Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Hidehito Mukai"'
Autor:
André Holdfeldt, Michael Gabl, Simon Lind, Huamei Forsman, Kodai Nishino, Jonas Mårtensson, Martina Sundqvist, Claes Dahlgren, Hidehito Mukai
Publikováno v:
The Journal of Immunology. 202:2710-2719
Similar to bacteria, synthesis of mitochondrial DNA–encoded proteins requires an N-formylated methionine to initiate translation. Thus, the N-formylated methionine peptides originating from mitochondria should be recognized as danger signals. To da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4151c17e05f79f04e40dcb522e4c1c94
https://doi.org/10.4049/jimmunol.1900060
https://doi.org/10.4049/jimmunol.1900060
Autor:
Keisuke Kamada, Tomoyuki Miyaji, Koji Ohura, Hidehito Mukai, Takayuki Marutani, Yoshiaki Kiso, Kodai Nishino
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 8
International Journal of Molecular Sciences, Vol 22, Iss 4084, p 4084 (2021)
Volume 22
Issue 8
International Journal of Molecular Sciences, Vol 22, Iss 4084, p 4084 (2021)
Mitocryptides are a novel family of endogenous neutrophil-activating peptides originating from various mitochondrial proteins. Mitocryptide-2 (MCT-2) is one of such neutrophil-activating peptides, and is produced as an N-formylated pentadecapeptide f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c08fda2ada07fb23c46e2a4261e6fd
https://pubmed.ncbi.nlm.nih.gov/33920954
https://pubmed.ncbi.nlm.nih.gov/33920954
Autor:
Hidehito Mukai, Koki Tsutsumi, Kodai Nishino, Hiroki Morikawa, Yoshiaki Kiso, Toshihiro Shimizu, Takenori Yamada, Takayuki Marutani, Tatsuya Hattori, Yoshisuke Nishi
Publikováno v:
Journal of Peptide Science. 23:610-617
We recently identified a novel family of neutrophil-activating peptides including mitocryptide-1 and mitocryptide-2 (MCT-2) that are endogenously produced from various mitochondrial proteins. Among them, MCT-2 is an N-formylated pentadecapeptide deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12929f0a6c9ffce411a2a84cc7fbfeda
https://doi.org/10.1002/psc.3000
https://doi.org/10.1002/psc.3000
Autor:
Koki Tsutsumi, Akihiko Harada, Yoshiaki Kiso, Kosuke Noguchi, Tatsuya Hattori, Hidehito Mukai, Yusuke Koike, Takayuki Marutani
Publikováno v:
Biopolymers. 106:580-587
Recently, much attention has been paid to "nonclassical" bioactive peptides, which are fragmented peptides simultaneously produced during maturation and degradation of various functional proteins. We identified many fragmented peptides derived from v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::676633d8507fb2cb50020377575d7eef
https://doi.org/10.1002/bip.22788
https://doi.org/10.1002/bip.22788
Autor:
Karin Christenson, Jonas Mårtensson, Michael Gabl, Huamei Forsman, André Holdfeldt, Hidehito Mukai, Simon Lind, Martina Sundqvist, Takayuki Marutani, Claes Dahlgren
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 200(9)
Phagocytic neutrophils express formyl peptide receptors (FPRs; FPR1 and FPR2) that distinctly recognize peptides starting with an N-formylated methionine (fMet). This is a hallmark of bacterial metabolism; similar to prokaryotes, the starting amino a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0c008ef94f15ffec0e5d986aaee27c
https://pubmed.ncbi.nlm.nih.gov/29602776
https://pubmed.ncbi.nlm.nih.gov/29602776
Autor:
Hidehito Mukai, Yoshiaki Kiso, Yoshisuke Nishi, Tatsuya Hattori, Takayuki Marutani, Kenta Nakashima
Publikováno v:
Biochemical and Biophysical Research Communications. 463:54-59
Mitocryptide-1 (MCT-1) is a novel neutrophil-activating peptide derived from mitochondrial cytochrome c oxidase subunit VIII, and its physiological role and involvement in various diseases have not yet been elucidated. Generating neutralizing antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff450e52f24bb6ad72be2a8cf275a491
https://doi.org/10.1016/j.bbrc.2015.05.016
https://doi.org/10.1016/j.bbrc.2015.05.016
Autor:
Tatsuya, Hattori, Takenori, Yamada, Hiroki, Morikawa, Takayuki, Marutani, Koki, Tsutsumi, Kodai, Nishino, Toshihiro, Shimizu, Yoshisuke, Nishi, Yoshiaki, Kiso, Hidehito, Mukai
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 23(7-8)
We recently identified a novel family of neutrophil-activating peptides including mitocryptide-1 and mitocryptide-2 (MCT-2) that are endogenously produced from various mitochondrial proteins. Among them, MCT-2 is an N-formylated pentadecapeptide deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4998f7b3b406a1800d025e9965153f18
https://pubmed.ncbi.nlm.nih.gov/28370673
https://pubmed.ncbi.nlm.nih.gov/28370673
Autor:
Masayuki Yamashita, Yoshiaki Kiso, Tomoya Nakanishi, Hiroyuki Kawashima, Kenichi Akaji, Hidehito Mukai, Youhei Sohma, Hitomi Kitamura
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:6323-6327
Inhibition of amyloid β peptide (Aβ) aggregation is a potential therapeutic approach to treat Alzheimer’s disease. We report that an O -acyl isopeptide of Aβ1–42 ( 1 ) containing an ester bond at the Gly 25 -Ser 26 moiety inhibits Aβ1–42 fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be31873a416dd38f5e6f207f54986ed
https://doi.org/10.1016/j.bmc.2013.08.062
https://doi.org/10.1016/j.bmc.2013.08.062
Autor:
Yoshiaki Kiso, Hiroyuki Kawashima, Moe Yamasaki, Atsuhiko Taniguchi, Masayuki Yamashita, Youhei Sohma, Kenichi Akaji, Hidehito Mukai
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:1326-1329
The use of water-soluble O -acyl isopeptides enabled us to investigate the biochemical properties of Aβ11–42 species, by preparing highly concentrated stock solutions after a pretreatment. Aβ11–42 and [Pyr 11 ]Aβ11–42 showed comparable aggre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cae5c1c054b4e81706dffb62041ecf69
https://doi.org/10.1016/j.bmcl.2012.12.082
https://doi.org/10.1016/j.bmcl.2012.12.082
Autor:
Hidehito Mukai, Yuta Hirayama, Taeko Kakizawa, Hui Wang, Youhei Sohma, Atsuhiko Taniguchi, Moe Yamasaki, Yoshiaki Kiso
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:3787-3792
The recently identified E22Δ-type amyloid β peptide (Aβ) mutants are reported to favor oligomerization over fibrillization and to exhibit more-potent synaptotoxicity than does wild-type (WT) Aβ. Aβ(E22Δ) mutants can thus be expected to serve as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ccfad08c6315d3e6b4346292226cbe6
https://doi.org/10.1016/j.bmc.2011.04.056
https://doi.org/10.1016/j.bmc.2011.04.056