Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Hideo, Tsukamoto"'
Autor:
Nobuo Watanabe, Masako Kidokoro, Yusuke Suzuki, Makiko Tanaka, Shigeaki Inoue, Hideo Tsukamoto, Noriaki Hirayama, Pei-Wen Hsieh, Ching-Ping Tseng, Yoshihide Nakagawa, Sadaki Inokuchi
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222331 (2019)
Podoplanin, a transmembrane glycoprotein, is overexpressed in certain types of tumors and induces platelet aggregation by binding to C-type lectin-like receptor 2 (CLEC-2) on the platelet membrane. Activated platelets release granule components, whic
Externí odkaz:
https://doaj.org/article/c54fab57e9d14e70b7d85211ec6bb248
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190620 (2018)
Migraine attacks alter various molecules that might be related to the pathophysiology of migraine, such as serotonin, calcitonin gene-related peptide, and nitric oxide. The underlying pathophysiology of migraine is as yet unclear. We explored key pro
Externí odkaz:
https://doaj.org/article/baad84ceb1834358a23baf112fad05f5
Autor:
Masanobu Yoshikawa, Takashi Shinomiya, Naoko Takayasu, Hideo Tsukamoto, Mitsuru Kawaguchi, Hiroyuki Kobayashi, Tetsuo Oka, Atsushi Hashimoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 107, Iss 3, Pp 270-276 (2008)
Recent studies indicate that an endogenous co-agonist for an N-methyl-D-aspartate (NMDA) receptor–related glycine site, D-serine, is synthesized by serine racemase and is metabolized by D-amino acid oxidase (DAO) and that acute treatment with morph
Externí odkaz:
https://doaj.org/article/7d97cd9ead854dfc972f76f34789ce8f
Autor:
Akane Kondo, Junko Inagaki, Kazuko Kobayashi, Hideo Tsukamoto, Daisuke Yamamoto, Mikiya Nakatsuka, Nobuharu Suzuki, Motoyoshi Nomizu, Satoshi Amano, Hidehiko Matsubayashi, Tatsuji Yasuda, Luis R. Lopez, Yehuda Shoenfeld, Tsunehisa Makino, Eiji Matsuura
Publikováno v:
Clinical and Developmental Immunology, Vol 12, Iss 1, Pp 67-73 (2005)
Laminin-1 is a structural glycoprotein that forms an integral part of the scaffolding of basement membranes, and plays an important role during embryonic development. We have recently demonstrated a significant association between anti-laminin-1 anti
Externí odkaz:
https://doaj.org/article/34fc99db475a4978ac5a28ec2404ddfe
Autor:
Chisa Okada, Ayumi Sasaki, Yu Kakimoto, Hideo Tsukamoto, Ryoko Nagao, Noboru Kawabe, Motoki Osawa
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports
Lipofuscin is an intracellular aggregate of highly oxidized proteins that cannot be digested in the ubiquitin-proteasome system and accumulate mainly in lysosomes, especially in aged cells and pathological conditions. However, no systematic study has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc723c39c407782a38893d9c3262c74f
http://link.springer.com/article/10.1038/s41598-019-40250-0
http://link.springer.com/article/10.1038/s41598-019-40250-0
Autor:
Eiichiro Nagata, Natsuko Fujii, Kazuyoshi Hosomichi, Shigeki Mitsunaga, Yoichi Suzuki, Yoichi Mashimo, Hideo Tsukamoto, Tadayuki Satoh, Motoki Osawa, Ituro Inoue, Akira Hata, Shunya Takizawa
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105319 (2014)
To identify the genetic causality of migraine and acute, severe melalgia, we performed a linkage analysis and exome sequencing in a family with four affected individuals. We identified a variant (R21L) in exon 2 of the GC globulin gene, which is invo
Externí odkaz:
https://doaj.org/article/f9f6bf6d7591473797c40863b7935963
Publikováno v:
Journal of Bioactive and Compatible Polymers. 33:498-515
Poly(2-methoxyethyl acrylate) is known to exhibit good blood compatibility. This study was designed to understand the effect of methoxyethyl ester groups on the platelet compatibility of polymers. Polymers bearing either methoxyethyl ester or methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd482fab21c6032507df3ed8eed24feb
https://doi.org/10.1177/0883911518793917
https://doi.org/10.1177/0883911518793917
Autor:
Yasuhiro Fujino, Kanae Umemoto, Masatoshi Ito, Masayuki Tatemichi, Hayato Terayama, Ning Qu, Kou Sakabe, Hideo Tsukamoto, Hitoshi Endo, Satoshi Kawakami
Publikováno v:
International journal of environmental health research. 28(6)
Neonicotinoids, such as acetamiprid (ACE), a pesticide used worldwide, are believed to be safe for human use. These molecules are structurally similar to nicotine, act as nicotinic acetylcholine receptor (nAChR) agonists, and were shown to be associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca327772d9f0a36fdbc166da289c595
https://pubmed.ncbi.nlm.nih.gov/30103633
https://pubmed.ncbi.nlm.nih.gov/30103633
Autor:
Yin Sheng, Yoshiaki Ogawa, Hiromichi Matsushita, Hideo Tsukamoto, Hideyuki Matsuzawa, Mitsuyo Tsuma-Kaneko, Hidetsugu Kawai, Kiyoshi Ando, Hiroshi Kawada, Rikio Suzuki, Jun Lu, Takashi Yahata
Publikováno v:
Leukemia Research. 38:1451-1459
We analyzed the function of a SEPT9-ABL1 fusion identified in a case of T-prolymphocytic leukemia with tyrosine kinase inhibitor (TKI) resistance. Five isoforms with different N-termini, including SEPT9a-ABL1, SEPT9b-ABL1, SEPT9d-ABL1, SEPT9e-ABL1 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e946794e4a74d39db17ca68f7579be4
https://doi.org/10.1016/j.leukres.2014.08.015
https://doi.org/10.1016/j.leukres.2014.08.015
Autor:
Takafumi Watanabe, Takuya Kinoshita, Akira Mochizuki, Chihiro Fukuda, Chie Yahata, Hideo Tsukamoto
It is well known that polyether-based copolymers have good blood compatibility, although many mechanisms have been proposed to explain their favorable performance. Our objective in carrying out the present study was to obtain a better understanding o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726833653d352d89fc852ea0b109d58f
