Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hideki, Wakasugi"'
Autor:
Kazuya Ishiguro, Hiroshi Kitajima, Takeshi Niinuma, Tadao Ishida, Reo Maruyama, Hiroshi Ikeda, Toshiaki Hayashi, Hajime Sasaki, Hideki Wakasugi, Koyo Nishiyama, Tetsuya Shindo, Eiichiro Yamamoto, Masahiro Kai, Yasushi Sasaki, Takashi Tokino, Hiroshi Nakase, Hiromu Suzuki
Publikováno v:
Haematologica, Vol 104, Iss 1 (2019)
Epigenetic alterations play an important role in the pathogenesis in multiple myeloma, but their biological and clinical relevance is not fully understood. Here, we show that DOT1L, which catalyzes methylation of histone H3 lysine 79, is required for
Externí odkaz:
https://doaj.org/article/57017ffa7cd249f995242f98fb6b1f02
Autor:
Hajime, SASAKI, Hiroshi, KITAJIMA, Takeshi, NIINUMA, Hideki, WAKASUGI, Kazuya, ISHIGURO, Akira, YOROZU, Gouta, SUDO, Tomo, HATAHIRA, Noriyuki, AKUTU, Eiichiro, YAMAMOTO, Masahiro, KAI, Shigeru, SASAKI, Hiroshi, NAKASE, Hiromu, SUZUKI
Publikováno v:
札幌医学雑誌=The Sapporo Medical Journal. 88(1-6):21-35
Bromodomain and extra terminal (BET) family proteins, which include BRD4, are readers of histone acetyl-lysines and key regulators of gene transcription. BRD4 inhibitors exert anti-tumor effects in various cancers, including hepatocellular carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::dc0e6b00e4e87b821c5a1add53aaa3c9
https://sapmed.repo.nii.ac.jp/records/16508
https://sapmed.repo.nii.ac.jp/records/16508
Autor:
Michihiro Suzuki, Hiroyuki Yamamoto, Hideaki Takahashi, S Iwabuchi, Yasushi Sasaki, Masayuki Takagi, Takeshi Niinuma, Hiroshi Yotsuyanagi, Chiaki Okuse, Yasuhito Tanaka, Naoki Matsumoto, Norie Yamada, Ritsuko Oikawa, Takeya Tsutsumi, Takeshi Matsui, Takehito Otsubo, Takashi Tokino, Hideki Wakasugi, Hiromu Suzuki, Noriyuki Akutsu, Hiroshi Nakase, Hajime Sasaki, Yuko Takeba, Shigeru Sasaki, Jong-Hon Kang, Eiichiro Yamamoto, Masayuki Nakano, Yasushi Ariizumi, Masahiro Kai, Hiroshi Kitajima, Fumio Itoh
Publikováno v:
Cancer Letters. 434:91-100
Hepatitis B virus (HBV) infection is a major cause of hepatocellular carcinoma (HCC). Nucleos(t)ide analogue (NA) therapy effectively reduces the incidence of HCC, but it does not completely prevent the disease. Here, we show that dysregulation of mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ade05273539e3b656a33ce8b0be76f
https://doi.org/10.1016/j.canlet.2018.07.019
https://doi.org/10.1016/j.canlet.2018.07.019
Autor:
Toshiaki Hayashi, Takashi Tokino, Hideki Wakasugi, Hiroshi Nakase, Hajime Sasaki, Hiroshi Ikeda, Koyo Nishiyama, Reo Maruyama, Yasushi Sasaki, Tadao Ishida, Eiichiro Yamamoto, Tetsuya Shindo, Kazuya Ishiguro, Hiromu Suzuki, Masahiro Kai, Hiroshi Kitajima, Takeshi Niinuma
Publikováno v:
Haematologica
Epigenetic alterations play an important role in the pathogenesis in multiple myeloma, but their biological and clinical relevance is not fully understood. Here, we show that DOT1L, which catalyzes methylation of histone H3 lysine 79, is required for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b1e5bb5c03b2c4233f0c695efa62ee
https://doi.org/10.3324/haematol.2018.191262
https://doi.org/10.3324/haematol.2018.191262
Autor:
Miki Itoh, Kazuhiko Yonezawa, Kazuya Suzuki, Yasuhisa Shinomura, Keiko Ushijima, Yasutaka Matsunaga, Kenichi Fujii, Akira Goto, Takashi Abe, Ayako Itoh, Hideki Wakasugi
Publikováno v:
Hepatology Research. 42:103-109
