Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Hidekazu Inoue"'
Autor:
Shunsuke Fukui MD, Hideo Wada MD, PhD, Kohei Ikeda MD, Mayu Kobayashi MD, Yasuaki Shimada MD, Yuuichi Nakazawa MD, Hiroki Mizutani MD, Yuhuko Ichikawa, Yuuki Nishiura MD, Isao Moritani MD, PhD, Yutaka Yamanaka MD, Hidekazu Inoue MD, PhD, Motomu Shimaoka MD, PhD, Hideto Shimpo MD, PhD, Katsuya Shiraki MD, PhD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 30 (2024)
Background: Although hepatocellular carcinoma (HCC) is frequently associated with thrombosis, it is also associated with liver cirrhosis (LC) which causes hemostatic abnormalities. Therefore, hemostatic abnormalities in patients with HCC were examine
Externí odkaz:
https://doaj.org/article/eae6b982e68a4eae922ff717ba94ffd5
Autor:
Daisuke Suga, Hiroki Mizutani, Shunsuke Fukui, Mayu Kobayashi, Yasuaki Shimada, Yuuichi Nakazawa, Yuuki Nishiura, Yuuya Kawasaki, Isao Moritani, Yutaka Yamanaka, Hidekazu Inoue, Eiki Ojima, Yasuhiko Mohri, Hayato Nakagawa, Kaoru Dohi, Kei Takaba, Hideo Wada, Katsuya Shiraki
Publikováno v:
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Gut pathological microbial imbalance or dysbiosis is closely associated with colorectal cancer. Although there are observable differences in molecular and clinical characteristics between patients with right- and left-sided colon
Externí odkaz:
https://doaj.org/article/5edae0560d5b458b9887178703df1910
Autor:
Hideo Wada, Akitaka Yamamoto, Masaki Tomida, Yuhuko Ichikawa, Minoru Ezaki, Jun Masuda, Masamichi Yoshida, Shunsuke Fukui, Isao Moritani, Hidekazu Inoue, Katsuya Shiraki, Kei Suzuki, Hiroshi Imai, Motomu Shimaoka, Hideto Shimpo
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 4; Pages: 1028
Background. The diagnostic criteria for disseminated intravascular coagulation (DIC) vary and are complicated and the cut-off values are different. Simple and quick diagnostic criteria for DIC are required in physicians for critical care. Material an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d504e86430321836819d4738810305
https://pubmed.ncbi.nlm.nih.gov/35207302
https://pubmed.ncbi.nlm.nih.gov/35207302
Autor:
Daisuke Suga, Hiroki Mizutani, Shunsuke Fukui, Mayu Kobayashi, Yasuaki Shimada, Yuuichi Nakazawa, Yuuki Nishiura, Yuuya Kawasaki, Isao Moritani, Yutaka Yamanaka, Hidekazu Inoue, Eiki Ojima, Yasuhiko Mohri, Hayato Nakagawa, Kaoru Dohi, Kei Takaba, Hideo Wada, Katsuya Shiraki
Publikováno v:
BMC gastroenterology. 22(1)
Background Gut pathological microbial imbalance or dysbiosis is closely associated with colorectal cancer. Although there are observable differences in molecular and clinical characteristics between patients with right- and left-sided colon cancer, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec74c259262f2a4513ac3697e442d15
https://pubmed.ncbi.nlm.nih.gov/35752764
https://pubmed.ncbi.nlm.nih.gov/35752764
Autor:
Hideto Shimpo, Hideo Wada, Isao Moritani, Katsuya Shiraki, Hidekazu Inoue, Mayu Kobayashi, Motomu Shimaoka, Hiroki Mizutani, Yuhuko Ichikawa, Shunsuke Fukui
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 10, Iss 5352, p 5352 (2021)
Volume 10
Issue 22
Journal of Clinical Medicine, Vol 10, Iss 5352, p 5352 (2021)
Volume 10
Issue 22
