Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hidehisa Sasaki"'
Autor:
Ichiro Tatsuno, Daiji Nagayama, Kei Endo, Noriko Ban, Takeyoshi Murano, Hidetoshi Kawana, Atsuhito Saiki, Takashi Yamaguchi, Yoh Miyashita, Ayako Nagumo, Kohji Shirai, Hidehisa Sasaki, Tomokazu Oyama, Shigeo Yamamura, Masahiro Ohira, Kiyoshi Sakuma, Yasuo Suzuki
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 20:494-502
Aim Probucol has antioxidant as well as cholesterol-lowering effects. We examined the effect of probucol on the progression of diabetic nephropathy. We named this study 'Sakura Study' after our hospital and city. Methods We performed a randomized, op
Autor:
Takashi Yamaguchi, Masahiro Ohhira, Tomokazu Oyama, D. Nagayama, Yoh Miyashita, Kohji Shirai, Hidetoshi Kawana, Kei Endo, Hidehisa Sasaki, Noriko Ban, Atsuhito Saiki
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 16:568-575
Aim: The three types of calcium channel blocker (CCB), L-, T- and N-type, possess heterogeneous actions on endothelial function and renal microvascular function. In the present study, we evaluated the effects of two CCBs, efonidipine and amlodipine,
Autor:
Mariko Ebisuno, Tomokazu Oyama, Koji Shirai, Hidehisa Sasaki, Murano Takeyoshi, Masahiro Ohira, Kei Endo, Yoh Miyashita, Atsuhito Saiki, Nobukiyo Koide
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 13:68-75
To clarify whether probucol and statins suppress oxidative stress in diabetic patients, we studied the effects of probucol and the statin atorvastatin on urinary 8-hydroxy-2'deoxyguanosine (8-OHdG) levels in diabetics with hypercholesterolemia. A ran
Autor:
Tomokazu Oyama, Masahiro Ohhira, Kohji Shirai, Saburou Kanai, Kiyoshi Sakuma, Toru Masaka, Hidehisa Sasaki, Yoh Miyashita
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 32:979-984
Metformin hydrochloride is known to decrease blood sugar levels by reducing insulin resistance and controlling glyconeogenesis in the liver. However, its action on serum lipid metabolism and prognostic factors in responsive and non-responsive cases a
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 31:544-552
The early detection of adverse drug reactions and pharmaceutical treatment for them are important in ensuring that drugs are administered safely. However, it is not easy for pharmacists to monitor all prescribed drugs for adverse drug reactions. In v
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 30:389-393
We felt that pharmacists should participate more actively in the evaluation of efficacy and safety in clinical trials. To improve the capability of pharmacists in this respect, we evaluated the support we gave to the investigators of the Japan EPA Li
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 30:804-811
Autor:
Toshiro Nema, Kohji Shirai, Saburo Kanai, Toshihiro Ishii, Yoh Miyashita, Hirokazu Doi, Yoshiaki Itoh, Hidehisa Sasaki
Publikováno v:
YAKUGAKU ZASSHI. 123:893-900
Early detection and early treatment of adverse drug reactions have recently become more important. It is natural that physicians should treat adverse drug reactions carefully, but it is also important to establish a system for their early systematic
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 28:415-424
A year-long prospective study was conducted to elucidate the effects of probucol, an anti-oxidative hypolipidemic agent, on the progression of diabetic nephropathy.A total of 152 diabetic outpatients with an urinary albumin level of 200mg/g·Cr or mo
Publikováno v:
Japanese Journal of Hospital Pharmacy. 26:584-591
The effects of an α-glucosidase inhibitor, acarbose on serum lipoproteins as well as hemoglobin A1c were studied in type 2 diabetes mellitus patients. Furthermore, the improving rates of hemoglobin A1c and serum lipoproteins were compared between th