Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hideki Narumi"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Microbial flora is investigated to be related with neuropathological conditions in Alzheimer’s disease (AD), and is attracting attention as a drug discovery resource. However, the relevance between the soil microbiota and the pathological
Externí odkaz:
https://doaj.org/article/4d2a5669fcf046e58186e518efd579e7
Autor:
Hiroshi Yokokawa, Midori Shinohara, Yuji Teraoka, Michio Imamura, Noriko Nakamura, Noriyuki Watanabe, Tomoko Date, Hideki Aizaki, Tomokatsu Iwamura, Hideki Narumi, Kazuaki Chayama, Takaji Wakita
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274283 (2022)
In recent years, new direct-acting antivirals for hepatitis C virus (HCV) have been approved, but hepatitis C continues to pose a threat to human health. It is important to develop neutralizing anti-HCV antibodies to prevent medical and accidental in
Externí odkaz:
https://doaj.org/article/eb687d3a76cf48d9a935c8025f9c022f
Autor:
Hyongi, Chon, Satoshi, Kanamori, Kazuhiro, Hibino, Takashi, Nagahara, Tomohiko, Suzuki, Keiichiro, Ohara, Hideki, Narumi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 80:129117
The conserved N-linked glycan at the Fc domain of recombinant monoclonal antibodies is an attractive target for site-specific payload conjugation for preparation of homogenous antibody-drug conjugates (ADCs). Here, we report a novel ADC constructing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a15c4d9156586ba38fa1204efbe592e
https://doi.org/10.1016/j.bmcl.2022.129117
https://doi.org/10.1016/j.bmcl.2022.129117
Autor:
Naoki Izumimoto, Mitsuhiro Konno, Masaki Moriyama, Natsumi Yuzawa, Tomokatsu Iwamura, Hideki Narumi
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:4-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bea9b286d2659669479e3682152f4004
https://doi.org/10.1254/jpssuppl.96.0_4-b-p-269
https://doi.org/10.1254/jpssuppl.96.0_4-b-p-269
Autor:
Hideki Narumi, Katsuyuki Mori, Masashi Uchida, Tomohiko Suzuki, Tadatsugu Taniguchi, Yoshiaki Tsushima, Hiromi Tsuchiyama, Tomokatsu Iwamura, Kazumi Nishimura, Kiyoshi Okano, Shinobu Momen, Asano Tomomi, Yamashita Yuji, Akiko Izawa, Koji Yamashita, Hideyuki Yanai
Publikováno v:
Cancer Science
Malignant ascites manifests as an end-stage event during the progression of a number of cancers and lacks a generally accepted standard therapy. Interferon-β (IFN-β) has been used to treat several cancer indications; however, little is known about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d78dfd6b9667bb497f6ecafcf367c2bf
http://europepmc.org/articles/PMC5406538
http://europepmc.org/articles/PMC5406538
Autor:
Mie Kainoh, Hiromi Kan, Kazuaki Chayama, Hideki Narumi, Takuro Uchida, Daiki Miki, Nobuhiko Hiraga, Michio Imamura, Hidenori Ochi, Rieko Shimozono, Tomokatsu Iwamura, Tomohiko Suzuki, Masataka Tsuge, Hiromi Abe-Chayama, Grace Naswa Makokha, C. Nelson Hayes, Tadatsugu Taniguchi
Publikováno v:
Antimicrobial agents and chemotherapy. 61(6)
Although nucleot(s)ide analogues and pegylated interferon alpha 2a (PEG-IFN-α2a) can suppress hepatitis B virus (HBV) replication, it is difficult to achieve complete HBV elimination from hepatocytes. A novel site-specific pegylated recombinant huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b36b7b45f5ed6b331af90d0cfde1dab1
https://pubmed.ncbi.nlm.nih.gov/28373196
https://pubmed.ncbi.nlm.nih.gov/28373196
Publikováno v:
Hepatology Research. 37:121-126
We studied the effect of combination therapy consisting of IFN-β and ribavirin on mouse hepatitis virus (MHV) infection in mice. It was found that the combination of IFN-α and ribavirin was more effective in increasing survival time than IFN-α tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b370d16cba6ccb9d63ff3dcb921cf550
https://doi.org/10.1111/j.1872-034x.2007.00017.x
https://doi.org/10.1111/j.1872-034x.2007.00017.x
Autor:
Eishun Tsuchida, Yosuke Okamura, Hideki Narumi, Shinji Takeoka, Hiromi Tsuchiyama, Yasuo Ikeda, Mie Kainoh, Yuji Teramura, Makoto Handa
Publikováno v:
Biochemical and Biophysical Research Communications. 306:256-260
The recombinant fragment of the platelet membrane glycoprotein Ia/IIa (rGPIa/IIa) was conjugated to the polymerized albumin particles (polyAlb) with the average diameter of 180 nm. The intravenous administration of rGPIa/IIa-polyAlb to thrombocytopen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9052a30ae685cf0f4a46a6151a026b8e
https://doi.org/10.1016/s0006-291x(03)00943-4
https://doi.org/10.1016/s0006-291x(03)00943-4
Publikováno v:
European Journal of Biochemistry. 214:181-187
The cDNA of silkworm (Bombyx mori) antichymotrypsin (sw-Achy) was cloned from larval fat body and its nucleotide sequence was determined. The deduced amino acid sequence of mature sw-Achy begins with Phe1 and ends with Phe384, with a preceding 16-ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae0816dc7f602de30c961883b6f4f7f5
https://doi.org/10.1111/j.1432-1033.1993.tb17911.x
https://doi.org/10.1111/j.1432-1033.1993.tb17911.x
Publikováno v:
International immunopharmacology. 10(9)
Administration of oligomannose-coated liposomes (OMLs) in mice can induce Th1 immune responses against antigens entrapped in the OMLs. In the present study, we investigated the anti-allergic effect of treatment with oligomannose-coated liposomes (OML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce007f51212326467f7a29548b10612a
https://pubmed.ncbi.nlm.nih.gov/20584630
https://pubmed.ncbi.nlm.nih.gov/20584630