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of 2 318
pro vyhledávání: '"Hickling P"'
Autor:
Hickling, Tennessee, Prangle, Dennis
Normalizing flows are a flexible class of probability distributions, expressed as transformations of a simple base distribution. A limitation of standard normalizing flows is representing distributions with heavy tails, which arise in applications to
Externí odkaz:
http://arxiv.org/abs/2406.16971
Autor:
Hickling, Tennessee, Prangle, Dennis
We propose a transformation capable of altering the tail properties of a distribution, motivated by extreme value theory, which can be used as a layer in a normalizing flow to approximate multivariate heavy tailed distributions. We apply this approac
Externí odkaz:
http://arxiv.org/abs/2311.00580
The use of Deep Reinforcement Learning (DRL) schemes has increased dramatically since their first introduction in 2015. Though uses in many different applications are being found, they still have a problem with the lack of interpretability. This has
Externí odkaz:
http://arxiv.org/abs/2207.01911
Autor:
Michel Siegel, Anna-Lena Bolender, Axel Ducret, Johannes Fraidling, Katharina Hartman, Cary M. Looney, Olivier Rohr, Timothy P. Hickling, Hubert Kettenberger, Martin Lechmann, Céline Marban-Doran, Thomas E. Kraft
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionImmunogenicity, the unwanted immune response triggered by therapeutic antibodies, poses significant challenges in biotherapeutic development. This response can lead to the production of anti-drug antibodies, potentially compromising the e
Externí odkaz:
https://doaj.org/article/c01676e863fb443ca2e5f23f30eb48a1
Autor:
Michel Siegel, Aman Padamsey, Anna-Lena Bolender, Patrick Hargreaves, Johannes Fraidling, Axel Ducret, Katharina Hartman, Cary M. Looney, Cristina Bertinetti-Lapatki, Olivier Rohr, Timothy P. Hickling, Thomas E. Kraft, Céline Marban-Doran
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionImmunogenicity refers to the ability of a substance, such as a therapeutic drug, to elicit an immune response. While beneficial in vaccine development, undesirable immunogenicity can compromise the safety and efficacy of therapeutic prote
Externí odkaz:
https://doaj.org/article/7d40f92e19414c188759d42872e0dd4b
Autor:
Tríona McCaffrey, Catherine E. Carr, Hans Petter Paulen Solli, Cornelia Bent, Darmuid Boyle, Oda Bjørke Dypvik, Kenneth Dybdahl, Tommy Hayes, Lauren M. Hickling, Jane Fernandez, Anne Malerbakken, Brendan Ruddy, Torgrim Vågan
Publikováno v:
Voices, Vol 24, Iss 2 (2024)
The mental health recovery movement recognises the importance of expertise by experience held by service users alongside healthcare practitioners. Recovery has gained attention in music therapy but a situation prevails where practitioners and researc
Externí odkaz:
https://doaj.org/article/4c435b7fb20746a49a3dfb0f90fbfc35
The dangers of adversarial attacks on Uncrewed Aerial Vehicle (UAV) agents operating in public are increasing. Adopting AI-based techniques and, more specifically, Deep Learning (DL) approaches to control and guide these UAVs can be beneficial in ter
Externí odkaz:
http://arxiv.org/abs/2206.02670
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Misclassification bias (MB) is the deviation of measured from true values due to incorrect case assignment. This study compared MB when cystectomy status was determined using administrative database codes vs. predicted cystectomy
Externí odkaz:
https://doaj.org/article/f516b773283b41549a4a09b3ea58bf30
Autor:
Gina SA Trapp, Natasha Reid, Siobhan Hickling, Alexia Bivoltsis, Joelie Mandzufas, Justine Howard
Publikováno v:
Public Health Nutrition, Vol 26, Pp 1451-1455 (2023)
Abstract Objective: It is unknown whether the nutritional quality of children’s menus varies depending on the cuisine type. This study aimed to investigate differences in the nutritional quality of children’s menus by cuisine type in restaurants
Externí odkaz:
https://doaj.org/article/cf8e0e70651d476f806c175dcbdb62c9
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