Výsledky vyhledávání - "Hidalgo Hernando, Elena"

Formation of transient protein aggregate-like centers is a general strategy postponing degradation of misfolded intermediates

Autor: Boronat i Llop, Susanna, 1965, Cabrera, Margarita, Vega, Montserrat, Alcalá, Jorge, Salas Pino, Silvia, Daga, Rafael R., Ayté del Olmo, José, Hidalgo Hernando, Elena

This work is supported by grants PGC2018-093920-B-I00 and PID2021-122837NB-I00 funded by MICIN/AEI/10.13039/501100011033/FEDER, UE to E.H., funded by Ministerio de Ciencia e Innovación, Agencia Estatal de Investigación and Fondo Europeo de Desarrol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1610::5a04985b496059e53eb2c63f8933d7ea
http://hdl.handle.net/10230/57523

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Genome-wide screening of regulators of catalase expression: role of a transcription complex and histone and tRNA modification complexes on adaptation to stress

Autor: García Rodríguez, Patricia, Encinar del Dedo, Javier, Ayté del Olmo, José, Hidalgo Hernando, Elena

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
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In response to environmental cues, the mitogen-activated protein kinase Sty1-driven signaling cascade activates hundreds of genes to induce a robust anti-stress cellular response in fission yeast. Thus, upon stress imposition Sty1 transiently accumul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::63c88e0bd29e7c499ad271b804326ab0
http://hdl.handle.net/10230/25571

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Methionine sulphoxide reductases revisited: free methionine as a primary target of H2O2 stress in auxotrophic fission yeast

Autor: García Santamarina, Sarela, 1978, Boronat i Llop, Susanna, 1965, Ayté del Olmo, José, Hidalgo Hernando, Elena

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
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Amino acid methionine can suffer reversible oxidation to sulphoxide and further irreversible over-oxidation to methionine sulphone. As part of the cellular antioxidant scavenging activities are the methionine sulphoxide reductases (Msrs), with a repo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::05b082335590800b7b734b84a7dc5dad
http://hdl.handle.net/10230/25576

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The peroxiredoxin Tpx1 is essential as a H202-scavenger during aerobic growth in fission yeast

Autor: Jara, Mónica, Vivancos Prellezo, Ana, Calvo, Isabel A., Moldón Vara, Alberto, Sansó Martínez, Miriam, 1979, Hidalgo Hernando, Elena

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
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Peroxiredoxins are known to interact with hydrogen peroxide (H2O2) and to participate in oxidant scavenging, redox signal transduction, and heat-shock responses. The two-cysteine peroxiredoxin Tpx1 of Schizosaccharomyces pombe has been characterized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8bea2cd6d535fbfe76ee942e246ecda6
http://hdl.handle.net/10230/16369

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A genetic approach to study H2O2 scavenging in fission yeast--distinct roles of peroxiredoxin and catalase

Autor: Paulo Mirasol, Esther, 1984, García Santamarina, Sarela, 1978, Calvo, Isabel A., Carmona, Mercè, Boronat i Llop, Susanna, 1965, Domènech, Alba, Ayté del Olmo, José, Hidalgo Hernando, Elena

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
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The main peroxiredoxin in Schizosaccharomyces pombe, Tpx1, is important to sustain aerobic growth, and cells lacking this protein are only able to grow on solid plates under anaerobic conditions. We have found that deletion of the gene coding for thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9347752967c049757ec26868ab6275dc
http://hdl.handle.net/10230/25568

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A new negative feedback mechanism for MAPK pathway inactivation through Srk1 MAPKAP kinase

Autor: Maribel Marquina, Eva Lambea, Mercé Carmona, Marta Sánchez-Marinas, Sandra López-Aviles, José Ayte, Elena Hidalgo, Rosa Aligue

The fission yeast mitogen-activated kinase (MAPK) Sty1 is essential for cell survival in response to different environmental insults. In unstimulated cells, Sty1 forms an inactive ternary cytoplasmatic complex with the MAPKK Wis1 and the MAPKAP kinas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c658736ddd0b75cf34ad468bb2ac6171
http://hdl.handle.net/10230/55182

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Native RNA sequencing in fission yeast reveals frequent alternative splicing isoforms

Autor: José Carlos Montañés, Marta Huertas, Simone G. Moro, William R. Blevins, Mercè Carmona, José Ayté, Elena Hidalgo, M. Mar Albà

Publikováno v: Genome research.

The unicellular yeast Schizosaccharomyces pombe (fission yeast) retains many of the splicing features observed in humans and is thus an excellent model to study the basic mechanisms of splicing. Nearly half the genes contain introns, but the impact o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2729f2926b57c9241ccb918cd8d33ef
https://pubmed.ncbi.nlm.nih.gov/35618415

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Role of the MAP kinase Sty1 and the transcription factor Atf1 in euchromatin and heterochromatin dynamics in Schizosaccharomyces pombe

Autor: Fraile Beneitez, Rodrigo, 1992

Publikováno v: TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
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Eukaryotic DNA is condensed inside the nucleus, compacted into chromatin. The structure of chromatin is dynamic, and its accessibility to cellular machinery can be altered depending on the level of chromatin compaction (euchromatin or heterochromatin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::0d3c55af9cd7ddd53ff0e1b8f26fca82
http://hdl.handle.net/10803/672619

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Role of the protein quality control system in basal and stress conditions in fission yeast

Autor: Marte, Luis, 1990

Publikováno v: TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname

Proteostasis is the proper homeostasis of the concentration and the molecular structure of the proteins, which preserves the integrity of the proteome. Proteo-stasis is constantly challenged by intrinsic and extrinsic factors which must be buffered b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::20e117bd7becedb7d4ec28e02e6d9449
http://hdl.handle.net/10803/668496

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Nuclear and non-nuclear roles of the MAP kinase Sty1 on cell cycle, cell polarity and transcription

Autor: Salat Canela, Clàudia, 1989

Publikováno v: TDX (Tesis Doctorals en Xarxa)
TDR: Tesis Doctorales en Red
CBUC, CESCA
TDR. Tesis Doctorales en Red
instname

Living organisms must respond to changes in their environment in order to overcome stress situations. In Schizosaccharomyces pombe, Sty1 MAP kinase is required to survive to a wide range of environmental stresses. The main outcome of Sty1 activation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::afe1d2510a66857768fecc33ed6bac94
http://hdl.handle.net/10803/670276

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