Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hideki Mochida"'
Autor:
Satomi Nishikawa, Hironobu NiISHINA, Yasushi Horai, Hideki Mochida, Yuko Ono, Mao Mizukawa, Airi Akatsuka, Kana Takemoto
Publikováno v:
Translational and Regulatory Sciences. 2:72-79
Autor:
Masato Takeuchi, Keisuke Fujitaka, Hideki Mochida, Taku Murakami, Tetsuhiro Kakimoto, Kenji Arakawa
Publikováno v:
Biomedical Reports
Urinary nano-extracellular vesicles (NVs), including exosomes and microvesicles, are considered potential biomarkers for kidney diseases using liquid biopsies. However, clinical application of urinary NVs has not yet been validated. In the present st
mRNAs in urinary nano‑extracellular vesicles as potential biomarkers for non‑invasive kidney biopsy.
Autor:
KEISUKE FUJITAKA, TAKU MURAKAMI, MASATO TAKEUCHI, TETSUHIRO KAKIMOTO, HIDEKI MOCHIDA, KENJI ARAKAWA
Publikováno v:
Biomedical Reports; Jan2021, Vol. 14 Issue 1, p1-8, 8p
Publikováno v:
The Proceedings of The Manufacturing & Machine Tool Conference. :C06
Autor:
Yosuke Inui, Akiyoshi Fukamizu, Fumiko Yamairi, Hideki Mochida, Kenji Arakawa, Junji Ishida, Miyoko Okada
Publikováno v:
Biomedical Reports. 1:359-364
Renal dysfunction is accelerated by various factors such as hypertension, aging and diabetes. Glomerular hyper-filtration, considered one of the major risk factors leading to diabetic nephropathy, is often encountered in diabetic patients. However, t
Autor:
Takashi Sasaki, Yasuhiro Yamada, Jun Kotera, Hirotaka Inoue, Hideki Mochida, Kohei Kikkawa, Shiyin Yee, Kotomi Fujishige, Tsunehisa Noto, Kenji Omori, Koki Kojima, Tamaki Kobayashi
Publikováno v:
Journal of Urology. 188:668-674
We investigated the in vitro inhibitory effects of avanafil, a novel, potent inhibitor of phosphodiesterase-5, on 11 phosphodiesterases. We also studied its potentiation of penile tumescence in dogs.Phosphodiesterase assay was done with the 4 phospho
Autor:
Toshiaki Sakamoto, Kohei Kikkawa, Jun Kotera, Koichiro Yamada, Kotomi Fujishige, Yuichi Koga, Kenji Omori, Kenji Matsuki, Hiroshi Morimoto, Hideki Mochida, Masataka Hikota
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(7)
A novel series of highly selective phosphodiesterase 5 (PDE5) inhibitors was found. 8H-Pyrido[2,3-d]pyrimidin-7-one derivatives bearing an (S)-2-(hydroxymethyl)pyrrolidin-1-yl group at the 2-position and a 3-chloro-4-methoxybenzyl group at the 8-posi
Publikováno v:
European Journal of Pharmacology. 485:283-288
T-0156 (2-(2-methylpyridin-4-yl)methyl-4-(3,4,5-trimethoxyphenyl)-8-(pyrimidin-2-yl)methoxy-1,2-dihydro-1-oxo-2,7-naphthyridine-3-carboxylic acid methyl ester hydrochloride) is a newly synthesized phosphodiesterase type 5 inhibitor, and its potency a
Publikováno v:
European Journal of Pharmacology. 440:45-52
The vasorelaxant effects of sildenafil and T-1032 [methyl-2-(4-aminophenyl)-1,2-dihydro-1-oxo-7-(2-pyridinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-3-isoquinoline carboxylate sulfate], two phosphodiesterase type 5 inhibitors, were examined in the isolate
Publikováno v:
European Journal of Pharmacology. 425:51-55
We studied the role of adenosine and P2 receptors in the pelvic nerve stimulation-induced penile tumescence in anesthetized dogs. A local intracavernous injection of adenosine induced the tumescence, which was abolished by intracavernous 8-(p-sulfoph