Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Hideko Onodera"'
Publikováno v:
Drug Metabolism and Pharmacokinetics. 15:439-451
Capecitabine, a new orally available fluorpyrimidine carbamate, is converted to 5-fluorouracil (5-FU) by three sequential reactions involving the enzymes carboxylesterase, cytidine (Cyd) deaminase, and pyrimidine nucleoside phosphorylase (PyNPase). I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::508f2ac59fe725dc554958d2f0458c88
https://doi.org/10.2133/dmpk.15.439
https://doi.org/10.2133/dmpk.15.439
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 11:379-384
A relatively simple and sensitive high-performance liquid chromatographic (HPLC) method is described for measuring galocitabine (Ro 09-1390) and its meatbolites, i.e. 5'-deoxy-fluorocytidine (5'-DFCR), 5'-deoxy-fluorouridine (5'-DFUR) and 5-fluoroura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059915e472d4c4a4aba3a733d4d41bd5
https://doi.org/10.1016/0731-7085(93)80032-v
https://doi.org/10.1016/0731-7085(93)80032-v
Autor:
Isami Kuruma, Tomoo Funaki, Hideo Fukazawa, Naomi Ushiyama, Hideko Onodera, Yuko Tsukamoto, Chieko Tagami
Publikováno v:
The Journal of pharmacy and pharmacology. 46(7)
Catechol-O-methyltransferase (COMT) catalyses the transfer of the methyl group from S-adenyl-l-methionine (SAM) to one of the hydroxy groups of a catechol, usually the hydroxy group in position 3. COMT is present mainly in a soluble form (S-COMT) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a46291349f93ac6501907421b510f1c
https://pubmed.ncbi.nlm.nih.gov/7996385
https://pubmed.ncbi.nlm.nih.gov/7996385