Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Hideki Innan"'
Autor:
Yu Sugihara, Lester Young, Hiroki Yaegashi, Satoshi Natsume, Daniel J. Shea, Hiroki Takagi, Helen Booker, Hideki Innan, Ryohei Terauchi, Akira Abe
Publikováno v:
PeerJ, Vol 10, p e13170 (2022)
Summary Bulked segregant analysis implemented in MutMap and QTL-seq is a powerful and efficient method to identify loci contributing to important phenotypic traits. However, the previous pipelines were not user-friendly to install and run. Here, we d
Externí odkaz:
https://doaj.org/article/75faf1497c5546acaaa7bd3b67af3dff
Publikováno v:
Ecology and Evolution, Vol 12, Iss 1, Pp n/a-n/a (2022)
Abstract For community ecologists, “neutral or not?” is a fundamental question, and thus, rejecting neutrality is an important first step before investigating the deterministic processes underlying community dynamics. Hubbell's neutral model is a
Externí odkaz:
https://doaj.org/article/85811474d8b04ca589b601e83245fcb1
Autor:
Takahiro Sakamoto, Hideki Innan
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 1 (2021)
AbstractThe turnover of sex-determining loci has repeatedly occurred in a number of species, rather than having a diverged pair of sex chromosomes. We model the turnover process by considering a linked locus under sexually antagonistic selection. The
Externí odkaz:
https://doaj.org/article/ad8135e0de1047a69d8a089252bb6888
Autor:
Shotaro Sakimura, Satoshi Nagayama, Mitsuko Fukunaga, Qingjiang Hu, Akihiro Kitagawa, Yuta Kobayashi, Takanori Hasegawa, Miwa Noda, Yuta Kouyama, Dai Shimizu, Tomoko Saito, Atsushi Niida, Yusuke Tsuruda, Hajime Otsu, Yoshihiro Matsumoto, Hiroki Uchida, Takaaki Masuda, Keishi Sugimachi, Shin Sasaki, Kazutaka Yamada, Kazuki Takahashi, Hideki Innan, Yutaka Suzuki, Hiromi Nakamura, Yasushi Totoki, Shinichi Mizuno, Masanobu Ohshima, Tatsuhiro Shibata, Koshi Mimori
Publikováno v:
PLoS Genetics, Vol 17, Iss 1, p e1009113 (2021)
A Darwinian evolutionary shift occurs early in the neutral evolution of advanced colorectal carcinoma (CRC), and copy number aberrations (CNA) are essential in the transition from adenoma to carcinoma. In light of this primary evolution, we investiga
Externí odkaz:
https://doaj.org/article/368965ee3f5c406883ce91f3142e4dd0
Publikováno v:
Genes, Vol 13, Iss 2, p 190 (2022)
In his influential book “Evolution by Gene Duplication”, Ohno postulated that frameshift mutation could lead to a new function after duplication, but frameshift mutation is generally thought to be deleterious, and thus drew little attention in fu
Externí odkaz:
https://doaj.org/article/e3dad29ad40140318fa6d7c0ccc7f33e
Autor:
Atsushi Niida, Takanori Hasegawa, Hideki Innan, Tatsuhiro Shibata, Koshi Mimori, Satoru Miyano
Publikováno v:
PeerJ, Vol 8, p e8842 (2020)
Because cancer evolution underlies the therapeutic difficulties of cancer, it is clinically important to understand the evolutionary dynamics of cancer. Thus far, a number of evolutionary processes have been proposed to be working in cancer evolution
Externí odkaz:
https://doaj.org/article/30d5b46511b64ce1b3005cf8e644bc3b
Autor:
Cian Glenfield, Hideki Innan
Publikováno v:
Genes, Vol 12, Iss 9, p 1376 (2021)
Chromosomal rearrangement and genome instability are common features of cancer cells in human. Consequently, gene duplication and gene fusion events are frequently observed in human malignancies and many of the products of these events are pathogenic
Externí odkaz:
https://doaj.org/article/ceb789a8ce47443ea0d48438ee8ce330
Autor:
Jeffrey A Fawcett, Fumio Sato, Takahiro Sakamoto, Watal M Iwasaki, Teruaki Tozaki, Hideki Innan
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0218407 (2019)
The domestication process of plants and animals typically involves intense inbreeding and directional selection for various traits. Here, we genotyped 370 Japanese Thoroughbred horses using the recently developed 670k SNP array and performed various
Externí odkaz:
https://doaj.org/article/41da38480a074175b3423e55346bc168
Autor:
Watal M Iwasaki, Hideki Innan
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184229 (2017)
As cancer cell populations evolve, they accumulate a number of somatic mutations, resulting in heterogeneous subclones in the final tumor. Understanding the mechanisms that produce intratumor heterogeneity is important for selecting the best treatmen
Externí odkaz:
https://doaj.org/article/cb22c3b81d4e47a29b999854ab41192c
Publikováno v:
Genes, Vol 2, Iss 2, Pp 313-331 (2011)
Interlocus gene conversion occurs such that a certain length of DNA fragment is non-reciprocally transferred (copied and pasted) between paralogous regions. To understand the rate and tract length of gene conversion, there are two major approaches. O
Externí odkaz:
https://doaj.org/article/e885fdae88164c24a62f955037b31c52