Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hideaki Asahara"'
Autor:
Satoshi O. Suzuki, Jun Ichi Kira, Koji Shinoda, Toru Iwaki, Taira Uehara, Katsue Miyoshi, Hideaki Asahara
Publikováno v:
Multiple Sclerosis Journal. 21:252-254
We report the first case of an occurrence of multiphasic acute disseminated encephalomyelitis (ADEM) associated with atypical rubella virus infection with no rash and long-term increased titers of serum anti-rubella IgM in a 17-year-old male who had
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70fc6f34f95ac93e4c4205d7e25ee9ae
https://doi.org/10.1177/1352458514533845
https://doi.org/10.1177/1352458514533845
Autor:
Ying-Hui Fu, Quasar S Padiath, Takeshi Yamada, Kirk J. Hogan, Anulf Koeppen, Hideaki Asahara, Raphael Schiffmann, Kazumasa Saigoh, Louis J. Ptáček
Publikováno v:
Nature Genetics. 38:1114-1123
Adult-onset autosomal dominant leukodystrophy (ADLD) is a slowly progressive neurological disorder characterized by symmetrical widespread myelin loss in the central nervous system, with a phenotype similar to chronic progressive multiple sclerosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abbaf12ced56c9eded2beb7507da7296
https://doi.org/10.1038/ng1872
https://doi.org/10.1038/ng1872
Autor:
Kazuya Takeda, Takayuki Taniwaki, Nobutaka Sakae, Frédéric Checler, Takeshi Yamada, Yasumasa Ohyagi, Takeshi Tabira, Takao Makifuchi, Takeshi Kawarabayashi, Hiroyuki Murai, Hitoshi Kikuchi, Katsue Miyoshi, Hideaki Asahara, Jun Ichi Kira, Toru Iwaki, Mikio Shoji, Yuko Tsuruta, Koji Ikezoe, De Hua Chui, Hirokazu Furuya
Publikováno v:
The FASEB Journal. 19:1-29
The amyloid beta-protein (Abeta) ending at 42 plays a pivotal role in Alzheimer's disease (AD). We have reported previously that intracellular Abeta42 is associated with neuronal apoptosis in vitro and in vivo. Here, we show that intracellular Abeta4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d810e83a070bb48338dab331c14f0e
https://doi.org/10.1096/fj.04-2637fje
https://doi.org/10.1096/fj.04-2637fje
Autor:
Yasumasa Ohyagi, Izumi Horiuchi, Kimihiro Tanaka, Jun Ichi Kira, Hideaki Asahara, Takeshi Yamada
Publikováno v:
Journal of the Neurological Sciences. 183:79-84
Familial amyloidotic polyneuropathy type 1 (FAP) is an autosomal-dominantly inherited disorder with systemic deposition of a variant transthyretin (TTR). We attempted to suppress TTR production by ribozyme degradation of TTR mRNA. Hammerhead and hair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b24320e196e9e234e071d359650c4a
https://doi.org/10.1016/s0022-510x(00)00481-0
https://doi.org/10.1016/s0022-510x(00)00481-0
Autor:
Yasumasa Ohyagi, Takayuki Taniwaki, T. Yamada, Izumi Horiuchi, Nobue Shinnoh, Jun Ichi Kira, Hideaki Asahara
Publikováno v:
Journal of Inherited Metabolic Disease. 23:607-614
Lovastatin, an inhibitor of 3-hydroxy-3-methylglutarylcoenzyme A reductase, normalizes the very long-chain fatty acids (VLCFA) concentrations in fibroblasts and plasma from patients with X-linked adrenoleukodystrophy (X-ALD). The effects of lovastati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f5d6a7acc9813e07b1f943894fa65c
https://doi.org/10.1023/a:1005634130286
https://doi.org/10.1023/a:1005634130286
Publikováno v:
Neurochemical Research. 24:685-690
A recent study revealed that ceramide acts as a second messenger in the sphingomyelin pathway and thus plays an important regulatory role in programmed cell death (apoptosis) to cell the lines induced by tumor-necrosis factor (TNF)-α and interleukin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::202ceaf307fe4c7df7f0d3c4750759d2
https://doi.org/10.1023/a:1021008626887
https://doi.org/10.1023/a:1021008626887
Autor:
Linda H. Younkin, Maria Hella, James Ronald, Leah Scanlin, Yasumasa Ohyagi, Mariza de Andrade, Eugene Gnida, Ronald C. Petersen, Nilufer Ertekin-Taner, Daniel J. Fadale, Samuel Younkin, Shushant Jain, Adam Singleton, Neill R. Graff-Radford, Mike Hutton, Hideaki Asahara, Steven G. Younkin
Using plasma amyloid beta protein (Abeta42) levels as an intermediate, quantitative phenotype for late onset Alzheimer's disease (LOAD), we previously obtained significant linkage at approximately 80 cM on chromosome 10. Linkage to the same region wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9297b1cd68dc0b320a90b6d3c0537135
https://europepmc.org/articles/PMC2836540/
https://europepmc.org/articles/PMC2836540/
Publikováno v:
Journal of the neurological sciences. 171(2)
In amyotrophic lateral sclerosis (ALS), an abnormal increase of glutamate in the central nervous system indicates that it may play a key role in motor neuron death. The neuronal accumulation of phosphorylated neurofilaments (NFs) suggests an alterati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c85a9538cb667c1b4b7c03a4171cb9c
https://pubmed.ncbi.nlm.nih.gov/10581372
https://pubmed.ncbi.nlm.nih.gov/10581372
Autor:
Takeshi Yamada, Ying-Hui Fu, Anulf Koeppen, Quasar S Padiath, Raphael Schiffmann, Kirk J. Hogan, Hideaki Asahara, Louis J. Ptáček, Kazumasa Saigoh
Publikováno v:
Nature Genetics. 39:276-276
Nature Genetics 38, 1114–1123 (2006); published online 3 September; corrected online 12 September 2006; corrected after print 22 January 2007 The construct we described as moody-GAL4 has a name that was assigned to a different construct in a previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92f48051fd56378e64fb02c2ce1217a3
https://doi.org/10.1038/ng0207-276c
https://doi.org/10.1038/ng0207-276c
Autor:
Steven G. Younkin, Maria Hella, Yasumasa Ohyagi, Lars Feuk, Mariet Allen, Ronald C. Petersen, Hideaki Asahara, Linda H. Younkin, Shushant Jain, Eugene Gnida, James Ronald, Jonathan A. Prince, Adam Singleton, Leah Scanlin, Neill R. Graff-Radford, Anthony J. Brookes, Mariza de Andrade, Nilufer Ertekin-Taner, Mike Hutton, Samuel Younkin, Daniel J. Fadale, Chloe M. Stanton
Publikováno v:
Neurobiology of Aging. 25:S501
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45f9b2d9dff30cf5bc3616315c687e54
https://doi.org/10.1016/s0197-4580(04)81653-1
https://doi.org/10.1016/s0197-4580(04)81653-1