Zobrazeno 1 - 10
of 469
pro vyhledávání: '"Hideo, Saji"'
Autor:
Takaaki Murakami, Hiroyuki Fujimoto, Keita Hamamatsu, Yuki Yamauchi, Yuzo Kodama, Naotaka Fujita, Junji Fujikura, Yoichi Shimizu, Yuji Nakamoto, Hiroyuki Kimura, Hideo Saji, Nobuya Inagaki
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Specifying the exact localization of insulinoma remains challenging due to the lack of insulinoma-specific imaging methods. Recently, glucagon-like peptide-1 receptor (GLP-1R)-targeted imaging, especially positron emission tomography (PET),
Externí odkaz:
https://doaj.org/article/eb79b0bd544f428e86385fa7f2a8e030
Autor:
Yoichi Shimizu, Yukihiro Nakai, Hiroyuki Watanabe, Shimpei Iikuni, Masahiro Ono, Hideo Saji, Yuji Kuge, Tsuneo Saga, Yuji Nakamoto
Publikováno v:
EJNMMI Research, Vol 11, Iss 1, Pp 1-6 (2021)
Abstract Background [18F]Fluoromisonidazole ([18F]FMISO) is a PET imaging probe widely used for the detection of hypoxia. We previously reported that [18F]FMISO is metabolized to the glutathione conjugate of the reduced form in hypoxic cells. In addi
Externí odkaz:
https://doaj.org/article/a168680e57f44defada50db1f8196656
Autor:
Hiroyuki Fujimoto, Naotaka Fujita, Keita Hamamatsu, Takaaki Murakami, Yuji Nakamoto, Tsuneo Saga, Takayoshi Ishimori, Yoichi Shimizu, Hiroyuki Watanabe, Kohei Sano, Norio Harada, Hiroshi Nakamura, Kentaro Toyoda, Hiroyuki Kimura, Shunsaku Nakagawa, Mitsuharu Hirai, Atsushi Murakami, Masahiro Ono, Kaori Togashi, Hideo Saji, Nobuya Inagaki
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Pancreatic β-cell mass (BCM) has a central importance in the pathophysiology of diabetes mellitus. Recently, pancreatic β-cell-specific imaging, especially positron emission tomography (PET) with exendin-based probes, has emerged for non-invasive e
Externí odkaz:
https://doaj.org/article/d3b5de91dba247f7b39b785890233ef5
Autor:
Mitsuharu Kimura, Ibuki Onishi, Yumi Yamamoto, Yohei Saito, Hiroshi Fukuda, Akira Makino, Yasushi Kiyono, Hideo Saji, Eiichi Ozeki, Shunsaku Kimura, Fumihiko Yamamoto
Publikováno v:
RADIOISOTOPES. 72:149-161
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfeb1c05852467f881a3c32c6f48e855
https://doi.org/10.3769/radioisotopes.72.149
https://doi.org/10.3769/radioisotopes.72.149
Autor:
Hiroyuki Ikeda, Akira Ishii, Kohei Sano, Hideo Chihara, Daisuke Arai, Yu Abekura, Hidehisa Nishi, Masahiro Ono, Hideo Saji, Susumu Miyamoto
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Background and PurposeChronic inflammation is involved in the formation and enlargement of cerebral aneurysms (CAs), with macrophages playing a key role in the process. The present study evaluated visualization of macrophages present in CAs using an
Externí odkaz:
https://doaj.org/article/5f81ed8695a943ed91b6efe06c8a39c5
Publikováno v:
Molecules, Vol 27, Iss 4, p 1287 (2022)
Zinc is an essential trace element involved in many biological activities; however, its functions are not fully understood. To elucidate the role of endogenous labile Zn2+, we developed a novel ratiometric fluorescence probe, 5-(4-methoxyphenyl)-4-(m
Externí odkaz:
https://doaj.org/article/ba00a882bb884da1931e87c5ae0d7281
Autor:
Masahiro Ono, Hiroyuki Watanabe, Yuki Ikehata, Ning Ding, Masashi Yoshimura, Kohei Sano, Hideo Saji
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract In molecular imaging research, the development of multimodal imaging probes has recently attracted much attention. In the present study, we prepared radioiodinated BODIPY and applied it as a nuclear and optical dual functional labeling agent
Externí odkaz:
https://doaj.org/article/4bb433f28be64b8480da9b9d40c00e90
Autor:
Yuji Nakamoto, Hiroyuki Kimura, Junji Fujikura, Keita Hamamatsu, Naotaka Fujita, Hiroyuki Fujimoto, Yuki Yamauchi, Takaaki Murakami, Hideo Saji, Yuzo Kodama, Nobuya Inagaki, Yoichi Shimizu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Specifying the exact localization of insulinoma remains challenging due to the lack of insulinoma-specific imaging methods. Recently, glucagon-like peptide-1 receptor (GLP-1R)-targeted imaging, especially positron emission tomography (PET), has emerg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738dd0793745b70b8ea542a0e1bbe486
https://doaj.org/article/eb79b0bd544f428e86385fa7f2a8e030
https://doaj.org/article/eb79b0bd544f428e86385fa7f2a8e030
Autor:
Yoichi Shimizu, Keiichi Tanimura, Shimpei Iikuni, Hiroyuki Watanabe, Hideo Saji, Masahiro Ono
Publikováno v:
Molecules, Vol 24, Iss 12, p 2283 (2019)
Hyperlipidemia causes systemic lipid disorder, which leads to hepatic steatosis and atherosclerosis. Thus, it is necessary to detect these syndromes early and precisely to improve prognosis. In the affected regions, abnormal formation and growth of l
Externí odkaz:
https://doaj.org/article/4b71b2c17bc6494fa5e351362709e569
Autor:
Masayori Hagimori, Mana Taniura, Naoko Mizuyama, Yasushi Karimine, Shigeru Kawakami, Hideo Saji, Takahiro Mukai
Publikováno v:
Sensors, Vol 19, Iss 9, p 2049 (2019)
A small extent of endogenous labile zinc is involved in many vital physiological roles in living systems. However, its detailed functions have not been fully elucidated. In this study, we developed a novel biheteroaryl-based low molecular weight fluo
Externí odkaz:
https://doaj.org/article/241996374d23494ba846fc117fe09657