Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hideki Terajima"'
Publikováno v:
PLoS Biology, Vol 19, Iss 7, p e3001292 (2021)
Among over 150 distinct RNA modifications, N6-methyladenosine (m6A) and adenosine-to-inosine (A-to-I) RNA editing represent 2 of the most studied modifications on mammalian mRNAs. Although both modifications occur on adenosine residues, knowledge on
Externí odkaz:
https://doaj.org/article/6b70eecb7a0b450fa7b86a323b5aaee8
Autor:
Takashi Ogino, Naoya Matsunaga, Takahiro Tanaka, Tomohito Tanihara, Hideki Terajima, Hikari Yoshitane, Yoshitaka Fukada, Akito Tsuruta, Satoru Koyanagi, Shigehiro Ohdo
Publikováno v:
eLife, Vol 10 (2021)
Disruption of the circadian clock machinery in cancer cells is implicated in tumor malignancy. Studies on cancer therapy reveal the presence of heterogeneous cells, including breast cancer stem-like cells (BCSCs), in breast tumors. BCSCs are often ch
Externí odkaz:
https://doaj.org/article/c73d43d82c3a44c2829ec54f75f53fd7
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Abstract In mammals, the central circadian clock is located in the suprachiasmatic nucleus (SCN) of the hypothalamus and it orchestrates peripheral clocks in the whole body to organize physiological and behavioral rhythms. Light-induced phase-shift o
Externí odkaz:
https://doaj.org/article/2306fa7987464a5eb119a4d7b722dfab
Publikováno v:
PLoS Biology, Vol 19, Iss 7, p e3001292 (2021)
PLoS Biology
PLoS Biology
Among over 150 distinct RNA modifications, N6-methyladenosine (m6A) and adenosine-to-inosine (A-to-I) RNA editing represent 2 of the most studied modifications on mammalian mRNAs. Although both modifications occur on adenosine residues, knowledge on
Autor:
Satoru Koyanagi, Naoya Matsunaga, Akito Tsuruta, Hideki Terajima, Yoshitaka Fukada, Hikari Yoshitane, Tomohito Tanihara, Takahiro Tanaka, Shigehiro Ohdo, Takashi Ogino
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Disruption of the circadian clock machinery in cancer cells is implicated in tumor malignancy. Studies on cancer therapy reveal the presence of heterogeneous cells, including breast cancer stem-like cells (BCSCs), in breast tumors. BCSCs are often ch
Autor:
Shun Liu, Allen C. Zhu, Chuan He, Hui-Lung Sun, Yu-Ying He, Mien Chie Hung, Bryan T. Harada, Hideki Terajima, Yawei Gao, Zijie Zhang, Linda Zhang, Qili Fei, Marc Bissonnette
Publikováno v:
Mol Cell
N(6)-methyladenosine (m(6)A) is the most abundant mRNA modification, which is installed by the METTL3-METTL14-WTAP methyltransferase complex. Although the importance of m(6)A methylation in mRNA dynamics has been well-documented recently, the regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a87a0f9c86723cb5c0a3910b3eb9fd
https://europepmc.org/articles/PMC7720844/
https://europepmc.org/articles/PMC7720844/
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Scientific Reports
Scientific Reports
In mammals, the central circadian clock is located in the suprachiasmatic nucleus (SCN) of the hypothalamus and it orchestrates peripheral clocks in the whole body to organize physiological and behavioral rhythms. Light-induced phase-shift of the SCN
Autor:
Hideki Terajima, Yutaka Suzuki, Yoshitaka Fukada, Haruka Ozaki, Shigeki Shimba, Shinya Kuroda, Hikari Yoshitane, Wataru Iwasaki
Publikováno v:
Nature Genetics. 49:146-151
It has been proposed that the CLOCK-ARNTL (BMAL1) complex drives circadian transcription of thousands of genes, including Per and Cry family genes that encode suppressors of CLOCK-ARNTL-dependent transcription. However, recent studies demonstrated th
Autor:
Junichiro Yajima, Masataka Kinjo, Shigeko Kawai-Noma, Toshikazu Tsuji, Hideki Taguchi, Chan-Gi Pack, Hideki Terajima, Takayuki Nishizaka
Publikováno v:
Biochemical and Biophysical Research Communications. 405(No. 4):638-643
Yeast is a model eukaryote with a variety of biological resources. Here we developed a method to track a quantum dot (QD)-conjugated protein in the budding yeast Saccharomyces cerevisiae. We chemically conjugated QDs with the yeast prion Sup35, incor
Autor:
Shigeki Shimba, Yutaka Suzuki, Wataru Iwasaki, Naoki Kosaka, Hideki Terajima, Yoshitaka Fukada, Haruka Ozaki, Hikari Yoshitane, Ngoc-Hien Du, Taihei Fujimori, Toshihisa Takagi, Sumio Sugano
Publikováno v:
Molecular and cellular biology. 34(10)
In mammalian circadian clockwork, the CLOCK-BMAL1 complex binds to DNA enhancers of target genes and drives circadian oscillation of transcription. Here we identified 7,978 CLOCK-binding sites in mouse liver by chromatin immunoprecipitation-sequencin