Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hidayat Lokman"'
Autor:
Weonjin Yu, Yi-Chun Yen, Young-Hwan Lee, Shawn Tan, Yixin Xiao, Hidayat Lokman, Audrey Khoo Tze Ting, Hasini Ganegala, Taejoon Kwon, Won-Kyung Ho, H. Shawn Je
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-13 (2019)
Abstract Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed antidepressant drugs in pregnant women. Infants born following prenatal exposure to SSRIs have a higher risk for behavioral abnormalities, however, the underlying mechan
Externí odkaz:
https://doaj.org/article/1e08fa7383584109bbbe2f4acd3ba97d
Autor:
Wei Zhang, Paul Jong Kim, Zhongcan Chen, Hidayat Lokman, Lifeng Qiu, Ke Zhang, Steven George Rozen, Eng King Tan, Hyunsoo Shawn Je, Li Zeng
Publikováno v:
eLife, Vol 5 (2016)
During the development, tight regulation of the expansion of neural progenitor cells (NPCs) and their differentiation into neurons is crucial for normal cortical formation and function. In this study, we demonstrate that microRNA (miR)-128 regulates
Externí odkaz:
https://doaj.org/article/aa2bd3fb12e34d8bb2f1789e3fe31d04
Autor:
Mui Hoon Nai, Hoang-Dai Tran, Huck-Hui Ng, Chwee Teck Lim, Kah-Leong Lim, Haidun Yan, Koji Itahana, Menglan Zhang, Stephanie Wai Lin Lim, Qiang Yuan, Yoko Itahana, Giuseppe D'Agostino, Yong-hui Jiang, Alfred Xuyang Sun, Eng-King Tan, Danlei Wang, Hidayat Lokman, Owen J. L. Rackham, Weonjin Yu, Stuart A. Cook, Grace Lim, Ya Yin Chang, Masahiro Fukuda, Hyunsoo Shawn Je, Jiong Tang
Publikováno v:
Science. 366:1486-1492
Hyperexcitable neurons in brain organoids Individuals with Angelman syndrome experience intellectual disability and seizures throughout their lives. In this condition, ubiquitin-mediated degradation of a key potassium channel is disrupted, allowing f
Autor:
Hidayat Lokman, Huck-Hui Ng, Audrey Tze Ting Khoo, Wei-Yi Ong, Junghyun Jo, Grace Lim, Hoang Dai Tran, Seung-Jae Lee, Weonjin Yu, Lin Yang, Lai Ping Yaw, Ya Yin Chang, Jessica Jiaxin Xie, Kah-Leong Lim, Bin Xiao, Eng-King Tan, Tzuen Yih Saw, Byung Chul Jung, Alfred Xuyang Sun, Hyunsoo Shawn Je
Publikováno v:
Annals of neurology. 90(3)
Objective: We utilized human midbrain-like organoids (hMLOs) generated from human pluripotent stem cells carrying glucocerebrosidase gene (GBA1) and α-synuclein (α-syn; SNCA) perturbations to investigate genotype-to-phenotype relationships in Parki
Autor:
Shawn Tan, Yixin Xiao, Audrey Khoo Tze Ting Ting, Weonjin Yu, H. Shawn Je, Taejoon Kwon, Won-Kyung Ho, Hidayat Lokman, Young-Hwan Lee, Hasini Ganegala, Yi-Chun Yen
Publikováno v:
Molecular Brain
Molecular Brain, Vol 12, Iss 1, Pp 1-13 (2019)
Molecular Brain, Vol 12, Iss 1, Pp 1-13 (2019)
Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed antidepressant drugs in pregnant women. Infants born following prenatal exposure to SSRIs have a higher risk for behavioral abnormalities, however, the underlying mechanisms rema
Autor:
Weonjin Yu, Yen, Yi-Chun, Young-Hwan Lee, Tan, Shawn, Yixin Xiao, Hidayat Lokman, Ting, Audrey, Hasini Ganegala, Taejoon Kwon, Won-Kyung Ho, H. Je
Figure S1. Prenatal FLX treatment does not induce other behavioral deficits. Figure S2. The prenatal FLX treatment does not change the morphology or spine density of L5 PrL neurons. Figure S3. Passive membrane properties of FS interneurons in the PrL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a4990076803d95a722f792cdac1d0a
Autor:
Hidayat Lokman, Steven G. Rozen, Ke Zhang, Lifeng Qiu, Paul Jong Kim, Hyunsoo Shawn Je, Wei Zhang, Eng-King Tan, Li Zeng, Zhongcan Chen
Publikováno v:
eLife, Vol 5 (2016)
eLife
eLife
During the development, tight regulation of the expansion of neural progenitor cells (NPCs) and their differentiation into neurons is crucial for normal cortical formation and function. In this study, we demonstrate that microRNA (miR)-128 regulates
Autor:
Steven G. Rozen, Ke Zhang, Hidayat Lokman, Hyunsoo Shawn Je, Li Zeng, Lifeng Qiu, Zhongcan Chen, Paul Jong Kim, Eng-King Tan, Wei Zhang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eee4b06fcfba04b951a5b77f9c70aed
https://doi.org/10.7554/elife.11324.039
https://doi.org/10.7554/elife.11324.039