Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Hidefumi, FUKUMITSU"'
Autor:
Hidefumi Fukumitsu, Hitomi Soumiya, Kaito Nakamura, Kosuke Nagashima, Makoto Yamada, Hiroyuki Kobayashi, Takahiro Miwa, Atsuki Tsunoda, Tomoko Takeda-Kawaguchi, Ken-ichi Tezuka, Shoei Furukawa
Publikováno v:
Cell Transplantation, Vol 33 (2024)
In recent years, the interest in cell transplantation therapy using human dental pulp cells (DPCs) has been increasing. However, significant differences exist in the individual cellular characteristics of human DPC clones and in their therapeutic eff
Externí odkaz:
https://doaj.org/article/5696ca13742e4e12b3402bc340858d5d
Autor:
Hiroyasu Murasawa, Hiroyuki Kobayashi, Jun Imai, Takahiko Nagase, Hitomi Soumiya, Hidefumi Fukumitsu
Publikováno v:
PLoS ONE, Vol 16, Iss 10 (2021)
Rett syndrome (RTT) is a neurodevelopmental disorder with X-linked dominant inheritance caused mainly by mutations in the methyl-CpG-binding protein 2 (MECP2) gene. The effects of various Mecp2 mutations have been extensively assessed in mouse models
Externí odkaz:
https://doaj.org/article/b8d2ef6c2414461c99a50d51293eafe9
Publikováno v:
Journal of Functional Foods, Vol 5, Iss 2, Pp 601-606 (2013)
Antidepressant-like effects of medium-chain fatty acid-containing dietary oil were examined by using mice forced to swim. This stress loading induced features typical for depression such as depressive symptoms and decreased the ratio of phosphorylate
Externí odkaz:
https://doaj.org/article/0d8e9f8f81c04294b741b8bf57edcac7
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158583 (2016)
Abnormalities in tactile perception, such as sensory defensiveness, are common features in autism spectrum disorder (ASD). While not a diagnostic criterion for ASD, deficits in tactile perception contribute to the observed lack of social communicatio
Externí odkaz:
https://doaj.org/article/17ac154fdbb54802be4e4fef1ae56e52
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 10, Pp 13484-13500 (2012)
The spinal cord of a 7-week-old female Wistar rat was hemi-transected at thoracic position 10 with a razor blade, and changes in glial cell line-derived neurotrophic factor (GDNF) protein and mRNA expression levels in the spinal cord were examined. G
Externí odkaz:
https://doaj.org/article/8ba1341e1bae4fccaad63d05d6c26b5c
Autor:
Toru Iwama, Shinichi Yoshimura, Hitomi Soumiya, Hidefumi Fukumitsu, Yoshitaka Tanaka, Shoei Furukawa
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 4, Pp 4968-4981 (2012)
In our previous study, we found that trans-2-decenoic acid ethyl ester (DAEE), a derivative of a medium-chain fatty acid, elicits neurotrophin-like signals including the activation of extracellular signal-regulated kinases 1 and 2 (ERK1/2) in culture
Externí odkaz:
https://doaj.org/article/c5d4941c18974f2699a189e2ade7ec16
Publikováno v:
Biomedical Research. 40:179-188
Single prenatal exposure to valproic acid (VPA) in rodents is a widely used preclinical model of autism spectrum disorder (ASD). Continuous prenatal VPA exposure has been recently proposed as a new ASD model that closely captures the neuropathologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e291fd53db8a153057cd7e90ea4e5f04
https://doi.org/10.2220/biomedres.40.179
https://doi.org/10.2220/biomedres.40.179
Autor:
Hitomi Aoki, Takahiro Miwa, Ken Sugiyama, Takahiro Kunisada, Toshiyuki Shibata, Yuta Shimizu, Kosuke Nagashima, Hidefumi Fukumitsu, Ken-ichi Tezuka, Kazuki Iida, Naritaka Tamaoki, Tomoko Kawaguchi, Chikara Abe, Hironobu Morita, Daijiro Hatakeyama
Publikováno v:
Journal of Bone and Mineral Metabolism. 37:467-474
The central nervous system in adult mammals does not heal spontaneously after spinal cord injury (SCI). However, SCI treatment has been improved recently following the development of cell transplantation therapy. We recently reported that fibroblast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b65295c2aad1888be8e81eb1a334fc
https://doi.org/10.1007/s00774-018-0954-8
https://doi.org/10.1007/s00774-018-0954-8
Autor:
Hitomi Soumiya, Takahiro Miwa, Naritaka Tamaoki, Ken-ichi Tezuka, Takahiro Kunisada, Kei Miyamoto, Tomoko Takeda-Kawaguchi, Takatoshi Ohno, Toshiyuki Shibata, Shoei Furukawa, Daisuke Ushiro, Hidefumi Fukumitsu, Masatake Osawa, Yumi Sato, Kosuke Nagashima, Saho Ishiguro
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
Human dental pulp cells (DPCs), adherent cells derived from dental pulp tissues, are potential tools for cell transplantation therapy. However, little work has been done to optimize such transplantation. In this study, DPCs were treated with fibrobla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e08c55fdbcd69a74c77e10880427a0
http://link.springer.com/article/10.1038/s41598-017-13373-5
http://link.springer.com/article/10.1038/s41598-017-13373-5
Cell Transplantation to the Brain with Microglia Labeled by Neuropathogenic Retroviral Vector System
Publikováno v:
Cell Transplantation, Vol 11 (2002)
A8 virus (A8-V) is a molecular clone of the neuropathogenic FrC6 virus derived from the Friend murine leukemia virus (F-MuLV). The A8-V infects endothelia and microglia in the brain. We constructed a gene transfer system with the A8-V gene. Pseudotyp
Externí odkaz:
https://doaj.org/article/7bd463dc8f5641fc92eb3853093fd41c