Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Hideaki Matsushita"'
Autor:
Hideaki Matsushita, Masanori Hijioka, Akinori Hisatsune, Yoichiro Isohama, Shigeto Iwamoto, Hiroaki Terasawa, Hiroshi Katsuki
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67691 (2013)
Intracerebral hemorrhage (ICH) is featured by poor prognosis such as high mortality rate and severe neurological dysfunction. In humans, several valuables including hematoma volume and ventricular expansion of hemorrhage are known to correlate with t
Externí odkaz:
https://doaj.org/article/48efc3402e1c46bfa37b645b5f98a2bf
Autor:
Hayato Ishibashi, Yuki Kurauchi, Masanori Hijioka, Junpei Anan, Hideaki Matsushita, Takahiro Seki, Hiroshi Katsuki, Akinori Hisatsune
Publikováno v:
Neuroscience Research. 106:38-46
Previously we showed that expansion of intracerebral hemorrhage (ICH) into the internal capsule greatly aggravated neurological symptoms in mice. Here we examined ICH-associated events in the internal capsule with relation to neurological dysfunction
Autor:
Hideaki Matsushita, Yuki Kurauchi, Koichi Shudo, Akinori Hisatsune, Junpei Anan, Hiroshi Katsuki, Takahiro Seki, Hayato Ishibashi, Masanori Hijioka
Publikováno v:
Journal of Neuroscience Research. 92:1024-1034
We previously demonstrated that a synthetic retinoic acid receptor agonist, Am80, attenuated intracerebral hemorrhage (ICH)-induced neuropathological changes and neurological dysfunction. Because inflammatory events are among the prominent features o
Autor:
Hayato Ishibashi, Masanori Hijioka, Hiroshi Katsuki, Hideaki Matsushita, Akinori Hisatsune, Yoichiro Isohama
Publikováno v:
Neuroscience. 222:10-19
We have demonstrated previously that nicotine affords neuroprotective and anti-inflammatory effects against intracerebral hemorrhage (ICH)-associated neuropathological changes. The present study was undertaken to clarify whether subtype-specific agon
Autor:
Yoichiro Isohama, Hideaki Matsushita, Koichi Shudo, Hiroshi Katsuki, Akinori Hisatsune, Masanori Hijioka
Publikováno v:
European Journal of Pharmacology. 683:125-131
We have recently proposed that retinoic acid receptor (NR1B) is a promising target of neuroprotective therapy for intracerebral hemorrhage, since pretreatment of mice with an NR1B1/NR1B2 agonist Am80 attenuated various pathological and neurological a
Autor:
Yoichiro Isohama, Hiroshi Katsuki, Hideaki Matsushita, Koichi Shudo, Akinori Hisatsune, Masanori Hijioka
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 31:222-234
Am80 (tamibarotene) is a retinoic acid receptor (RAR) agonist clinically available for treatment of acute promyelocytic leukemia. As intracerebral hemorrhage (ICH) accompanies inflammatory reactions in the brain and also because retinoids may suppres
Autor:
Hideaki, Matsushita, Masanori, Hijioka, Hayato, Ishibashi, Junpei, Anan, Yuki, Kurauchi, Akinori, Hisatsune, Takahiro, Seki, Koichi, Shudo, Hiroshi, Katsuki
Publikováno v:
Journal of neuroscience research. 92(8)
We previously demonstrated that a synthetic retinoic acid receptor agonist, Am80, attenuated intracerebral hemorrhage (ICH)-induced neuropathological changes and neurological dysfunction. Because inflammatory events are among the prominent features o
Autor:
Yoichiro Isohama, Hiroaki Terasawa, Hideaki Matsushita, Masanori Hijioka, Shigeto Iwamoto, Akinori Hisatsune, Hiroshi Katsuki
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67691 (2013)
PLoS ONE
PLoS ONE
Intracerebral hemorrhage (ICH) is featured by poor prognosis such as high mortality rate and severe neurological dysfunction. In humans, several valuables including hematoma volume and ventricular expansion of hemorrhage are known to correlate with t
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 338(3)
Intracerebral hemorrhage (ICH) resulting from the leakage of blood into the brain parenchyma triggers severe tissue damage involving neurodegeneration and inflammation. Increasing lines of evidence indicate that the stimulation of central nicotinic a
Autor:
Akinori Hisatsune, Tetsuhiro Uematsu, Masanori Hijioka, Sigeto Iwamoto, Hiroshi Katsuki, Hiroaki Terasawa, Hideaki Matsushita, Yoichiro Isohama
Publikováno v:
Neuroscience Research. 71:e406
4-t14 MRI-based examinations of mouse brain after ntracerebral hemorrhage reveal relationship of hemorhage expansion with mortality rate and sensorimotor ysfunctions ideaki Matsushita1 , Masanori Hijioka1, Tetsuhiro Uematsu1, kinori Hisatsune1, Yoich