Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hidde Douna"'
Autor:
Hidde Douna, J. de Mol, Jacob Amersfoort, Frank H. Schaftenaar, Mate G. Kiss, Bianca E. Suur, Mara J. Kroner, Christoph J. Binder, Ilze Bot, Gijs H. M. Van Puijvelde, Johan Kuiper, Amanda C. Foks
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
B and T cells are interconnected in the T follicular helper—germinal center B cell (TFH-GC B cell) axis, which is hyperactive during atherosclerosis development and loss of control along this axis results in exacerbated atherosclerosis. Inhibition
Externí odkaz:
https://doaj.org/article/b7e329b21fe3497880611ebc48962b59
Autor:
Jacob Amersfoort, Hidde Douna, Frank H. Schaftenaar, Amanda C. Foks, Mara J. Kröner, Peter J. van Santbrink, Gijs H. M. van Puijvelde, Ilze Bot, Johan Kuiper
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Macroautophagy (or autophagy) is a conserved cellular process in which cytoplasmic cargo is targeted for lysosomal degradation. Autophagy is crucial for the functional integrity of different subsets of T cells in various developmental stages. Since a
Externí odkaz:
https://doaj.org/article/8cd87af9006544a1af0eb617c945cff4
Autor:
Hongbo Chi, Frank H. Schaftenaar, Jacob Amersfoort, Yanyan Wang, Estefanía Moreno-Gordaliza, Gijs H.M. van Puijvelde, Ilze Bot, Thomas Hankemeier, Bram Slütter, Peter J. van Santbrink, Johan Kuiper, Amy C. Harms, Hidde Douna, Amanda C. Foks
Publikováno v:
Cardiovascular research
Cardiovascular research, 117(5), 1309-1324
Cardiovascular research, 117(5), 1309-1324
Aims A hallmark of advanced atherosclerosis is inadequate immunosuppression by regulatory T (Treg) cells inside atherosclerotic lesions. Dyslipidemia has been suggested to alter Treg cell migration by affecting the expression of specific membrane pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166b657e0abc98ccb980fb131945aa2d
https://doi.org/10.1093/cvr/cvaa208
https://doi.org/10.1093/cvr/cvaa208
Autor:
Hidde Douna, Jacob Amersfoort, Gijs H.M. van Puijvelde, Ilze Bot, Jan W. Drijfhout, Johan Kuiper, Mara J. Kröner, Amanda C. Foks, Frank H. Schaftenaar, Bram Slütter
Publikováno v:
Scientific Reports, 9(1), 17391
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Cardiovascular diseases form the most common cause of death worldwide, with atherosclerosis as main etiology. Atherosclerosis is marked by cholesterol rich lipoprotein deposition in the artery wall, evoking a pathogenic immune response. Characteristi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f8e07924453ef9dd1a6ebe465a0795
http://hdl.handle.net/1887/82160
http://hdl.handle.net/1887/82160
Autor:
Mara J. Kröner, A. Wezel, Hidde Douna, Marie A.C. Depuydt, M.N.A. Bernabé Kleijn, Hideo Yagita, G.H.M. van Puijvelde, M.B. Kiss, Amanda C. Foks, Jacob Amersfoort, Harm Smeets, Johan Kuiper, Frank H. Schaftenaar, Bram Slütter, Christoph J. Binder, Ilze Bot
Publikováno v:
Cardiovascular Research, 116(2), 295-305
Cardiovascular Research
Cardiovascular Research
The immune system is strongly involved in atherosclerosis and immune regulation generally leads to attenuated atherosclerosis. B- and T-lymphocyte attenuator (BTLA) is a novel co-receptor that negatively regulates the activation of B and T cells; how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1f721475fcb96b14f1883a750dbff0
https://hdl.handle.net/1887/79796
https://hdl.handle.net/1887/79796
Autor:
Frank H. Schaftenaar, Hidde Douna, Gijs H.M. van Puijvelde, Jacob Amersfoort, Ilze Bot, Peter J. van Santbrink, Amanda C. Foks, Johan Kuiper, Mara J. Kröner
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, 9, 2937
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, 9, 2937
Frontiers in Immunology, Vol 9 (2018)
Macroautophagy (or autophagy) is a conserved cellular process in which cytoplasmic cargo is targeted for lysosomal degradation. Autophagy is crucial for the functional integrity of different subsets of T cells in various developmental stages. Since a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cdc3be080b5b0c0704a0d6adb9a34c3
https://doi.org/10.3389/fimmu.2018.02937
https://doi.org/10.3389/fimmu.2018.02937
Autor:
Gijs H.M. van Puijvelde, Amanda C. Foks, Sanne Kroon, Hidde Douna, Jacob Amersfoort, Frank H. Schaftenaar, Johan Kuiper
Background and aims Limiting the pro-inflammatory immune response is critical for the treatment of atherosclerosis. Regulatory B cells (Bregs) can modulate the immune response through interleukin-10 (IL-10). Current data regarding Bregs and atheroscl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89dcc04d2223bda182a5b7dfb8b2375d
https://doi.org/10.1016/j.atherosclerosis.2018.11.019
https://doi.org/10.1016/j.atherosclerosis.2018.11.019
Autor:
P.J. van Santbrink, Mara J. Kröner, Hidde Douna, Paul H.A. Quax, G.H.M. van Puijvelde, Johan Kuiper, Ilze Bot, Frank H. Schaftenaar, Jacob Amersfoort
Publikováno v:
Atherosclerosis, 275, 214-224
Atherosclerosis
Atherosclerosis
Lipocalin-2 (Lcn2) is a glycoprotein which can be secreted by immune cells. Several studies in humans have suggested Lcn2 can be used as a biomarker for the detection of unstable atherosclerotic lesions, partly as it is known to interact with MMP-9.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d9f8df004667cac738a6f1b15723cb
http://hdl.handle.net/1887/66066
http://hdl.handle.net/1887/66066
Autor:
Hidde, Douna, Jacob, Amersfoort, Frank H, Schaftenaar, Sanne, Kroon, Gijs H M, van Puijvelde, Johan, Kuiper, Amanda C, Foks
Publikováno v:
Atherosclerosis. 280
Limiting the pro-inflammatory immune response is critical for the treatment of atherosclerosis. Regulatory B cells (Bregs) can modulate the immune response through interleukin-10 (IL-10). Current data regarding Bregs and atherosclerosis is scarce and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65e06d60dd290b1c0a44467942691121
https://pubmed.ncbi.nlm.nih.gov/30500604
https://pubmed.ncbi.nlm.nih.gov/30500604
Autor:
Mara J. Kröner, Gijs H.M. van Puijvelde, Hidde Douna, Johan Kuiper, Bram Slütter, Jacob Amersfoort, Ilze Bot, Frank H. Schaftenaar
CD8 T cells make up a large amount of lymphocytes in atherosclerotic plaques, however their role in atherosclerosis has not been thoroughly studied. Since ApoB100 is a key antigen in atherosclerosis and a plausible vaccination target, we were interes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ccaaab90554053939410a3f15418f17
http://hdl.handle.net/1887/3203194
http://hdl.handle.net/1887/3203194