Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Hideharu Fukao"'
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 71:84-90
Antithrombotic activities of odorless garlic powder were demonstrated in blood fibrinolytic and coagulation systems. Though the odorless garlic preparation did not influence tissue-type plasminogen activator (t-PA) or its inhibitor secretions from hu
Publikováno v:
Thrombosis Research. 113:41-49
The growth rate of vascular smooth muscle cells (VSMCs), which were derived from aorta of mice deficient in the fibrinolytic factors tissue-type plasminogen activator (t-PA(-/-)), urokinase (u-PA(-/-)), u-PA receptor (u-PAR(-/-)) and type 1 plasminog
Publikováno v:
Pathophysiology. 9:103-109
The effect of deep sea water on the fibrinolytic properties of human vascular endothelial cells was investigated. There was no difference in the growth ratio between human umbilical vein endothelial cells (HUVECs) cultured with growth medium (RPMI-16
Publikováno v:
Life Sciences. 66:2473-2487
We previously demonstrated that tissue-type plasminogen activator (t-PA) specifically bound to its receptor (t-PAR) on human umbilical vein endothelial cells (HUVEC). In addition to analyses of t-PA binding to plasminogen activator inhibitor-1 (PAI-1
Publikováno v:
Pathophysiology. 6:217-224
We investigated the involvement of fibrinolytic system in the process of wound healing as well as angiogenesis in rats using a model system, in which polystyrene capsules with 100 perforated pores filled without (empty capsule) or with fibrin gel (fi
Autor:
Kiyotaka Okada, Osamu Matsuo, Taku Mizuno, Masayuki Yasutomi, Nobuya Tanaka, Hideharu Fukao, Sigeru Uesima
Publikováno v:
Pathophysiology. 5:99-104
The invasion and metastasis of carcinoma cells require the action of tumor-associated proteases and their inhibitors, which may also may be involved in the stages of carcinogenesis. In the present study, we evaluated the levels of fibrinolytic factor
Autor:
Osamu Matsuo, Hideharu Fukao
Publikováno v:
Seminars in Thrombosis and Hemostasis. 24:269-273
Vascular endothelial cells regulate the fibrinolytic system in blood by expressing cell-surface receptors for plasminogen and plasminogen activators (PAs) as well as secreting PAs and their inhibitors. Although several receptors for plasminogen and P
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1356(1):111-120
We demonstrated previously that tissue-type plasminogen activator (t-PA) bound to its specific receptor (t-PAR) on human umbilical vein endothelial cells (HUVEC) in suspension and that t-PAR of mol wt. 20 kDa interacted only with t-PA to form 90 kDa
Autor:
Hideharu Fukao, Tomoaki Takaishi, Haruyuki Yuasa, Osamu Matsuo, Kiyotaka Okada, Shigeru Ueshima
Publikováno v:
American Journal of Hematology. 53:151-157
Staphylokinase obtains plasminogen activating activity by forming a complex with plasminogen. Although the enzymatic activity of staphylokinase is enhanced by fibrin, how fibrin enhances enzymatic activity has not been determined yet. The effects of
Publikováno v:
Life Sciences. 59:85-96
Human endothelial cells express antithrombotic properties by producing prostacyclin, heparan sulphate and plasminogen activator (PA). Bacterial extract, such as lipopolysaccharide (LPS), damaged the blood vessels and destroyed the balance between the