Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hideaki Nakahara"'
Autor:
Susumu Watanuki, Naoki Imanishi, Yoko Yamagiwa, Mitsuaki Ohta, Toshiyasu Mase, Keiji Miyata, Takeshi Suzuki, Hideaki Nakahara, Hirotsune Itahana
Publikováno v:
Chemical and Pharmaceutical Bulletin. 46:1116-1124
A novel series of 4-amino-N-[2-(1-aminocycloalkan-1-yl)ethyl]-5-chloro-2-methoxyb enzamides. derivatives (1), which had amines conformationally restricted due to the effect of repulsion by neighboring substituents, were prepared and evaluated for 5-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1126f443d9c17971b5ebeb7d4b5bd280
https://doi.org/10.1248/cpb.46.1116
https://doi.org/10.1248/cpb.46.1116
Autor:
Hiroyuki Kurihara, Kousei Kawamuki, Makoto Takeuchi, Yasuo Isomura, Hideaki Nakahara, Shunichi Sakamoto
Publikováno v:
Chemical and Pharmaceutical Bulletin. 46:1703-1709
Two new series of fused aza-heteroarylbisphosphonates (5, 8), which are structurally quite different from incadronate (YM175), and related compounds were synthesized and evaluated for antiresorptive activity using a parathyroid hormone (PTH)-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e36dc6845f6d2f1d5fd0c99ee2500b72
https://doi.org/10.1248/cpb.46.1703
https://doi.org/10.1248/cpb.46.1703
Publikováno v:
ChemInform. 22
Platinum adducts obtained from the reaction of 3′-O,5′-O-phosphodiguanosine, r(GpG), with the asymmetric complexes cis-[PtCl2L(L′)](L = NH3; L′= alkylamine such as NH2Me, NH2Et, NHMe2and NHEt2; LL′=N,N-dimethylethylenediamine) have been str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df56376dace2c2687f63652dfa5bc4bb
https://doi.org/10.1002/chin.199133245
https://doi.org/10.1002/chin.199133245
Autor:
Takeshi Suzuki, Yoko Yamagiwa, Hirotsune Itahana, Hideaki Nakahara, Toshiyasu Mase, Susumu Watanuki, Naoki Imanishi, Mitsuaki Ohta, Keiji Miyata
Publikováno v:
ChemInform. 29
A novel series of 4-amino-N-[2-(1-aminocycloalkan-1-yl)ethyl]-5-chloro-2-methoxyb enzamides. derivatives (1), which had amines conformationally restricted due to the effect of repulsion by neighboring substituents, were prepared and evaluated for 5-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eed2378cd1b9a0bf5f2dd62b74a24b2
https://doi.org/10.1002/chin.199852109
https://doi.org/10.1002/chin.199852109
Autor:
Makoto Takeuchi, Shuichi Sakamoto, Hideaki Nakahara, Yasuo Isomura, Kousei Kawamuki, Hiroyuki Kurihara
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c01ee7145e96db100a15db684f68187f
https://doi.org/10.1002/chin.199921175
https://doi.org/10.1002/chin.199921175
Autor:
Naoki Imanishi, Takeshi Suzuki, Kiyoshi Iwaoka, Toshiyasu Mase, Mitsuaki Ohta, Keiji Miyata, Yukinori Nagakura, Hideaki Nakahara
Publikováno v:
ChemInform. 30
Serotonin (5-hydroxytryptamine, 5-HT) is widely distributed in the central nervous, gastrointestinal, and cardiovascular systems as a neurotransmitter, neuromodulator and hormone. 1—6) The 5-hydroxytryptamine 4 (5-HT4) receptor is distributed from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b80f2bc09d8342142f37b8b02496976
https://doi.org/10.1002/chin.199930150
https://doi.org/10.1002/chin.199930150
Autor:
Yuzo Matsumoto, Wataru Uchida, Hideaki Nakahara, Isao Yanagisawa, Tadao Shibanuma, Hiroyuki Nohira
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f440cfffdb092bdd6da46e7fa5debfa
https://doi.org/10.1002/chin.200032132
https://doi.org/10.1002/chin.200032132
Publikováno v:
Inorganic Chemistry. 29:4496-4500
Diastereoisomers obtained from the reaction of d(GpG) with the three isomers of Pt(1,2-cyclohexanediamine) 2+ have been investigated by means of high-resolution 1 H NMR spectroscopy. The reaction of d(GpG) with each Pt(R,R/S,S/R,S-dach) 2+ gave a G-N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d4580dd5735a75e651c6ba581db79c8
https://doi.org/10.1021/ic00347a032
https://doi.org/10.1021/ic00347a032
Autor:
Masaya Orita, Tomoyuki Yokota, Hiroshi Suzuki, Toru Kontani, Hironobu Koga, Masao Matsuoka, Ayako Moritomo, Kenji Sudo, Tetsuro Ohgami, Hideaki Nakahara, Masahiro Fujii, Shunji Kageyama, Osamu Yamamoto, Masanori Baba, Yasuaki Shimizu, Naoyuki Masuda, Hiroyuki Kurihara, Hiroshi Inoue, Jiro Fujiyasu, Toshifumi Hatta, Eiichi Kodama, Masatoshi Fujiwara, Mitsuaki Ohta, Shiro Shigeta
Publikováno v:
Bioorganicmedicinal chemistry. 12(23)
A random high-throughput screening (HTS) program to discover novel nonnucleoside reverse transcriptase inhibitors (NNRTIs) has been carried out with MT-4 cells against a nevirapine-resistant virus, HIV-1 IIIB-R . The primary hit, a thiazolidenebenzen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5a3e3e21460517253c918a4ab93d07
https://pubmed.ncbi.nlm.nih.gov/15519161
https://pubmed.ncbi.nlm.nih.gov/15519161
Autor:
Hideaki Nakahara, Susumu Watanuki, Masanao Sanagi, Masaya Orita, Akihiro Tanaka, Katsumi Sudoh, Shin-ichi Tsukamoto, Ryuji Tsuzuki, Jun-Ichi Kazami, Akira Fujimori, Hironori Harada, Isao Yanagisawa, Jun Shimaya
Publikováno v:
Bioorganicmedicinal chemistry. 9(11)
In the previous paper, we described a series of 2-phenylethenesulfonamide derivatives, a novel class of ET(A)-selective endothelin (ET) receptor antagonists, including the 2-methoxyethoxy derivative 2a and the 2-fluoroethoxy derivative (2b). In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fccc8c06fe302efd516309b6026de6d1
https://pubmed.ncbi.nlm.nih.gov/11597477
https://pubmed.ncbi.nlm.nih.gov/11597477