Zobrazeno 1 - 10
of 386
pro vyhledávání: '"Hidehiro Uekusa"'
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33280- (2024)
Stability and potency improvement have been reported by reacting levofloxacin (LF) with citric acid (CA) in a (1:1) molar ratio. However, CA is known to be irritant to the gastrointestinal tract and should be minimized. In a novel approach, this expe
Externí odkaz:
https://doaj.org/article/2e43dcebec5d447ca7ed7c5632910070
Autor:
Ari Sartinah, Hidehiro Uekusa, Yuto Abekura, Slamet Ibrahim, Kusnandar Anggadiredja, Ilma Nugrahani
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e31548- (2024)
This study discusses the composition and structure determination of a new multicomponent system from antiinflammatory natural ingredients, consisting of piperine (Pip) and 4-hydroxybenzoic acid (HBA), named Pip-HBA. In addition, this research studied
Externí odkaz:
https://doaj.org/article/05732941c41f490aaa6539c9d627e1bb
Autor:
Indra Indra, Saleh Wikarsa, Yuda Prasetya Nugraha, Veinardi Suendo, Hidehiro Uekusa, Sundani Nurono Soewandhi
Publikováno v:
Journal of Pharmacy & Pharmacognosy Research, Vol 11, Iss 6, Pp 1137-1148 (2023)
Context: Co-crystal formation, a method for enhancing the physicochemical properties of active pharmaceutical ingredients (APIs), has gained traction in pharmaceutical research. However, the current landscape lacks comprehensive and dependable co-cry
Externí odkaz:
https://doaj.org/article/4de98d5f354a489384d6b45053a62689
Autor:
Yuda Prasetya Nugraha, I Gusti Ayu Nadia Prasta Unique, Tatsuki Miyake, Ridha Rahmah, Indra Indra, Sundani Nurono Soewandhi, Hidehiro Uekusa
Publikováno v:
Crystals, Vol 14, Iss 2, p 151 (2024)
Telmisartan is an anti-hypertensive drug that exhibits poor aqueous solubility. In this work, salt formation was utilized to address this issue. Three hydrochloride salts of telmisartan (TELHCl), a trihemihydrate hydrochloride salt (TELHCl-Hyd), and
Externí odkaz:
https://doaj.org/article/146f717f9de148ad81e6d79d02b4c3ee
Autor:
Pedro Paulo Ferreira da Rosa, Yuichi Kitagawa, Sunao Shoji, Hironaga Oyama, Keisuke Imaeda, Naofumi Nakayama, Koji Fushimi, Hidehiro Uekusa, Kosei Ueno, Hitoshi Goto, Yasuchika Hasegawa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Soft-crystals are molecular solids with highly ordered structures. Here, authors report the soft-crystal copolymerization of green-luminescent Tb(III) and yellow-luminescent Dy(III) complexes, and study the long-range energy transfer from one crystal
Externí odkaz:
https://doaj.org/article/bd06a74064d44b1fa154f8b88efc03d2
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 78, Iss 3, Pp 259-263 (2022)
The crystal structure of two multi-component crystals of ciprofloxacin [systematic name: 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)quinoline-3-carboxylic acid], a fluoroquinolone antibiotic, namely, ciprofloxacin 2,6-dihydroxybenzoate salt, C17H
Externí odkaz:
https://doaj.org/article/10e5b6ef7b404f0fb746dc60919dc26c
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 124 (2022)
Recently, solid-state engineering has become a promising approach to improving the stability and potency of antibiotics. Levofloxacin (LF) is a broad-spectrum fluoroquinolone antibiotic marketed in solid and solution dosage forms. However, this subst
Externí odkaz:
https://doaj.org/article/2f743e0810e44fcbb91ce89e874cde0c
Autor:
Kazuhiro Nawa, Kimihiko Tanaka, Nobuyuki Kurita, Taku J. Sato, Haruki Sugiyama, Hidehiro Uekusa, Seiko Ohira-Kawamura, Kenji Nakajima, Hidekazu Tanaka
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Topological edge states can emerge not only in a fermionic electron system but also in a bosonic system. Here, Nawa et al. report topologically nontrivial triplon bands in a two-dimensional dimerized quantum antiferromagnet Ba2CuSi2O6Cl2, suggesting
Externí odkaz:
https://doaj.org/article/3739820887e74dcf8e2d2efc420d2d3f
Autor:
Sunna Jung, Li Wang, Haruki Sugiyama, Hidehiro Uekusa, Tetsuro Katayama, Kenji Kamada, Toshiyuki Hamura, Naoto Tamai
Publikováno v:
The Journal of Physical Chemistry B. 127:4554-4561
Publikováno v:
Molecules, Vol 27, Iss 7, p 2166 (2022)
This research dealt with the composition, structure determination, stability, and antibiotic potency of a novel organic salt composed of levofloxacin (LF) and citric acid (CA), named levofloxacin-citrate (LC). After a stoichiometric proportion screen
Externí odkaz:
https://doaj.org/article/f3960fbba4a647f7a2f9718b73101cbd