Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Hidenori Hase"'
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41238 (2012)
TNF can trigger two opposing responses: cell survival and cell death. TNFR1 activates caspases that orchestrate apoptosis but some cell types switch to a necrotic death when treated with caspase inhibitors. Several genes that are required to orchestr
Externí odkaz:
https://doaj.org/article/15fd6aff308a4de38eb4155dca09dd5f
Autor:
Hidemi Nakagawa, Ofelia Reyes Servin, Hidenori Hase, Yasuhiko Shinmura, Tsuyoshi Tsuchiya, Hideshi Torii, Mamitaro Ohtsuki, Toshimitsu Tokimoto, Akihiko Asahina
Publikováno v:
The Journal of Dermatology
The safety and efficacy of adalimumab were evaluated over 24 weeks in Japanese patients with psoriasis in routine clinical practice. In this multicenter, observational, open‐label, postmarketing study, primary efficacy measures included the Psorias
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe240e09ef5479d0bf714dd18c8b9334
https://doi.org/10.1111/1346-8138.13409
https://doi.org/10.1111/1346-8138.13409
Safety of Adalimumab and Predictors of Adverse Events in 1693 Japanese Patients with Crohn’s Disease
Autor:
Hidenori Hase, Tsuyoshi Tsuchiya, Haruhiko Ogata, Yasuhiko Shinmura, Mamoru Watanabe, Motohiro Okayasu, Toshiyuki Matsui, Toshifumi Hibi
Publikováno v:
Journal of Crohn's & Colitis
Background and Aims: Data from an all-cases post-marketing study were used to evaluate the safety and effectiveness of adalimumab in Japanese patients with Crohn’s disease [CD]. Methods: Patients received adalimumab for 24 weeks. Data from all pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d12d6e03d0f70ff12a254f033d88e26
http://europepmc.org/articles/PMC5007524
http://europepmc.org/articles/PMC5007524
Publikováno v:
Journal of Receptors and Signal Transduction. 30:121-132
B-cell-activating factor of the TNF family (BAFF) is a critical factor for B-cell survival and maturation through non-canonical nuclear factor kappaB (NF-kappaB) pathway, a NF-kappaB inducing kinase (NIK)-dependent pathway for the processing of NF-ka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd24c83168295ae5880191d4809a827a
https://doi.org/10.3109/10799891003634509
https://doi.org/10.3109/10799891003634509
Autor:
Ayano Kobayashi, Yoshikazu Totsuka, Gregg L. Semenza, Michail V. Sitkovsky, Riichi Takahashi, Yumiko Kanno, Hidenori Hase, Daisuke Sakurai, Hidefumi Kojima, Tetsuji Kobata
Publikováno v:
The Journal of Immunology. 184:154-163
Hypoxia-inducible factor (HIF)-1α plays a central role in oxygen homeostasis and energy supply by glycolysis in many cell types. We previously reported that an HIF-1α gene deficiency caused abnormal B cell development and autoimmunity. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9863a8733f74498e61a34c152934e38
https://doi.org/10.4049/jimmunol.0800167
https://doi.org/10.4049/jimmunol.0800167
Publikováno v:
Cell death and differentiation
TNF receptor 1 (TNFR1) ligation can result in cell survival or cell death. What determines which of the two opposing responses is triggered is not fully understood. The current model suggests that it is the activation of the NF-kappaB pathway and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4166bc84478d2d1e0eacdb17c77d6f
https://doi.org/10.1038/cdd.2009.41
https://doi.org/10.1038/cdd.2009.41
Autor:
Ryo Kurita, Hiroyuki Inoue, Yukoh Nakazaki, Yoshihito Beppu, Kenzaburo Tani, Xin K. Meng, Yusuke Nakamura, Gaku Sakaguchi, Hidenori Hase, Shigetaka Asano
Publikováno v:
Molecular Therapy. 14:599-606
Previously we demonstrated that gene transduction of the granulocyte-macrophage colony stimulating-factor (GM-CSF) gene into mouse tumor cells eliminated tumorigenicity in vivo. The rejection process of the subcutaneous tumor was as follows: transien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e665fb45e7845dada491b84e82c82bc
https://doi.org/10.1016/j.ymthe.2006.04.014
https://doi.org/10.1016/j.ymthe.2006.04.014
Autor:
Etsuko Abe, Terry F. Davies, Leslie S. Eldeiry, Lanying Liu, Hitoshi Amano, Takao Ando, Li Sun, Mone Zaidi, Hidenori Hase, Alina Brebene, Yuanzhen Peng
Publikováno v:
Proceedings of the National Academy of Sciences. 103:12849-12854
We have shown recently that by acting on the thyroid-stimulating hormone (TSH) receptor (TSHR), TSH negatively regulates osteoclast differentiation. Both heterozygotic and homozygotic TSHR null mice are osteopenic with evidence of enhanced osteoclast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bef4bbaec8397dcffd10e3ce8838bb1e
https://doi.org/10.1073/pnas.0600427103
https://doi.org/10.1073/pnas.0600427103
Autor:
Masafumi Abe, Nobuhiro Tsukada, Sachiko Yoshida, Jun Takizawa, Sadao Aoki, Shigeo Nakamura, Naoya Nakamura, Tetsuji Kobata, Masaru Kojima, Daisuke Sakurai, Hidenori Hase
Publikováno v:
Virchows Archiv. 447:53-60
BAFF-receptor (BAFF-R) is required for the successful maturation and survival of B-cells. We developed an anti-human BAFF-R monoclonal antibody (mAb), 8 A 7. The reactivity of 8 A 7 in normal and neoplastic tissue was examined by performing immunohis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa2815977f8f0217855fa843331c4a6
https://doi.org/10.1007/s00428-005-1275-6
https://doi.org/10.1007/s00428-005-1275-6
Autor:
Satoshi Takahashi, Reiko Kunisaki, Dale Ando, Noriharu Satoh, Kenzaburo Tani, Richard C. Mulligan, Junko Ohata, Hiroki Yoshikawa, K. Kawai, Miyuki Azuma, Shigetaka Asano, Yukoh Nakazaki, Taira Maekawa, Masazumi Eriguchi, Yusuke Inoue, Hideaki Tahara, Shinji Tomikawa, Yoshitsugu Yamada, Naoki Oyaizu, Arinobu Tojo, Kiyoshi Watari, Hideyuki Akaza, Yasushi Soda, Keisuke Takahashi, Maki Oiwa-Monna, Tadao Kakizoe, Masayuki Noguchi, Aikichi Iwamoto, Koh Okumura, Makoto Fujime, Hidenori Hase, Kisaburo Hanazawa, Yoshiaki Wakumoto, Utako Machida, Hirofumi Hamada, Naohide Yamashita, Shirley Clift
Publikováno v:
Molecular Therapy. 10(4):799-816
We produced lethally irradiated retrovirally GM-CSF-transduced autologous renal tumor cell vaccines (GVAX) from six Japanese patients with stage IV renal cell cancer (RCC). Four patients received GVAX ranging from 1.4 × 108 to 3.7 × 108 cells on 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014d06a5f6783814030040933edeb76e