Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Hideki Jona"'
Autor:
Hiroshi Kawamoto, Yoshikazu Iwasawa, Jun Shibata, Yasuhiro Goto, Shigeru Nakajima, Sachie Arai, Masanori Asai, Osamu Okamoto, Hideki Jona
Publikováno v:
Tetrahedron: Asymmetry. 20:2439-2446
An efficient and practical asymmetric synthesis of 1- tert -butyl 3-methyl (3 R ,4 R )-4-(2-oxo-2,3-dihydro-1 H -benzimidazol-1-yl)piperidine-1,3-dicarboxylate 1 , a useful intermediate for the synthesis of nociceptin antagonists, has been developed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d659377a0a65ed0677cf543fef713b3a
https://doi.org/10.1016/j.tetasy.2009.07.046
https://doi.org/10.1016/j.tetasy.2009.07.046
Publikováno v:
Bulletin of the Chemical Society of Japan. 76:1829-1848
A convergent total synthesis of F1α antigen, a member of the tumor-associated O-linked mucin glycosyl amino acid, was tried by one-pot sequential glycosylation. Highly α-selective glycosylation of amino acid 7 with thioglycoside 6 was successfully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e955c6d3ae33b62e530ee520d628676
https://doi.org/10.1246/bcsj.76.1829
https://doi.org/10.1246/bcsj.76.1829
Autor:
Zhiguo J. Song, Yoshimi Tsuchiya, Shigemitsu Okada, Takayuki Nemoto, Matthew M. Zhao, Atsushi Akao, Yoshiaki Kato, Koji Tomimoto, Kenji Niiyama, Hideki Jona, Toshiaki Mase
Publikováno v:
Tetrahedron. 58:3409-3415
An asymmetric synthesis of a selective endothelin A receptor antagonist 1b is described. A highly substituted pyridine intermediate 11a was efficiently prepared via a mono-amination of inexpensive 2,6-dichloropyridine followed by a Vilsmeier formylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d31d3a961ac6557655fed8240b8286b
https://doi.org/10.1016/s0040-4020(02)00280-6
https://doi.org/10.1016/s0040-4020(02)00280-6
Publikováno v:
Bulletin of the Chemical Society of Japan. 75:291-309
A catalytic and stereoselective glycosylation of various glycosyl acceptors, such as methyl glycosides, thioglycosides, or a disarmed glycosyl fluoride, with benzyl-protected armed glycosyl fluoride was successfully carried out by using various proti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eaa921975a12c92c752a672a9f112fd
https://doi.org/10.1246/bcsj.75.291
https://doi.org/10.1246/bcsj.75.291
Autor:
Teruaki MUKAIYAMA, Hideki JONA
Publikováno v:
Proceedings of the Japan Academy, Series B. 78:73-83
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6c70e0a971d38bde04e4617ab144582
https://doi.org/10.2183/pjab.78.73
https://doi.org/10.2183/pjab.78.73
Autor:
Shouichi Hiraga, Atsushi Akao, Shigemitsu Okada, Koji Tomimoto, Yoshimi Tsuchiya, Toshiaki Mase, Hideki Jona, Kenji Niiyama, Yoshiaki Kato
Publikováno v:
Chemical and Pharmaceutical Bulletin. 50:1066-1072
An asymmetric synthesis of a selective endothelin A receptor antagonist 1b is described. Asymmetric conjugate addition of aryllithium derived from 18 to the chiral oxazoline 17 followed by hydrolysis afforded 15 in 96% ee via purification as (S)-(-)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef5aa38c12516e8d35ed44768f26cbb
https://doi.org/10.1248/cpb.50.1066
https://doi.org/10.1248/cpb.50.1066
Autor:
Hiroki Sato, Hideo Kiyonaga, Minoru Moriya, Yuichi Sugimoto, Shinnosuke Abe, Chinatsu Ikeura, Aya Shimizu, Terutaka Hashizume, Hideki Jona, Rie Nagano, Hideaki Imamura, Hajime Morishima, Norikazu Ohtake, Koji Yamada, Masato Nakano
Publikováno v:
Bioorganic & Medicinal Chemistry. 9:1571-1578
A new class of 1 beta-methylcarbapenems bearing a doubly quaternarized 1,4-diazabicyclooctane (DABCO) substituted dithiocarbamate moiety at the C-2 side chain was prepared, and the biological profiles of the compounds, including in vitro and in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c872a2be3182e91c4bc9d9c021e0608
https://doi.org/10.1016/s0968-0896(01)00044-x
https://doi.org/10.1016/s0968-0896(01)00044-x
Publikováno v:
Helvetica Chimica Acta. 83:1901-1918
A catalytic and stereoselective glycosylation of several glycosyl acceptors with β-D-glycosyl fluoride was successfully performed in the presence of a catalytic amount of trityl tetrakis(pentafluorophenyl)borate (TrB(C6F5)4) or trifluoromethanesulfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8318abe800a4721cae81ccc94c8e17c1
https://doi.org/10.1002/1522-2675(20000809)83:8<1901::aid-hlca1901>3.0.co
https://doi.org/10.1002/1522-2675(20000809)83:8<1901::aid-hlca1901>3.0.co
Autor:
Koji Yamada, Aya Shimizu, Norikazu Ohtake, Hideaki Imamura, Hajime Morishima, Terutaka Hashizume, Ryosuke Ushijima, Rie Nagano, Hideki Jona, Hiroki Sato
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 10:109-113
1Beta-methylcarbapenems having various 3,5-disubstituted pyrrolidinylthio-side chains at C-2 were designed and synthesized. Evaluation of their antibacterial activities indicated that J-111,347 (1a) is the first example of an extremely broad spectrum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a277ff2888880865174a76457ed9b4d
https://doi.org/10.1016/s0960-894x(99)00657-5
https://doi.org/10.1016/s0960-894x(99)00657-5
Autor:
Aya Shimizu, Hideki Jona, Minoru Moriya, Hiroki Sato, Hideaki Imamura, Hideo Kiyonaga, Norikazu Ohtake, Masato Nakano, Ryosuke Ushijima, Nakagawa Susumu
Publikováno v:
Bioorganic & Medicinal Chemistry. 6:1089-1101
A new series of 1β-methyl carbapenems, in which a disubstituted-aminothiocarbonylthio moiety was attached to the C-2 position of the carbapenem nucleus, were prepared and evaluated for anti-MRSA activity. These derivatives showed good in vitro antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82629913e69914e8a2e94d8b5c106b72
https://doi.org/10.1016/s0968-0896(98)00069-8
https://doi.org/10.1016/s0968-0896(98)00069-8