Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Hidenori Kitai"'
Autor:
Hidenori Kitai, Philip H. Choi, Yu C. Yang, Jacob A. Boyer, Adele Whaley, Priya Pancholi, Claire Thant, Jason Reiter, Kevin Chen, Vladimir Markov, Hirokazu Taniguchi, Rui Yamaguchi, Hiromichi Ebi, James Evans, Jingjing Jiang, Bianca Lee, David Wildes, Elisa de Stanchina, Jacqueline A. M. Smith, Mallika Singh, Neal Rosen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Current KRASG12C (OFF) inhibitors that target inactive GDP-bound KRASG12C cause responses in less than half of patients and these responses are not durable. A class of RASG12C (ON) inhibitors that targets active GTP-bound KRASG12C blocks ERK
Externí odkaz:
https://doaj.org/article/7ad6de68f66945a2a3cb9c50ceaaf9b5
Autor:
Hirokazu Taniguchi, Rebecca Caeser, Shweta S. Chavan, Yingqian A. Zhan, Andrew Chow, Parvathy Manoj, Fathema Uddin, Hidenori Kitai, Rui Qu, Omar Hayatt, Nisargbhai S. Shah, Álvaro Quintanal Villalonga, Viola Allaj, Evelyn M. Nguyen, Joseph Chan, Adam O. Michel, Hiroshi Mukae, Elisa de Stanchina, Charles M. Rudin, Triparna Sen
Publikováno v:
Cell Reports, Vol 39, Iss 7, Pp 110814- (2022)
Summary: Small cell lung cancers (SCLCs) have high mutational burden but are relatively unresponsive to immune checkpoint blockade (ICB). Using SCLC models, we demonstrate that inhibition of WEE1, a G2/M checkpoint regulator induced by DNA damage, ac
Externí odkaz:
https://doaj.org/article/ab09d4c714e64f25a536b12f1cde0a86
Autor:
Yuka Suimon, Wataru Saito, Kiriko Hirooka, Atsuhiro Kanda, Hidenori Kitai, Jun Sakakibara-Konishi, Susumu Ishida
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 5, Iss C, Pp 137-140 (2017)
Purpose: To report an anti-recoverin antibody-positive cancer-associated retinopathy (anti-recoverin CAR) patient with remarkable improvements of visual function and outer retinal morphology following spontaneous regression of cancer. Observations: A
Externí odkaz:
https://doaj.org/article/68f981a263e4451a9afa609a2e071acd
Publikováno v:
The Journal of The Institute of Electrical Engineers of Japan. 142:758-761
Autor:
Anthony C. Faber, Jeffrey A. Engelman, Hiromichi Ebi, Bradley Bernstein, Lecia V. Sequist, Mikhail Dozmorov, Shirley M. Taylor, Sinem E. Sahingur, Zofia Piotrowska, Brad E. Windle, Tara J. Nulton, Maria Gomez-Caraballo, Hannah L. Archibald, Shawn Gillepsie, Angel Garcia, Elizabeth L. Lockerman, Neha U. Patel, Mark T. Hughes, Daniel A.R. Heisey, Yotam Drier, Hillary E. Mulvey, Haichuan Hu, Mark A. Hicks, Konstantinos V. Floros, Jungoh Ham, Hidenori Kitai, Aaron N. Hata, Timothy L. Lochmann, Matthew J. Niederst, Kyung-A Song
Supplemental legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cdf55fda2d52240554b29e627d0a09c
https://doi.org/10.1158/1078-0432.22462238
https://doi.org/10.1158/1078-0432.22462238
Autor:
