Výsledky vyhledávání - "Hidenori Hayashida"

The Complete Nucleotide Sequence of the Human Immunoglobulin Heavy Chain Variable Region Locus

Autor: Patrice Bourvagnet, Hidenori Hayashida, Fumihiko Matsuda, Tasuku Honjo, Kei-ichi Kuma, Kazuo Ishii, Takashi Miyata

Publikováno v: The Journal of Experimental Medicine

The complete nucleotide sequence of the 957-kb DNA of the human immunoglobulin heavy chain variable (VH) region locus was determined and 43 novel VH segments were identified. The region contains 123 VH segments classifiable into seven different famil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e036db0ef5d59cab4c91fb0ae1578ee6
http://europepmc.org/articles/PMC2212390

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Comparison and evolution of human immunoglobulin VH segments located in the 3' 0.8-megabase region. Evidence for unidirectional transfer of segmental gene sequences

Autor: Takashi Miyata, Yosho Fukita, Ryusuke Matsumura, Hitoshi Nagaoka, Junji Fujikura, Makoto Haino, Shigeo Takaishi, Hidenori Hayashida, Euy Kyun Shin, Fumihiko Matsuda

Publikováno v: Journal of Biological Chemistry. 269:2619-2626

Nucleotide sequences of 64 VH segments within the 3' 0.8-megabase region of the human immunoglobulin germ line VH locus were compared with trace evolution of human VH segments. Based on alignment of the deduced amino acid sequences of 37 functional g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2eeb069290edb630ae4ecf3897627bd
https://doi.org/10.1016/s0021-9258(17)41989-2

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Recent translocation of variable and diversity segments of the human immunoglobulin heavy chain from chromosome 14 to chromosomes 15 and 16

Autor: Yosho Fukita, Rakesh Anand, Kazushige Yokoyama, Takashi Imai, Ryusuke Matsumura, Hidenori Hayashida, Euy Kyun Shin, Eiichi Soeda, Toshihiko Eki, Fumihiko Matsuda, Makoto Haino, Tasuku Honjo, Kazuo Ozawa, Hitoshi Nagaoka

Publikováno v: Genomics. 22(1)

The authors studied the organization and origin of three orphon regions, V{sub H-F}, D{sub 5-a}, and D{sub 5-b}, of the human immunoglobulin heavy-chain gene using yeast artificial chromosomes. V{sub H-F} and two D{sub 5} regions were mapped to chrom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76169cb5f1385b42ea86a98160be807c
https://pubmed.ncbi.nlm.nih.gov/7959766

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Interchromosomal gene conversion as a possible mechanism for explaining divergence patterns of ZFY-related genes

Autor: Takashi Miyata, Kei-ichi Kuma, Hidenori Hayashida

Publikováno v: Journal of Molecular Evolution. 35

The divergence pattern of mammalian ZFY-related genes from human (ZFY and ZFX) and mouse (Zfy-1 and Zfx) was reexamined on the basis of nucleotide substitutions at the synonymous codon-alternating positions. It is possible to explain the unusual dive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c60e2a5f55d1bdbbf54962049ef97b1
https://doi.org/10.1007/bf00183228

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Autor: Kumao Toyoshima, Yuji Ohtsuki, Takashi Oka, Hidenori Hayashida, Toshihiro Nakanishi, Hajime Yoshizumi, Akira Hakura, Yoshiaki Murata

Publikováno v: Molecular Biology and Evolution.

Many proteins containing domains of a cysteine-rich repeated motif, such as epidermal growth factor (EGF), have been reported. Here we report strong similarity between the amino acid sequence of a plant toxin--i.e., purothionin and its homologues--an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3986c6352a52eda09a36464f2e19f89
https://doi.org/10.1093/oxfordjournals.molbev.a040754

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Recent gene conversion between genes encoding human red and green visual pigments

Autor: Hidenori Hayashida, Takashi Miyata, Kei-ich Kuma

Publikováno v: The Japanese Journal of Genetics. 63:367-371

Nucleotide sequences of the human X-linked red and green pigment genes were compared, and the number of silent substitutions per site (KSc) between these genes was analysed in comparison with the corresponding values of primate genes. Taking the reta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30bc55eabdb517c81e1c6249c15c4cb1
https://doi.org/10.1266/jjg.63.367

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