(1) Objective: hypercoagulability in patients with malignant neoplasm were evaluated to examine the relationship with thrombosis. (2) Methods: clot waveform analysis (CWA)—activated partial thromboplastin time (APTT) and CWA—small amount of tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77b6aad16aeaaa003f293274f129009
http://europepmc.org/articles/PMC8618625
http://europepmc.org/articles/PMC8618625
Autor:
Shunsuke Fukui, Yuhuko Ichikawa, Masaki Tomida, Masamichi Yoshida, Hikaru Mizuno, Isao Moritani, Akitaka Yamamoto, Hideo Wada, Katsuya Shiraki, Jun Masuda, Hideto Shimpo, Katsutoshi Makino, Shuji Kodama, Hidekazu Inoue
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 10, Iss 3775, p 3775 (2021)
Volume 10
Issue 17
Journal of Clinical Medicine, Vol 10, Iss 3775, p 3775 (2021)
Volume 10
Issue 17
Object: Although many Japanese patients infected with coronavirus disease 2019 (COVID-19) only experience mild symptoms, in some cases a patient’s condition deteriorates, resulting in a poor outcome. This study examines the behavior of biomarkers i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ae293b46b9855f49494f712ecab7e9
https://pubmed.ncbi.nlm.nih.gov/34501223
https://pubmed.ncbi.nlm.nih.gov/34501223
Autor:
Nobuhiro Narii, Yoshiari Shimmyo, Kenji Murata, Tetsuya Toba, Hidekazu Inoue, Takahiro Matsumoto, Hiroki Sakai, Naohiro Takemoto, Yoshiyuki Igawa
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:2332-2337
To avoid production of a phospholipidosis-inducing metabolite, we replaced the amide structure of SUN13837 (1) with a 1,2,3-triazole. The resulting 1,2,3-triazole analog of 1 (compound 2) displayed greater neuroprotective activity than 1. Structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baee5e1f6c21724d69605ac50218b352
https://doi.org/10.1016/j.bmcl.2019.06.016
https://doi.org/10.1016/j.bmcl.2019.06.016
Autor:
Hidekazu Inoue, Kenji Murata, Takeo Kawabata, Naohiro Takemoto, Takahiro Matsumoto, Hiroki Sakai, Tetsuya Toba
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(18)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1f1baadcd34a48dbc234784b868e6e
https://pubmed.ncbi.nlm.nih.gov/32044185
https://pubmed.ncbi.nlm.nih.gov/32044185
Autor:
Yoshiari Shimmyo, Naohiro Takemoto, Yoshiyuki Igawa, Shinya Ueno, Nobuhiro Narii, Kenji Murata, Tetsuya Toba, Hidekazu Inoue, Hiroki Sakai
Publikováno v:
Bioorganicmedicinal chemistry. 28(14)
SUN13837 (1), a fibroblast growth factor receptor modulator, has been an attractive candidate for treating neurodegenerative diseases. However, one of its metabolites, N-benzyl-4-(methylamino)piperidine (BMP), turned out to possess phospholipidosis-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b7a19f61b8950e9f00b9775a622d5b
https://pubmed.ncbi.nlm.nih.gov/32616184
https://pubmed.ncbi.nlm.nih.gov/32616184
Autor:
Masahiro Ota, Yoshimi Takata, Kanae Suzuki, Makoto Suzuki, Yasuhide Hirota, Kaori Ono, Takashi Asahi, Shinji Tsutsumi, Hidekazu Inoue, Junya Kawai, Tadashi Toki, Sachiko Takaishi, Kiyoshi Nakayama, Hitoshi Ohki, Takashi Shimada, Satoshi Matsui
Publikováno v:
Journal of medicinal chemistry. 62(22)
We report the discovery of a potent and isozyme-selective MTHFD2 inhibitor, DS18561882 (2). Through investigation of the substituents on our tricyclic coumarin scaffold (1,2,3,4-tetrahydrochromeno[...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc68b85cee6f34ade62e2d05e67507c5
https://pubmed.ncbi.nlm.nih.gov/31638799
https://pubmed.ncbi.nlm.nih.gov/31638799