Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Hidekazu Kitada"'
Autor:
Seiji Kodama, Ikuo Fujii, Masahiro Oguri, Toshio Nishihara, Ikuhiko Nakase, Kenji Kono, Sihyun Ham, Eiji Yuba, Haeri Im, Jong Young Joung, Sunhee Cho, Daisuke Fujiwara, Hidekazu Kitada, Kazunori Shiraishi, Masataka Michigami
Publikováno v:
Angewandte Chemie International Edition. 55:10612-10615
The design of inhibitors of intracellular protein-protein interactions (PPIs) remains a challenge in chemical biology and drug discovery. We propose a cyclized helix-loop-helix (cHLH) peptide as a scaffold for generating cell-permeable PPI inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e22550ca301d3a6b22a8dedb8ab765d
https://doi.org/10.1002/anie.201603230
https://doi.org/10.1002/anie.201603230
Publikováno v:
Biopolymers. 106:415-421
Conformationally constrained peptides have been developed as an inhibitor for protein-protein interactions (PPIs), and we have de novo designed cyclized helix-loop-helix (cHLH) peptide with a disulfide bond consisting of 40 amino acids to generate mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::494560bf38933343807215d5f0a026a5
https://doi.org/10.1002/bip.22826
https://doi.org/10.1002/bip.22826
Publikováno v:
Biopolymers. 106(4)
Conformationally constrained peptides have been developed as an inhibitor for protein-protein interactions (PPIs), and we have de novo designed cyclized helix-loop-helix (cHLH) peptide with a disulfide bond consisting of 40 amino acids to generate mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d564e54d5c93b47e2b76f8466227c693
https://pubmed.ncbi.nlm.nih.gov/26917088
https://pubmed.ncbi.nlm.nih.gov/26917088