Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Hideki, Masaki"'
Autor:
Hisato Nagano, Naoaki Mizuno, Hideyuki Sato, Eiji Mizutani, Ayaka Yanagida, Mayuko Kano, Mariko Kasai, Hiromi Yamamoto, Motoo Watanabe, Fabian Suchy, Hideki Masaki, Hiromitsu Nakauchi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Autologous skin grafting is a standard treatment for skin defects such as burns. No artificial skin substitutes are functionally equivalent to autologous skin grafts. The cultured epidermis lacks the dermis and does not engraft deep wounds.
Externí odkaz:
https://doaj.org/article/73c8b6c09efa46b89223f990ccfd8ee1
Autor:
Kazuto Yamazaki, Kenji Kubara, Satoko Ishii, Peng Li, Ryo Dairiki, Taro Hihara, Yuta Ishizuka, Yukina Izumi, Minoru Kumai, Tsutomu Kamisako, Hiroyoshi Ishizaki, Hideyuki Sato, Hideki Masaki, Naoaki Mizuno, Kaoru Mitsuhashi, Masashi Ito, Sanae Hamanaka, Tomoyuki Yamaguchi, Motoo Watanabe, Fumihiro Sugiyama, Hiromitsu Nakauchi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Blastocyst complementation is an intriguing way of generating humanized animals for organ preparation in regenerative medicine and establishing novel models for drug development. Confirming that complemented organs and cells work normally in
Externí odkaz:
https://doaj.org/article/83f9324b5cc14be682f2858dae6bd952
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Pancreas (and islet) transplantation is the only curative treatment for type 1 diabetes patients whose β-cell functions have been abolished. However, the lack of donor organs has been the major hurdle to save a large number of patients. Therefore, t
Externí odkaz:
https://doaj.org/article/df62a140f704412bbb4d2e633d4911f8
Autor:
Denise Zujur, Kosuke Kanke, Shoko Onodera, Shoichiro Tani, Jenny Lai, Toshifumi Azuma, Xiaonan Xin, Alexander C. Lichtler, David W. Rowe, Taku Saito, Sakae Tanaka, Hideki Masaki, Hiromitsu Nakauchi, Ung-il Chung, Hironori Hojo, Shinsuke Ohba
Publikováno v:
Regenerative Therapy, Vol 14, Iss , Pp 19-31 (2020)
Clinically relevant human induced pluripotent stem cell (hiPSC) derivatives require efficient protocols to differentiate hiPSCs into specific lineages. Here we developed a fully defined xeno-free strategy to direct hiPSCs toward osteoblasts within 21
Externí odkaz:
https://doaj.org/article/06a2c4f04f66498f94f1a291761848bf
Autor:
Hitomi Matsunari, Masahito Watanabe, Koki Hasegawa, Ayuko Uchikura, Kazuaki Nakano, Kazuhiro Umeyama, Hideki Masaki, Sanae Hamanaka, Tomoyuki Yamaguchi, Masaki Nagaya, Ryuichi Nishinakamura, Hiromitsu Nakauchi, Hiroshi Nagashima
Publikováno v:
Stem Cell Reports, Vol 14, Iss 1, Pp 21-33 (2020)
Summary: We have previously established a concept of developing exogenic pancreas in a genetically modified pig fetus with an apancreatic trait, thereby proposing the possibility of in vivo generation of functional human organs in xenogenic large ani
Externí odkaz:
https://doaj.org/article/f09ad79609f645288e079c1b4be8880b
Autor:
Manabu Kawata, Daisuke Mori, Kosuke Kanke, Hironori Hojo, Shinsuke Ohba, Ung-il Chung, Fumiko Yano, Hideki Masaki, Makoto Otsu, Hiromitsu Nakauchi, Sakae Tanaka, Taku Saito
Publikováno v:
Stem Cell Reports, Vol 13, Iss 3, Pp 530-544 (2019)
Summary: A simple induction protocol to differentiate chondrocytes from pluripotent stem cells (PSCs) using small-molecule compounds is beneficial for cartilage regenerative medicine and mechanistic studies of chondrogenesis. Here, we demonstrate tha
Externí odkaz:
https://doaj.org/article/2dc64c25609b46b1a78010c2c0ad39fe
Autor:
Teppei Goto, Hiromasa Hara, Makoto Sanbo, Hideki Masaki, Hideyuki Sato, Tomoyuki Yamaguchi, Shinichi Hochi, Toshihiro Kobayashi, Hiromitsu Nakauchi, Masumi Hirabayashi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
The use of pluripotent-stem cell derived organs for transplantation would be promising, if organs can be grown in a suitable host. Here, the authors use interspecific blastocyst complementation to generate a mouse pluripotent stem cell-derived kidney
Externí odkaz:
https://doaj.org/article/37e5f190bd684e10aa522b392a114893
Autor:
Sanae Hamanaka, Ayumi Umino, Hideyuki Sato, Tomonari Hayama, Ayaka Yanagida, Naoaki Mizuno, Toshihiro Kobayashi, Mariko Kasai, Fabian Patrik Suchy, Satoshi Yamazaki, Hideki Masaki, Tomoyuki Yamaguchi, Hiromitsu Nakauchi
Publikováno v:
Stem Cell Reports, Vol 11, Iss 4, Pp 988-997 (2018)
Summary: In the case of organ transplantation accompanied by vascular anastomosis, major histocompatibility complex mismatched vascular endothelial cells become a target for graft rejection. Production of a rejection-free, transplantable organ, there
Externí odkaz:
https://doaj.org/article/b52e9198d5664032b9d80ab01427a4fe
Autor:
Hideyuki Murayama, Hideki Masaki, Hideyuki Sato, Tomonari Hayama, Tomoyuki Yamaguchi, Hiromitsu Nakauchi
Publikováno v:
Stem Cell Reports, Vol 4, Iss 1, Pp 103-113 (2015)
Summary: Epiblast stem cells (EpiSCs) in mice and rats are primed pluripotent stem cells (PSCs). They barely contribute to chimeric embryos when injected into blastocysts. Reprogramming of EpiSCs to embryonic stem cell (ESC)-like cells (rESCs) may oc
Externí odkaz:
https://doaj.org/article/573a6c42164949feacb983f800d1bbcc
Autor:
Kosuke Kanke, Hideki Masaki, Taku Saito, Yuske Komiyama, Hironori Hojo, Hiromitsu Nakauchi, Alexander C. Lichtler, Tsuyoshi Takato, Ung-il Chung, Shinsuke Ohba
Publikováno v:
Stem Cell Reports, Vol 2, Iss 6, Pp 751-760 (2014)
Pluripotent stem cells are a promising tool for mechanistic studies of tissue development, drug screening, and cell-based therapies. Here, we report an effective and mass-producing strategy for the stepwise differentiation of mouse embryonic stem cel
Externí odkaz:
https://doaj.org/article/43c7fd868ce440ed8c67b087c0f8c37d