Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Hidekata Yasuoka"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Neutrophils form neutrophil extracellular traps (NETs), which are involved in the pathogenesis of ANCA-associated vasculitis (AAV). Recent reports suggest that platelets stimulated via toll-like receptor (TLR) pathways can induce NETs format
Externí odkaz:
https://doaj.org/article/f64033369c8343fbb1ed13579f2a4229
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-10 (2020)
Abstract Background Interstitial lung disease (ILD) is a serious complication of connective tissue diseases (CTDs). Although immune dysregulation triggered by genetic and environmental factors is thought to provoke inflammation and subsequent fibrosi
Externí odkaz:
https://doaj.org/article/5865c9291f204c879b58630a1b58bb1a
Autor:
Yasushi Kondo, Katsuya Suzuki, Yumiko Inoue, Koumei Sakata, Chihiro Takahashi, Masaru Takeshita, Yoshiaki Kassai, Takahiro Miyazaki, Rimpei Morita, Yasuo Niki, Yuko Kaneko, Hidekata Yasuoka, Kunihiro Yamaoka, Akihiko Yoshimura, Tsutomu Takeuchi
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-8 (2019)
Abstract Background Ultrasonography (US) can directly demonstrate joint inflammation, including grayscale (GS) signs of synovial hypertrophy and power Doppler (PD) techniques to demonstrate increased blood flow and vascularization. Recently, echogeni
Externí odkaz:
https://doaj.org/article/39d3a86e0db349e081c062736a2355c7
Autor:
Mitsuhiro Akiyama, Katsuya Suzuki, Keiko Yoshimoto, Hidekata Yasuoka, Yuko Kaneko, Tsutomu Takeuchi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
ObjectivesMultiple studies suggest that interleukin (IL)-21 plays a pivotal role in the differentiation of B cells and activation of cytotoxic T cells and is involved in the pathogenesis of IgG4-related disease (IgG4-RD). T cell immunoreceptor with i
Externí odkaz:
https://doaj.org/article/6553d033abbd4b3095693a0231368d16
Publikováno v:
Inflammation and Regeneration, Vol 38, Iss 1, Pp 1-5 (2018)
Abstract Background In granulomatosis with polyangiitis (GPA), peripheral nerve involvement is common but central nervous system (CNS) involvement is extremely rare and treatment strategy has not been established. We report a case of intravenous cycl
Externí odkaz:
https://doaj.org/article/61b41bc5cd5645af9776a7034e7217b5
Autor:
Shinya Tasaki, Katsuya Suzuki, Yoshiaki Kassai, Masaru Takeshita, Atsuko Murota, Yasushi Kondo, Tatsuya Ando, Yusuke Nakayama, Yuumi Okuzono, Maiko Takiguchi, Rina Kurisu, Takahiro Miyazaki, Keiko Yoshimoto, Hidekata Yasuoka, Kunihiro Yamaoka, Rimpei Morita, Akihiko Yoshimura, Hiroyoshi Toyoshiba, Tsutomu Takeuchi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Little information is available on molecular changes in response to treatment of rheumatoid arthritis (RA). Here the authors report a multi-omics study collecting patients' transcriptome, proteome, and immunophenotype data to help understand the impa
Externí odkaz:
https://doaj.org/article/6c7bcbecbfa5477e86bcbca7581072ed
Autor:
Hidekata Yasuoka
Publikováno v:
Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, Vol 2015, Iss Suppl. 1, Pp 97-110 (2016)
Externí odkaz:
https://doaj.org/article/e2fdac857aa847069c631f119b5343c6
Autor:
Hidekata Yasuoka
Publikováno v:
Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, Vol 9s1 (2015)
Systemic sclerosis (SSc) is a disorder characterized by immune dysfunction, microvascular injury, and fibrosis. Organ involvement in patients with SSc is variable; however, pulmonary involvement occurs in up to 90% of patients with SSc. Interstitial
Externí odkaz:
https://doaj.org/article/90622c17e29f4240a4d9feff0732df4b
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87754 (2014)
Systemic sclerosis (SSc) is characterized by excessive fibrosis of the skin and internal organs due to fibroblast proliferation and excessive production of extracellular matrix (ECM). We have shown that insulin-like growth factor binding protein (IGF
Externí odkaz:
https://doaj.org/article/86c7f3a668e748f7b69ef6a4b4366da7
Autor:
Kenta Misaki, Naoto Tamura, Takanori Azuma, Koichiro Shinoda, Masao Tanaka, Hiroshi Fujiwara, Hideki Tsuboi, Tsuyoshi Kasama, Ryusuke Yoshimi, Tadamasa Hanyu, Yoshiaki Kusaka, Makoto Hirao, Makoto Onishi, Ayumi Uchino, Tomomasa Izumiyama, Kwang-Seok Yang, Noriyoshi Ogawa, Kiyoshi Matsui, Kazuhiro Kurasawa, Satoshi Kawai, Hidekata Yasuoka, Noriaki Okumura, Yo Ueda, Eiichi Tanaka, Eisuke Inoue, Katsuki Tsuritani, Shigeru Matsumoto, Hisashi Yamanaka, Masayoshi Harigai
Publikováno v:
Modern Rheumatology.
Objective To investigate the associations of disease duration and anti-cyclic citrullinated peptide antibody (ACPA) status with the effectiveness of abatacept in biologic-naïve patients with rheumatoid arthritis (RA) Methods We performed post-hoc an