Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Hideaki Wakamatsu"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 1595-1618 (2018)
To synthesize nucleoside and oligosaccharide derivatives, we often use a glycosylation reaction to form a glycoside bond. Coupling reactions between a nucleobase and a sugar donor in the former case, and the reaction between an acceptor and a sugar d
Externí odkaz:
https://doaj.org/article/53296d15fdc24051a71c2038a2dea7c3
Publikováno v:
Molecules, Vol 18, Iss 1, Pp 1162-1173 (2013)
Synthesis of beneficial protected meso-DAP 9 by cross metathesis of the Garner aldehyde-derived vinyl glycine 1b with protected allyl glycine 2 in the presence of Grubbs second-generation catalyst was performed. Preparation of lipophilic N-acyl iE-DA
Externí odkaz:
https://doaj.org/article/edbffe903a7e4bd18819c14c29874c55
Publikováno v:
ARKIVOC, Vol 2011, Iss 4, Pp 104-114 (2011)
Externí odkaz:
https://doaj.org/article/5aaf0e7ec2974667aa595e6c5a8da80e
Autor:
Noriko Saito-Tarashima, Yuichi Yoshimura, Hideaki Wakamatsu, Noriaki Minakawa, Rion Maeda, Yoshihiro Natori
Publikováno v:
Organic Letters. 23:4062-4066
To develop a new nucleoside analogue applicable to oligonucleotide therapeutics, we designed a 4'-thio analogue of an LNA/BNA monomer. Synthesis of 4'-hydroxymethyl-4'-thioribonucleoside was achieved by a tandem ring-contraction-aldol reaction of a 5
Autor:
Youhei Kikuchi, Ayano Takahashi, Yuichi Yoshimura, Madoka Sasaki, Yukako Saito, Yoshihiro Natori, Ayaka Ishii, Hideaki Wakamatsu
Publikováno v:
Organic Letters. 22:5299-5303
A palladium-catalyzed regioselective three-component coupling of ynamides was developed. The reaction proceeded smoothly to furnish the desired products when carried out at 70 °C in acetonitrile/water with potassium carbonate in the presence of 2.5
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 39:365-383
To develop a novel asymmetric organocatalyst based on a ribonucleoside skeleton, we designed and synthesized 2'-aminouridine derivatives. The synthesized 2'-aminouridines having bulky substituents at both base and sugar moieties could catalyze the Di
Autor:
Hiroki Takahata, Isao Adachi, Atsushi Kato, Yoshihiro Natori, Toshihiro Sakuma, Hideaki Wakamatsu, Yuichi Yoshimura, Haruka Watanabe
Publikováno v:
Tetrahedron. 75:2866-2876
We achieved synthesis of seven stereoisomers of 1-C-n-butyl-L-iminofuranose derivatives using catalytic asymmetric alkylation and Negishi coupling as key reactions. The synthetic strategy based on these key reactions was quite useful, since both α-
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 1595-1618 (2018)
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 1595-1618 (2018)
To synthesize nucleoside and oligosaccharide derivatives, we often use a glycosylation reaction to form a glycoside bond. Coupling reactions between a nucleobase and a sugar donor in the former case, and the reaction between an acceptor and a sugar d
Publikováno v:
Synthesis. 50:3467-3486
Ring-closing metathesis (RCM) of ynamides, having alkene substituents of various lengths on the side chain, was demonstrated using the second-generation Grubbs catalyst. When the reaction of ene-ynamides was carried out in the presence of 5 mol% of t
Autor:
Rika Yanagisawa, Yuichi Yoshimura, Hideaki Wakamatsu, Nao Osawa, Yoshihiro Natori, Sho Kimura
Publikováno v:
Synlett. 28:2135-2138
Palladium-catalyzed hydroarylation of ynamides has been developed. The desired coupling products were obtained in good yields and with high regioselectivities. Various aryl iodides can be used in this reaction, permitting the syntheses of many differ