Anthony C. Faber, Jeffrey A. Engelman, Hiromichi Ebi, Bradley Bernstein, Lecia V. Sequist, Mikhail Dozmorov, Shirley M. Taylor, Sinem E. Sahingur, Zofia Piotrowska, Brad E. Windle, Tara J. Nulton, Maria Gomez-Caraballo, Hannah L. Archibald, Shawn Gillepsie, Angel Garcia, Elizabeth L. Lockerman, Neha U. Patel, Mark T. Hughes, Daniel A.R. Heisey, Yotam Drier, Hillary E. Mulvey, Haichuan Hu, Mark A. Hicks, Konstantinos V. Floros, Jungoh Ham, Hidenori Kitai, Aaron N. Hata, Timothy L. Lochmann, Matthew J. Niederst, Kyung-A Song
ZEB1 binding sites found in 1975R2 cells compared to 1975 parental cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a27042f9ca1b22d872df72208f56c4
https://doi.org/10.1158/1078-0432.22462241
https://doi.org/10.1158/1078-0432.22462241
Autor:
Anthony C. Faber, Jeffrey A. Engelman, Hiromichi Ebi, Bradley Bernstein, Lecia V. Sequist, Mikhail Dozmorov, Shirley M. Taylor, Sinem E. Sahingur, Zofia Piotrowska, Brad E. Windle, Tara J. Nulton, Maria Gomez-Caraballo, Hannah L. Archibald, Shawn Gillepsie, Angel Garcia, Elizabeth L. Lockerman, Neha U. Patel, Mark T. Hughes, Daniel A.R. Heisey, Yotam Drier, Hillary E. Mulvey, Haichuan Hu, Mark A. Hicks, Konstantinos V. Floros, Jungoh Ham, Hidenori Kitai, Aaron N. Hata, Timothy L. Lochmann, Matthew J. Niederst, Kyung-A Song
Top 10 correlated genes to BIM (BCL2L11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28634790899e5554faee70782d605662
https://doi.org/10.1158/1078-0432.22462244.v1
https://doi.org/10.1158/1078-0432.22462244.v1
Autor:
Anthony C. Faber, Jeffrey A. Engelman, Hiromichi Ebi, Bradley Bernstein, Lecia V. Sequist, Mikhail Dozmorov, Shirley M. Taylor, Sinem E. Sahingur, Zofia Piotrowska, Brad E. Windle, Tara J. Nulton, Maria Gomez-Caraballo, Hannah L. Archibald, Shawn Gillepsie, Angel Garcia, Elizabeth L. Lockerman, Neha U. Patel, Mark T. Hughes, Daniel A.R. Heisey, Yotam Drier, Hillary E. Mulvey, Haichuan Hu, Mark A. Hicks, Konstantinos V. Floros, Jungoh Ham, Hidenori Kitai, Aaron N. Hata, Timothy L. Lochmann, Matthew J. Niederst, Kyung-A Song
Purpose: Epithelial-to-mesenchymal transition (EMT) confers resistance to a number of targeted therapies and chemotherapies. However, it has been unclear why EMT promotes resistance, thereby impairing progress to overcome it.Experimental Design: We h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2dd5859ffe827d68fb39cfaad05bff
https://doi.org/10.1158/1078-0432.c.6525047.v1
https://doi.org/10.1158/1078-0432.c.6525047.v1
Autor:
Hidenori Kitai, Hisato Michikoshi, Kunihiro Sakamoto, Akira Tokuchi, Tatsuya Kaito, Ken Takayama, Katsuya Okamura, Daiki Kumamoto, Fujio Naito
Publikováno v:
Materials Science Forum. 1004:1141-1147
To resolve the drawback of conventional thyratron switches, development of a semiconductor high voltage switch utilizing a 13 kV class SiC-MOSFET developed by Tsukuba Power Electronics Constellations (TPEC) is proceeding. At first, the device evaluat
Autor:
Shingo Matsumoto, Ryohei Yoshida, Naofumi Shinagawa, Hidenori Mizugaki, Shinichi Chiba, Yutaka Hatanaka, Hidenori Kitai, Yasuyuki Ikezawa, Jun Sakakibara-Konishi, Takaaki Sasaki, Koichi Goto
Publikováno v:
Clinical lung cancer. 20(5):E555-E559