Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hidekazu Aratani"'
Publikováno v:
International Archives of Allergy and Immunology. 96:238-243
Effect of Y-20811 on airway hyperresponsiveness was studied in sensitized guinea pigs. Airway hyperresponsiveness to acetylcholine (ACh) reached maximum 7 h after antigen challenge in guinea pigs sensitized actively. Y-20811 (0.3–3 mg/kg) administe
Publikováno v:
International archives of allergy and immunology. 102(3)
We examined whether oral administration of allergen induced bronchoconstriction in sensitized guinea pigs and investigated the mechanisms of bronchoconstriction. The animals had been immunized intraperitoneally with a mixture of Ascaris suum extract
Publikováno v:
Japanese Journal of Pharmacology. 61:163
Publikováno v:
Japanese Journal of Pharmacology. 47:200-203
Publikováno v:
The Journal of Biochemistry. 96:107-115
An aminopeptidase was purified about 4,000-fold from the clarified homogenate of bovine leukocytes by a series of column chromatographies on DEAE-cellulose, hydroxyapatite, Sephadex G-150, and DEAE-Toyopearl. The purified enzyme had a specific activi
Publikováno v:
Folia Pharmacologica Japonica. 89:129-137
Effect of a non-steroidal anti-inflammatory drug, pranoprofen (PPF), on sodium urate crystal-induced inflammation was investigated in comparison with standard drugs for treating acute gout in experimental animals. PPF inhibited sodium urate crystal-i
Autor:
Michio Terasawa, Yutaka Maruyama, Hidekazu Aratani, Yukari Nagaoka, Yoshinori Iwahisa, Tomonori Imayoshi
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 89(3)
The mechanism of the inhibitory effect of pranoprofen on sodium urate crystal-induced inflammation was investigated with several inflammatory parameters using leucocytes stimulated with sodium urate crystals in vitro. At 10(-5) M, pranoprofen tended
Autor:
Satoru Makisumi, Shuji Kawata, Koichi Mizusaki, Yoshihiro Hatanaka, Magobei Yamamoto, Hideaki Tsunematsu, Hidekazu Aratani
Publikováno v:
Chemicalpharmaceutical bulletin. 36(3)
β-Naphthylamides of p-guanidino-L-phenylalanine (GPA) and p-guanidino-DL-phenylglycine (GPG) were synthesized and tested as substrates of bovine leukocyte aminopeptidase (BL-APase) and porcine liver aminopeptidase B (PL-APaseB) in comparison with L-