Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hidenobu Tsutsui"'
Autor:
Takaomi Shimokawa, Hidenobu Tsutsui, Takeshi Miura, Masashi Takama, Kohei Hayashi, Toru Nishinaka, Tomoyuki Terada, Kozo Yoneda, Masayo Yamagata, Tokihito Yukimura
Publikováno v:
Journal of Pharmacological Sciences, Vol 139, Iss 3, Pp 137-142 (2019)
Ischemia/reperfusion injury is the most common cause of acute kidney injury. We previously revealed that pre-treatment with yohimbine or JP-1302 attenuated renal ischemia/reperfusion injury by inhibition of α2C-adrenoceptor antagonist. The aim of th
Externí odkaz:
https://doaj.org/article/128eb550d8d84b08829cfa8308a52125
Autor:
Natsuko Shigematsu, Mamoru Ohkita, Yasuo Matsumura, Haruna Hayashi, Hidenobu Tsutsui, Ryosuke Tanaka, Kohei Ito
Publikováno v:
Biological and Pharmaceutical Bulletin. 42:1883-1890
Since grape extract (GE) contains oligomeric proanthocyanidins and numerous polyphenols, dietary GE supplements may exert protective effects against various diseases. The present study investigated the pharmacological effects of GE derived from Chard
Autor:
Tomoyuki Terada, Tokihito Yukimura, Toru Nishinaka, Masayo Yamagata, Kohei Hayashi, Hidenobu Tsutsui, Kozo Yoneda, Masashi Takama, Takeshi Miura, Takaomi Shimokawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 139, Iss 3, Pp 137-142 (2019)
Ischemia/reperfusion injury is the most common cause of acute kidney injury. We previously revealed that pre-treatment with yohimbine or JP-1302 attenuated renal ischemia/reperfusion injury by inhibition of α2C-adrenoceptor antagonist. The aim of th
Autor:
Masayo Yamagata, Masashi Takama, Takeshi Miura, Hidenobu Tsutsui, Takaomi Shimokawa, Tomoyuki Terada, Tokihito Yukimura, Toru Nishinaka
Publikováno v:
European Journal of Pharmacology. 838:113-119
Nephrotoxicity is a major adverse reaction of the anticancer drug, cisplatin. We investigated the renoprotective effects of the α2-adrenoceptor antagonist, yohimbine and selective α2C-adrenoceptor antagonist, JP-1302, in cisplatin-treated Sprague D
Autor:
Takeshi Miura, Hidenobu Tsutsui, Takao Tanba, Masayo Yamagata, Shuhei Yoshida, Tomoyuki Terada, Tokihito Yukimura, Takaomi Shimokawa, Ayumi Tojo, Masashi Takama, Toru Nishinaka
Publikováno v:
European Journal of Pharmacology. 781:36-44
Excitation of renal sympathetic nervous activity and the resulting increased levels of renal venous norepinephrine play important roles in renal ischaemia/reperfusion injury in rats. This study examined the effects of yohimbine, a non-selective α2-a
Autor:
Toru Nishinaka, Tokihito Yukimura, Takaomi Shimokawa, Hidenobu Tsutsui, Tomoyuki Terada, Takeshi Miura, Masayo Yamagata, Masashi Takama
Publikováno v:
European journal of pharmacology. 818
Increases in renal sympathetic nerve activity during ischaemia and renal venous norepinephrine levels after reperfusion play important roles in the development of ischaemia/reperfusion-induced acute kidney injury. In the present study, we examined th
Autor:
Yasuo Matsumura, Tokihito Yukimura, Hidenobu Tsutsui, Takahiro Sugiura, Masanori Takaoka, Mamoru Ohkita, Kentaro Hayashi
Publikováno v:
European Journal of Pharmacology. 718:173-180
Enhancement of renal sympathetic nerve activity during renal ischemia and norepinephrine overflow from the kidney after reperfusion play important roles in the development of ischemic acute kidney injury. Recently, we have found that moxonidine, an
Autor:
Tokihito Yukimura, Yuri Morikawa, Hidenobu Tsutsui, Yasuo Matsumura, Mamoru Ohkita, Ryosuke Tanaka, Maki Yazawa
Publikováno v:
Clinical and experimental pharmacologyphysiology. 44(3)
Ischaemic acute kidney injury (AKI) is a leading killer of both sexes; however, resistance to this injury is higher among women than men. We found that renal venous noradrenaline (NAd) overflow after reperfusion played important roles in the developm
Autor:
Shuhei Kobuchi, Masanori Takaoka, Yasuo Matsumura, Masayo Yamagata, Takahiro Sugiura, Hidenobu Tsutsui, Ryosuke Tanaka, Tokihito Yukimura, Mamoru Ohkita
Publikováno v:
European Journal of Pharmacology. 683:270-275
Enhanced renal sympathetic nerve activity during an ischemic period and renal venous norepinephrine overflow after reperfusion play important roles in the development of ischemic acute kidney injury. In this study, we examined the effect of 17β-estr
Autor:
Rie Suzuki, Kazuhide Ayajiki, Yasuo Matsumura, Takahiro Sugiura, Shuhei Kobuchi, Hidenobu Tsutsui, Ryosuke Tanaka, Takuya Shintani, Toshihide Fujii, Mamoru Ohkita
Publikováno v:
European Journal of Pharmacology. 623:113-118
Enhanced renal sympathetic nerve activity during ischemic period and the renal venous norepinephrine overflow after reperfusion play important roles in the development of ischemic acute kidney injury. We investigated the effect of gamma-aminobutyric