Klinefelter's syndrome (KS) is a unique physical condition characterized by tall stature, eunuchoid body proportions, gynecomastia, and azoospermia, in addition to an extra X chromosome. In contrast to the original description, symptoms or physical f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::467e406a02637298ef54b6b72a13ebef
https://doi.org/10.1111/j.1872-034x.2011.00903.x
https://doi.org/10.1111/j.1872-034x.2011.00903.x
Autor:
Hideki Wakasugi, Yasuhisa Shinomura, Yasutaka Sukawa, Hiroki Takahashi, Motohisa Yamamoto, Chisako Suzuki, Kohzoh Imai, Hiroyuki Yamamoto, Yasuyoshi Naishiro, Mayuko Saito
Publikováno v:
Modern Rheumatology. 17:72-74
A 74-year-old Japanese woman was diagnosed with rheumatoid arthritis due to polyarthralgia. She was prescribed various disease-modifying anti-rheumatic drugs, but most of them were discontinued because of side effects or poor effectiveness. She was r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5801bbae062b2c2bc21191f72734536b
https://doi.org/10.3109/s10165-006-0530-2
https://doi.org/10.3109/s10165-006-0530-2
Autor:
Masayo Motoya, Noriyuki Akutsu, Hiroshi Nakase, Ayako Ito, Shigeru Sasaki, Masahiro Shitani, Hideki Wakasugi, Keisuke Ishigami
Publikováno v:
Pancreatology. 16:S50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8f2fb92ef3c0c80ba3e0223c76b36b1
https://doi.org/10.1016/j.pan.2016.06.186
https://doi.org/10.1016/j.pan.2016.06.186
Autor:
Akira, Goto, Miki, Itoh, Hideki, Wakasugi, Shinichi, Kanno, Takashi, Yabana, Kei, Mitsuhashi, Takeya, Adachi, Yoshihiro, Kondo, Takashi, Suzuki, Yasuhisa, Shinomura
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 39(10)
S-1 and capecitabine are orally administered fluoropyridines reported to be effective in the treatment of advanced gastric cancer(AGC). In fact, both S-1/CDDP and capecitabine/CDDP are considered to be the standard first-line treatments for AGC.Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42a601fda70bcfa700bb88ec35a4b1e5
https://pubmed.ncbi.nlm.nih.gov/23064073
https://pubmed.ncbi.nlm.nih.gov/23064073
Autor:
Yasutaka, Matsunaga, Akira, Goto, Hideki, Wakasugi, Ayako, Itoh, Kazuhiko, Yonezawa, Miki, Itoh, Kenichi, Fujii, Kazuya, Suzuki, Takashi, Abe, Keiko, Ushijima, Yasuhisa, Shinomura
Publikováno v:
Hepatology research : the official journal of the Japan Society of Hepatology. 42(1)
Klinefelter's syndrome (KS) is a unique physical condition characterized by tall stature, eunuchoid body proportions, gynecomastia, and azoospermia, in addition to an extra X chromosome. In contrast to the original description, symptoms or physical f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ead17487e0a02270fb8d43284d97d4f
https://pubmed.ncbi.nlm.nih.gov/22175800
https://pubmed.ncbi.nlm.nih.gov/22175800
Autor:
Akira, Goto, Yasutaka, Sukawa, Hisayoshi, Igarashi, Kei, Onodera, Yuka, Aoki, Kazuya, Suzuki, Kazuhiko, Yonezawa, Atsushi, Yawata, Toshihisa, Kobayashi, Hiroyuki, Kaneto, Haruo, Shimizu, Hideki, Wakasugi, Yasutaka, Matsunaga, Miki, Itoh, Hiroyuki, Okuda, Yoshiaki, Arimura, Yasuhisa, Shinomura
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 38(9)
S-1, an oral fluoropyrimidine, is one of the standard chemotherapeutic agents for the treatment of metastatic gastric cancer(MGC). However, the most effective second-line regimen after failure of treatment with first-line agents such as S-1 is yet to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71cd23f6b1f0a64daf0a1370a3776c6d
https://pubmed.ncbi.nlm.nih.gov/21945893
https://pubmed.ncbi.nlm.nih.gov/21945893