34e8189a3a5b7ac49083d
Autor:
Shoichiro Nohara, Mai Yamamoto, Hideo Yasukawa, Takanobu Nagata, Jinya Takahashi, Koutatsu Shimozono, Toshiyuki Yanai, Tomoko Sasaki, Kota Okabe, Tatsuhiro Shibata, Daiki Akagaki, Kazutoshi Mawatari, Yoshihiro Fukumoto
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254712 (2021)
Ischemic preconditioning (IPC) is the most powerful endogenous cardioprotective form of cellular adaptation. However, the inhibitory or augmenting mechanism underlying cardioprotection via IPC remains largely unknown. Suppressor of cytokine signaling
Externí odkaz:
https://doaj.org/article/4f80687e6dd540a3a793ca38f9088e8e
Autor:
Jinya Takahashi, Mai Yamamoto, Hideo Yasukawa, Shoichiro Nohara, Takanobu Nagata, Koutatsu Shimozono, Toshiyuki Yanai, Tomoko Sasaki, Kota Okabe, Tatsuhiro Shibata, Kazutoshi Mawatari, Tatsuyuki Kakuma, Hiroki Aoki, Yoshihiro Fukumoto
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 8 (2020)
BACKGROUND Interleukin (IL)‐22, a member of the IL‐10 cytokine family, is the only known cytokine that is secreted by immune cells but does not target immune cells; it mainly targets epithelial cells. In this study, we aimed to determine whether
Externí odkaz:
https://doaj.org/article/3ac5dc9d8b1043b88815243023092557
Autor:
Satoko Ohno‐Urabe, Hiroki Aoki, Michihide Nishihara, Aya Furusho, Saki Hirakata, Norifumi Nishida, Sohei Ito, Makiko Hayashi, Hideo Yasukawa, Tsutomu Imaizumi, Hidetoshi Akashi, Hiroyuki Tanaka, Yoshihiro Fukumoto
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 2 (2018)
BackgroundAortic dissection (AD) is a life‐threatening medical emergency caused by the abrupt destruction of the intimomedial layer of the aortic walls. Given that previous studies have reported the involvement of proinflammatory cytokine interleuk
Externí odkaz:
https://doaj.org/article/cd499ab5c5b544cfb1f158a739decd87
Autor:
Hiroyuki Tanaka, Satoko Ohno-Urabe, Hiroki Aoki, Tsutomu Imaizumi, Sinichi Hiromatsu, Saki Hirakata, Makiko Hayashi, Yoshihiro Fukumoto, Sohei Ito, Aya Furusho, Norifumi Nishida, Michihide Nishihara, Hideo Yasukawa
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 5, Iss 2, Pp 126-144 (2020)
JACC: Basic to Translational Science, Vol 5, Iss 2, Pp 126-144 (2020)
Summary: Aortic dissection (AD) is the acute destruction of aortic wall and is reportedly induced by inflammatory response. Here we investigated the role of smooth muscle Socs3 (a negative regulator of Janus kinases/signal transducer and activator of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e0c46afd4f4d1a9d0e7f16e9c345a8
https://doi.org/10.1016/j.jacbts.2019.10.010
https://doi.org/10.1016/j.jacbts.2019.10.010
Autor:
Mai Yamamoto, Hideo Yasukawa, Jinya Takahashi, Shoichiro Nohara, Tomoko Minami, Tatsuhiro Shibata, Toshiyuki Yanai, Kota Okabe, Daiki Akagaki, Yoshihiro Fukumoto
Publikováno v:
Circulation. 144
Introduction: Interleukin-22 (IL-22) is a member of the IL-10 cytokine family, which promotes STAT3 activation in targets cells. Although it has been shown that persistent activation of STAT3 causes myocardial hypertrophy and fibrosis, little is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::375db61de773a9570abb9c3601e9a39f
https://doi.org/10.1161/circ.144.suppl_1.13647
https://doi.org/10.1161/circ.144.suppl_1.13647
Autor:
Takanobu Nagata, Hideo Yasukawa, Sachiko Kyogoku, Toyoharu Oba, Jinya Takahashi, Shoichiro Nohara, Tomoko Minami, Kazutoshi Mawatari, Yusuke Sugi, Koutatsu Shimozono, Sylvain Pradervand, Masahiko Hoshijima, Hiroki Aoki, Yoshihiro Fukumoto, Tsutomu Imaizumi
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127942 (2015)
Myocardial ischemia reperfusion injury (IRI) adversely affects cardiac performance and the prognosis of patients with acute myocardial infarction. Although myocardial signal transducer and activator of transcription (STAT) 3 is potently cardioprotect
Externí odkaz:
https://doaj.org/article/8d05709fc4874091845e44d11e40e62e
Autor:
Kota Okabe, Kazutoshi Mawatari, Hideo Yasukawa, Jinya Takahashi, Mai Yamamoto, T Sasaki, Shoichiro Nohara, Koutatsu Shimozono, Toshiyuki Yanai, Yoshihiro Fukumoto, Takanobu Nagata, Daiki Akagaki, Tatsuhiro Shibata
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254712 (2021)
PLoS ONE
PLoS ONE
Ischemic preconditioning (IPC) is the most powerful endogenous cardioprotective form of cellular adaptation. However, the inhibitory or augmenting mechanism underlying cardioprotection via IPC remains largely unknown. Suppressor of cytokine signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a7069e6d72e885551666f4f05f8393
https://doaj.org/article/4f80687e6dd540a3a793ca38f9088e8e
https://doaj.org/article/4f80687e6dd540a3a793ca38f9088e8e
Autor:
Koutatsu Shimozono, T Sasaki, Jinya Takahashi, Mai Yamamoto, Tatsuhiro Shibata, Yoshihiro Fukumoto, Shoichiro Nohara, K Okabe, Toshiyuki Yanai, Hideo Yasukawa, Kazutoshi Mawatari
Publikováno v:
European Heart Journal. 41
Background Suppressor of cytokine signaling-3 (SOCS3) is a cytokine-inducible negative regulator of signal transducer and activator of transcription-3 (STAT3) signaling pathway. We have previously shown that cardiac-specific SOCS3 deficiency spontane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c28c738ae574594eb2d6fcfd7e861392
https://doi.org/10.1093/ehjci/ehaa946.3742
https://doi.org/10.1093/ehjci/ehaa946.3742