Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Hidehiko Koizumi"'
Publikováno v:
eLife, Vol 11 (2022)
Previously our computational modeling studies (Phillips et al., 2019) proposed that neuronal persistent sodium current (INaP) and calcium-activated non-selective cation current (ICAN) are key biophysical factors that, respectively, generate inspirato
Externí odkaz:
https://doaj.org/article/dd1515b461b44c10a4cf3a5fd3aeda58
Publikováno v:
eLife, Vol 8 (2019)
An autorhythmic population of excitatory neurons in the brainstem pre-Bötzinger complex is a critical component of the mammalian respiratory oscillator. Two intrinsic neuronal biophysical mechanisms—a persistent sodium current ([Formula: see text]
Externí odkaz:
https://doaj.org/article/0f6806d48aff400796045da8626a121b
Autor:
Jessica Ausborn, Hidehiko Koizumi, William H Barnett, Tibin T John, Ruli Zhang, Yaroslav I Molkov, Jeffrey C Smith, Ilya A Rybak
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 4, p e1006148 (2018)
The circuit organization within the mammalian brainstem respiratory network, specifically within and between the pre-Bötzinger (pre-BötC) and Bötzinger (BötC) complexes, and the roles of these circuits in respiratory pattern generation are contin
Externí odkaz:
https://doaj.org/article/2c46fd99526543119d19069acb9f2d2a
Autor:
Phillips, Ryan S., Hidehiko Koizumi, Molkov, Yaroslav I., Rubin, Jonathan E., Smith, Jeffrey C.
Publikováno v:
eLife; 7/7/2022, p1-28, 28p
Kinetic properties of persistent Na+ current orchestrate oscillatory bursting in respiratory neurons
Publikováno v:
The Journal of General Physiology
Intrinsically oscillatory neurons in the pre-Bötzinger complex contribute to the rhythmic pattern of breathing. Yamanishi et al. show that the slow inactivation and slow recovery from inactivation exhibited by the persistent sodium current are impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c457c85e53d300f0d1d88dad1507dd
https://doi.org/10.1085/jgp.201812100
https://doi.org/10.1085/jgp.201812100
Autor:
Shigefumi Yokota, Kiyoshi Kawakami, Yoshitaka Oku, Makito Iizuka, Hiroshi Onimaru, Yasumasa Okada, Hidehiko Koizumi, Naohiro Koshiya, Keiko Ikeda
Publikováno v:
The Journal of Physiological Sciences
Respiratory activities are produced by medullary respiratory rhythm generators and are modulated from various sites in the lower brainstem, and which are then output as motor activities through premotor efferent networks in the brainstem and spinal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376e1f1387a6cf9488f7f2c807bbb1ba
http://ir.lib.shimane-u.ac.jp/53444
http://ir.lib.shimane-u.ac.jp/53444
Publikováno v:
eLife, Vol 8 (2019)
An autorhythmic population of excitatory neurons in the brainstem pre-Bötzinger complex is a critical component of the mammalian respiratory oscillator. Two intrinsic neuronal biophysical mechanisms—a persistent sodium current (INaP) and a calcium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95f2c2d3ad468449ac20e3c2d7140a8
https://doi.org/10.1101/415190
https://doi.org/10.1101/415190
Autor:
Jeffrey C. Smith, Hidehiko Koizumi, Naohiro Koshiya, Joseph Nugent, Fang Cao, Ruli Zhang, Justine X. Chia
Publikováno v:
The Journal of Neuroscience. 33:2994-3009
We comparatively analyzed cellular and circuit properties of identified rhythmic excitatory and inhibitory interneurons within respiratory microcircuits of the neonatal rodent pre-Bötzinger complex (pre-BötC), the structure generating inspiratory r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f822158ec1527ff720158a7886a5000
https://doi.org/10.1523/jneurosci.4427-12.2013
https://doi.org/10.1523/jneurosci.4427-12.2013
Autor:
Yaroslav I. Molkov, Bryan Mosher, Mohammad F. Tariq, Hidehiko Koizumi, Naohiro Koshiya, Ruli Zhang, Ilya A. Rybak, Jeffrey C. Smith, Vitaliy Marchenko, Tatiana Bezdudnaya
Publikováno v:
eNeuro
Visual Abstract
The pre-Bötzinger (pre-BötC) and Bötzinger (BötC) complexes are the brainstem compartments containing interneurons considered to be critically involved in generating respiratory rhythm and motor pattern in mammals.
The p
The pre-Bötzinger (pre-BötC) and Bötzinger (BötC) complexes are the brainstem compartments containing interneurons considered to be critically involved in generating respiratory rhythm and motor pattern in mammals.
The p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ed719fd17fa62e45386534f811f424
https://pubmed.ncbi.nlm.nih.gov/27200412
https://pubmed.ncbi.nlm.nih.gov/27200412