Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Hideki Enomoto"'
Autor:
Yuta Yoshioka, Yoshihisa Tachibana, Toshihiro Uesaka, Hiroyuki Hioki, Yuya Sato, Takumi Fukumoto, Hideki Enomoto
Publikováno v:
Biochemical and Biophysical Research Communications. 608:66-72
Enteroendocrine cells (EECs) are the primary sensory cells that sense the gut luminal environment and secret hormones to regulate organ function. Recent studies revealed that vagal afferent neurons are connected to EECs and relay sensory information
Autor:
Yuta Yoshioka, Taichi Nakatani, Atsuhiro Yamamichi, Takumi Fukumoto, Tatsuya Takemoto, Toshihiro Uesaka, Yuko Bitoh, Hideki Enomoto, Mitsuhiro Iwasaki, Kosaku Maeda
Publikováno v:
Development, Growth & Differentiation. 62:214-222
Missense mutations of the RET gene have been identified in both multiple endocrine neoplasia (MEN) type 2A/B and Hirschsprung disease (HSCR: congenital absence of the enteric nervous system, ENS). Current consensus holds that MEN2A/B and HSCR are cau
Autor:
Mukhamad Sunardi, Keisuke Ito, Yuya Sato, Toshihiro Uesaka, Mitsuhiro Iwasaki, Hideki Enomoto
Publikováno v:
Cellular and molecular gastroenterology and hepatology.
Background & Aims: Hirschsprung disease (HSCR) is a congenital disorder characterized by the absence of the enteric nervous system (ENS). HSCR potentially involves multiple gene aberrations and displays complex patterns of inheritance. Mutations of t
Publikováno v:
Development, growthdifferentiationREFERENCES. 63(6)
The GDNF Family Ligands (GFLs) regulate neural development and kidney organogenesis by activating the RET receptor tyrosine kinase. Many RET-dependent developmental processes involve long-distance cell-cell communications or cell polarity, which incl
Autor:
Mitsumasa Okamoto, Mayumi Nagashimada, Miho Kihara, Hideki Enomoto, Toshihiro Uesaka, Hiroshi Kiyonari, Yoshihiro Tsuda
Publikováno v:
GliaREFERENCES. 69(11)
Hirschsprung disease (HSCR) is characterized by congenital absence of enteric neurons in distal portions of the gut. Although recent studies identified Schwann cell precursors (SCPs) as a novel cellular source of enteric neurons, it is unknown how SC
Publikováno v:
eNeuro
Mutations of the gene encoding the RET tyrosine kinase causes Hirschsprung’s disease (HSCR) and medullary thyroid carcinoma (MTC). Current consensus holds that HSCR and MTC are induced by inactivating and activating RET mutations, respectively. How
Publikováno v:
eNeuro. 8(3):0534
Mutations of the gene encoding the RET tyrosine kinase causes Hirschsprung disease (HSCR) and medullary thyroid carcinoma (MTC). Current consensus holds that HSCR and MTC are induced by inactivating and activating RET mutations, respectively. However
Autor:
Hideki Enomoto, Thomas Müller, Alan J. Burns, Franck Boismoreau, Carmen Birchmeier, Zoubida Chettouh, Isabel Espinosa-Medina, Jean-François Brunet, Ben Jevans
Publikováno v:
Proceedings of the National Academy of Sciences of the U.S.A., 114(45), 11980-11985. National Academy of Sciences
Most of the enteric nervous system derives from the "vagal" neural crest, lying at the level of somites 1-7, which invades the digestive tract rostro-caudally from the foregut to the hindgut. Little is known about the initial phase of this colonizati
Publikováno v:
genesis. 57
Neuroblastoma, an embryonal tumor arising from the sympathetic ganglia and adrenal medulla, is among the most intractable pediatric cancers. Although a variety of genetic changes have been identified in neuroblastoma, how they contribute to its patho
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1976
Time-lapse imaging of gut explants from embryonic mice in which neural crest-derived cells express fluorescent proteins allows the behavior of enteric neural crest cells to be observed and analyzed. Explants of embryonic gut are dissected, mounted on