Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Hideaki Ichiba"'
Autor:
Mayu Onozato, Yukina Okanishi, Misumi Akutsu, Ikumi Okumura, Aina Nemoto, Kyosuke Takano, Tatsuya Sakamoto, Hideaki Ichiba, Takeshi Fukushima
Publikováno v:
Practical Laboratory Medicine, Vol 18, Iss , Pp - (2020)
Objectives: Ethyl icosapentate, a prodrug of eicosapentaenoic acid (EPA), has been prescribed to not only hyperlipidemia, but also psychotic patients. We have examined the impact of an orally administered polyunsaturated fatty acid (PUFA), ethyl icos
Externí odkaz:
https://doaj.org/article/732aa93e274c4b8aac600a00348cf02c
Autor:
Shusuke Uekusa, Mayu Onozato, Tatsuya Sakamoto, Maho Umino, Hideaki Ichiba, Kenji Okoshi, Takeshi Fukushima
Publikováno v:
Molecules, Vol 26, Iss 12, p 3498 (2021)
Taurine (Tau) has some important ameliorating effects on human health and is present in bivalve. For the selective analysis of Tau with other amino acids, we designed a derivatization reagent, 2,5-dioxopyrrolidin-1-yl(4-(((2-nitrophenyl)sulfonyl)oxy)
Externí odkaz:
https://doaj.org/article/c66bcfc72ce64bcf8ac03503f4305fb9
Autor:
Mayu Onozato, Yuriko Tanaka, Michitsune Arita, Tatsuya Sakamoto, Hideaki Ichiba, Kiyomi Sadamoto, Motonari Kondo, Takeshi Fukushima
Publikováno v:
Practical Laboratory Medicine, Vol 12, Iss , Pp - (2018)
Objectives: Amino acid levels in serum or plasma are used for early detection and diagnosis of several diseases. The objective of this study was to analyze amino acid levels in serum exosomes, which have not been previously reported. Design and metho
Externí odkaz:
https://doaj.org/article/e2a5f77dbf834503971396e368935ee4
Autor:
Mayu Onozato, Hiromi Nakazawa, Katsuyuki Ishimaru, Chihiro Nagashima, Minori Fukumoto, Hitomi Hakariya, Tatsuya Sakamoto, Hideaki Ichiba, Takeshi Fukushima
Publikováno v:
Heliyon, Vol 3, Iss 9 (2017)
Aims: d-Serine (d-Ser), a co-agonist of N-methyl-d-aspartate receptor (NMDAR), is effective for treating schizophrenia. The present study investigated changes in plasma and striatal d-Ser levels in Sprague-Dawley (SD) rats after intraperitoneal d-Ser
Externí odkaz:
https://doaj.org/article/d5f7c99924604d0da0524c4def962def
Autor:
Takeshi Fukushima, Hideaki Iizuka, Ayaka Yokota, Takehiro Suzuki, Chihiro Ohno, Yumiko Kono, Minami Nishikiori, Ayaka Seki, Hideaki Ichiba, Yoshinori Watanabe, Seiji Hongo, Mamoru Utsunomiya, Masaki Nakatani, Kiyomi Sadamoto, Takashi Yoshio
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101652 (2014)
The serum levels of several metabolites are significantly altered in schizophrenia patients. In this study, we performed a targeted analysis of 34 candidate metabolites in schizophrenia patients (n = 25) and compared them with those in age- and gende
Externí odkaz:
https://doaj.org/article/15c59259304442638aa1af0a7487615a
Publikováno v:
Journal of Chromatographic Science. 58:636-640
It has been suggested that thiol-containing amino acids could be used as biomarkers for diseases associated with oxidative stress. We investigated the thiol-containing amino acids, homocysteine (Hcy), cysteine (Cys), glutathione (GSH) and γ-glutamyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64606c2a2744d351f656318c612cb986
https://doi.org/10.1093/chromsci/bmaa028
https://doi.org/10.1093/chromsci/bmaa028
Autor:
Maho Umino, Takeshi Fukushima, Shusuke Uekusa, Mika Shirao, Tatsuya Sakamoto, Mayu Onozato, Hideaki Ichiba
Publikováno v:
Journal of chromatography. A. 1652
We designed and synthesized three novel derivatization reagents bearing chiral 4-imidazolidinone, namely succinimidyl 2-(3-((benzyloxy)carbonyl)-1-methyl, ethyl, and -phenyl-5-oxoimidazolidin-4-yl)acetates (CIMs), for use in liquid chromatography-tan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f903fc9241e1fec0fe96e384c4f968
https://pubmed.ncbi.nlm.nih.gov/34192611
https://pubmed.ncbi.nlm.nih.gov/34192611
Autor:
Maho Umino, Mayu Onozato, Shusuke Uekusa, Takeshi Fukushima, Tatsuya Sakamoto, Hideaki Ichiba
Publikováno v:
Biomedical chromatography : BMCREFERENCES. 35(5)
Herein, determination of an anti-epileptic drug, (±)-vigabatrin (VB), was performed by reversed-phase HPLC with fluorimetric detection using a newly designed and synthesised fluorescence derivatisation reagent, 2,5-dioxopyrrolidin-1-yl (4-(((2-nitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c4051929f173b0ba4b0c8ae0889fce
https://pubmed.ncbi.nlm.nih.gov/33377241
https://pubmed.ncbi.nlm.nih.gov/33377241
Autor:
Mayu Onozato, Shusuke Uekusa, Takeshi Fukushima, Maho Umino, Tatsuya Sakamoto, Hideaki Ichiba
Publikováno v:
Journal of Chromatography B. 1179:122866
Mixed-mode chromatography—comprising a mixed phase with reversed and ionic phases, enabling hydrophobic and ion-exchange interactions simultaneously—was applied to identify vigabatrin enantiomers by HPLC with pre-column fluorescence derivatizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317b78b53d006acd98f8b920769b19fe
https://doi.org/10.1016/j.jchromb.2021.122866
https://doi.org/10.1016/j.jchromb.2021.122866
Autor:
Hideaki Ichiba, Naomi Fukuoka, Masafumi Mizuno, Takeshi Fukushima, Naohisa Tsujino, Ayaka Magarida, Takahiro Nemoto, Tomoyuki Funatogawa, Mayu Onozato, Arisa Uta, Hiromi Tagata
Publikováno v:
Clinical biochemistry. 77
Background Disturbance of the methionine (Met) cycle, which produces Met from homocysteine (Hcy), is suggested to be involved in several diseases, including psychiatric disorders. This study was aimed to investigate both levels of Met and Hcy in seru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4dd2f25efae54b9c0afe40b8156c33
https://pubmed.ncbi.nlm.nih.gov/31843665
https://pubmed.ncbi.nlm.nih.gov/31843665