Zobrazeno 1 - 10
of 320
pro vyhledávání: '"Hideaki Oikawa"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Natural secondary metabolites are medically, agriculturally, and industrially beneficial to humans. For mass production, a heterologous production system is required, and various metabolic engineering trials have been reported in Escherichia
Externí odkaz:
https://doaj.org/article/cbef1b14c89a4c24890c3cc90ad2c7a1
Publikováno v:
Precision Chemistry, Vol 2, Iss 3, Pp 120-126 (2024)
Externí odkaz:
https://doaj.org/article/9a47f55d685b44109aa40cfaf784e09f
Autor:
Kei Hiruma, Seishiro Aoki, Junya Takino, Takeshi Higa, Yuniar Devi Utami, Akito Shiina, Masanori Okamoto, Masami Nakamura, Nanami Kawamura, Yoshihiro Ohmori, Ryohei Sugita, Keitaro Tanoi, Toyozo Sato, Hideaki Oikawa, Atsushi Minami, Wataru Iwasaki, Yusuke Saijo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Plant-associated fungi show diverse lifestyles from pathogenic to mutualistic to the host; however, the principles and mechanisms through which they shift the lifestyles require elucidation. The root fungus Colletotrichum tofieldiae (Ct) pro
Externí odkaz:
https://doaj.org/article/75fe1437b23e4bc4a90210d880c8726c
Autor:
Akari Kotani, Taro Ozaki, Junya Takino, Susumu Mochizuki, Kazuya Akimitsu, Atsushi Minami, Hideaki Oikawa
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 86:287-293
Previously, we succeeded to produce the core structure of the host-selective ACR toxin (1) on brown leaf spot on rough lemon when the polyketide synthase ACRTS2 gene was heterologously expressed in Aspergillus oryzae (AO). To confirm the production o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0885ad742445669f10809e4eb271064
https://doi.org/10.1093/bbb/zbab214
https://doi.org/10.1093/bbb/zbab214
Autor:
Chengwei Liu, Atsushi Minami, Taro Ozaki, Yuya Igarashi, Yuka Naganuma, Kaho Sogahata, Hideaki Oikawa
Publikováno v:
Angewandte chemie-international edition. 60(49):25729-25734
UstYa family proteins (DUF3328) are widely and specifically distributed in fungi. They are known to be involved in the biosynthesis of ribosomally synthesized and posttranslationally modified peptides (RiPPs) and nonribosomal peptides, and possibly c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a789f1a1f8e5eda3e74dfab55498afd
http://hdl.handle.net/2115/87349
http://hdl.handle.net/2115/87349
Autor:
Shintaro Yamamoto, Taro Matsuyama, Taro Ozaki, Junya Takino, Hajime Sato, Masanobu Uchiyama, Atsushi Minami, Hideaki Oikawa
Publikováno v:
Journal of the American Chemical Society. 144(46)
Antihypercholesterolemic agent phomoidride (PMD) B has a highly elaborated bicyclo[4.3.1]deca-1,6-diene core scaffold derived from dimeric anhydride with a nine-membered ring. This report elucidated the late stage transformation from an anhydride mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9863f8866c4dfed552d81fc84cb6f2
https://pubmed.ncbi.nlm.nih.gov/36374185
https://pubmed.ncbi.nlm.nih.gov/36374185
Publikováno v:
Natural product reports.
Covering: 2013 to 2022In this review, we provide an overview elucidating the biosynthetic pathway and heterologous production of fungal indole diterpenes (IDTs). Based on the studies of six IDT biosynthesis, we extracted nature's strategy: (1) two-st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6671d23b85f2a16073e4127d5d75b9e
https://pubmed.ncbi.nlm.nih.gov/36321441
https://pubmed.ncbi.nlm.nih.gov/36321441
Autor:
Junya Takino, Akari Kotani, Taro Ozaki, Wenquan Peng, Jie Yu, Yian Guo, Susumu Mochizuki, Kazuya Akimitsu, Masaru Hashimoto, Tao Ye, Atsushi Minami, Hideaki Oikawa
Publikováno v:
Angewandte Chemie. 133:23591-23599
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f907c3ede8174c32916ec7f940db2d31
https://doi.org/10.1002/ange.202110658
https://doi.org/10.1002/ange.202110658
Autor:
Jie Yu, Wenquan Peng, Susumu Mochizuki, Hideaki Oikawa, Taro Ozaki, Atsushi Minami, Tao Ye, Masaru Hashimoto, Junya Takino, Akari Kotani, Kazuya Akimitsu, Yian Guo
Publikováno v:
Angewandte Chemie International Edition. 60:23403-23411
Highly reducing polyketide synthases (HR-PKSs) produce structurally diverse polyketides (PKs). The PK diversity is constructed by a variety of factors, including the β-keto processing, chain length, methylation pattern, and relative and absolute con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bfb8e8b304d7772601d7dbe114ba2c3
https://doi.org/10.1002/anie.202110658
https://doi.org/10.1002/anie.202110658
Publikováno v:
The Journal of antibiotics. 76(1)
Ribosomally synthesized and posttranslationally modified peptides (RiPPs) are growing class of natural products with potent biological activities. Although the core scaffolds of RiPPs are composed of proteinogenic amino acids, remarkable structural d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7371ad15474719ef5dc82312c75b170
https://pubmed.ncbi.nlm.nih.gov/36424516
https://pubmed.ncbi.nlm.nih.gov/36424516