Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hidemi Nonaka"'
Autor:
Yoshiyuki Rikitake, Hidemi Nonaka, Yaz Y. Kisanuki, Kazuhiko Nakayama, Suko Adiarto, Ken-ichi Hirata, Dyah Wulan Anggrahini, Noriaki Emoto, Naoko Iwasa, Bambang Widyantoro, Masashi Yanagisawa
Publikováno v:
Cardiovascular Research. 82:143-151
Aims Although endothelin-1 (ET-1) has been suggested to contribute to the pathogenesis of neointima formation and atherosclerosis, the individual roles of ET-1 derived from certain cell types in this disease remain unclear. In this study, we determin
Autor:
Yoshiro Naito, Mitsumasa Ohyanagi, Takeshi Tsujino, Hidemi Nonaka, Mika Matsumoto, Tsuyoshi Sakoda, Tohru Masuyama
Publikováno v:
Clinical and Experimental Hypertension. 31:271-280
We examined the effect of high salt intake on mean arterial pressure and circadian blood pressure rhythm in Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model of type II diabetes mellitus. Mean arterial pressure, fasting blood glucose, and fasti
Autor:
Mitsuhiro Yokoyama, Noriaki Emoto, Kazuhiro Yagita, Hidemi Nonaka, Hitoshi Okamura, Hiroyuki Fukuya
Publikováno v:
Biochemical and Biophysical Research Communications. 354:924-928
In mammals, behavioral and physiological processes display 24-h rhythms that are regulated by a circadian system. In the present study, we investigated the possibility that the expression of clock genes in peripheral leukocytes can be used to assess
Autor:
Mohammad Saifur Rohman, Hidemi Nonaka, Kazuhiro Yagita, Gijsbertus T. J. van der Horst, Masataka Nishimura, Hitoshi Okamura, Noriaki Emoto, Ryusuke Okura, Mitsuhiro Yokoyama, Masafumi Matsuo
Publikováno v:
ResearcherID
Kidney International, 67(4), 1410-1419. Elsevier Inc.
Kidney International, 67(4), 1410-1419. Elsevier Inc.
Circadian clock genes directly regulate expression of the Na + /H + exchanger NHE3 in the kidney. Background Daily rhythms in mammalian physiology are generated by a transcription/translation feedback loop orchestrated by a set of clock genes. Howeve
Autor:
Hidemi Nonaka, Masakuni Suematsu, Yoshimichi Inoue, Ryuji Toh, Yasuo Kitagawa, Noriaki Emoto, Ken-ichi Hirata, Tatsuro Ishida, Kunihiro Nishimura, Takashi Miki
Publikováno v:
Hypertension research : official journal of the Japanese Society of Hypertension. 35(11)
The objective of this study is to examine the effects of thiazide diuretics, plus medium-dose losartan versus maximal-dose angiotensin II receptor blockers (ARBs) on blood pressure (BP) in Japanese patients with uncontrolled hypertension despite the
Autor:
Dyah Wulan Anggrahini, Noriaki Emoto, Kazuhiko Nakayama, Bambang Widyantoro, Kazuya Miyagawa, Hidemi Nonaka, Vita Yanti Anggraeni, Yaz Y. Kisanuki, Masashi Yanagisawa, Kenichi Hirata
Publikováno v:
Circulation. 118
Endothelium plays important role in protective mechanism of vascular wall. The balance between endothelin-1 (ET-1) and nitric oxide provide endothelial barrier to lipoprotein retain and macrophage recruitment. In contrasts, ET-1 is also a strong vaso
Autor:
Kazuya Miyagawa, Naoko Iwasa, Suko Adiarto, Masashi Yanagisawa, Yaz Y. Kisanuki, Noriaki Emoto, Kazuhiko Nakayama, Dyah Wulan Anggrahini, Hidemi Nonaka, Bambang Widyantoro
Publikováno v:
Circulation. 116
Complex mechanism of the chronic inflammatory process in vascular injury and atherosclerosis involves various types of cells and cytokines. Previous in vitro studies suggest that Endothelin-1 (ET-1) is produced by those cells, induces expression of s
Autor:
Bambang Widyantoro, Suko Adiarto, Naoko Iwasa, Kazuhiko Nakayama, Dyah W Anggrahini, Kazuya Miyagawa, Hidemi Nonaka, Takashi Suzuki, Yaz Y Kisanuki, Masashi Yanagisawa, Noriaki Emoto
Publikováno v:
Circulation. 116
High plasma endothelin-1 (ET-1) level has been associated with diabetic cardiovascular and renal complications, which remained prevalent despite good glycemic control. Since endothelial dysfunction, which is characterized by enhanced ET-1 secretion,
Alterations of circadian expressions of clock genes in Dahl salt-sensitive rats fed a high-salt diet
Autor:
Takao Mohri, Kazuhiro Yagita, Noriaki Emoto, Hiroyuki Fukuya, Hidemi Nonaka, Hitoshi Okamura, Mitsuhiro Yokoyama
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 42(2)
In mammals, behavioral and physiologic processes display 24-hour rhythms that are regulated by a circadian system consisting of central and peripheral oscillators. Because various cardiovascular functions show diurnal variations and abnormal patterns
Autor:
Hidemi Nonaka, Takeshi Tsujino, Hisashi Harada, Noriaki Emoto, Yasuhiro Watari, Mitsuhiro Yokoyama
Publikováno v:
Heart and vessels. 19(3)
Taurine is known to have antihypertensive and lipid-lowering effects in some experimental models and patients. On the other hand, intracellular free calcium and magnesium play important roles in regulating the tonus of blood vessels and insulin sensi